Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Leslie Wilkinson"'
Autor:
Casey Pence, Majed Matar, David Ulkoski, Leslie Wilkinson, Jason G. Fewell, Elaine Brunhoeber, Kirby Wallace, Diane McClure, Gregory Slobodkin, Jennifer Rice, Richard Congo, Angela Rea-Ramsey, Kevin Polach, Jeff Sparks, Khursheed Anwer
Publikováno v:
Journal of Controlled Release. 158:269-276
Exploitation of the RNA interference (RNAi) pathway offers the promise of new and effective therapies for a wide variety of diseases. Clinical development of new drugs based on this platform technology is still limited, however, by a lack of safe and
Autor:
Kevin Polach, Casey Pence, Khursheed Anwer, Angela Rea-Ramsey, Jennifer Rice, Jason G. Fewell, Elaine Brunhoeber, Diane McClure, Majed Matar, Leslie Wilkinson, Jeff Sparks
Publikováno v:
Cancer Research. 72:B17-B17
Exploiting the RNAi pathway offers the potential to advance the treatment of many diseases through highly specific and efficient silencing of gene products. Unfortunately, the requisite safe and efficient delivery of nucleic acids to target cells rem
Autor:
Elaine Brunhoeber, Richard Congo, Gregory Slobodkin, Jennifer Rice, Angela Rea-Ramsey, Khursheed Anwer, Jason G. Fewell, Jeff Sparks, Kevin Polach, Casey Pence, Majed Matar, Diane McClure, Leslie Wilkinson
Publikováno v:
Cancer Research. 71:4995-4995
RNA interference offers the promise of a new class of therapeutics that can specifically target many diseases that have aberrant gene expression as the root cause. This is potentially true even for diseases that are currently considered non-druggable
Autor:
Jason G. Fewell, Diane McClure, Jeff Sparks, Majed Matar, Angela Rea-Ramsey, Elaine Brunhoeber, Jennifer Rice, Gregory Slobodkin, Richard Congo, Khursheed Anwer, Casey Pence, Kevin Polach, Leslie Wilkinson
Publikováno v:
Cancer Research. 70:5535-5535
The efficient delivery of siRNA molecules to target cells is critical for the application of RNAi to the treatment of human cancers. To this end, we have developed novel cationic lipopolyamime structures that can be used to complex or encapsulate siR
Autor:
Alfred Fischer, Alan Leslie Wilkinson
Publikováno v:
Canadian Journal of Chemistry. 50:3988-3992
cis and trans isomers of 1,4-dimethyl-4-nitro-1,4-dihydro-1-naphthyl acetate (1) have been isolated from a mixture of 1,4-dimethylnaphthalene and nitric acid in acetic anhydride by quenching at −40°. At room temperature only 1-methyl-4-nitromethyl
Autor:
Alfred Fischer, Alan Leslie Wilkinson
Publikováno v:
Chemischer Informationsdienst. 4