Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Leslie W.J. Baillie"'
Autor:
Ahmed G. Eissa, James A. Blaxland, Rhodri O. Williams, Kamel A. Metwally, Sobhy M. El-Adl, El-Sayed M. Lashine, Leslie W.J. Baillie, Claire Simons
Publikováno v:
Bulletin of Faculty of Pharmacy Cairo University, Vol 54, Iss 2, Pp 197-207 (2016)
As part of our ongoing research efforts to develop new antibacterial agents acting on novel molecular targets, a series of twenty-two adenine and benzimidazole-based mimics of the lead compound REP-3123 was designed to target methionyl-tRNA synthetas
Externí odkaz:
https://doaj.org/article/9cd58432d92247aa94f77adeedd8e564
Autor:
E. D. Williamson, Yusuf Ozkul, Rosemary J. Boyton, Rebecca J. Ingram, Bernard Maillere, Daniel M. Altmann, Leslie W.J. Baillie, John H. Robinson, Theresa Gallagher, Hugh Dyson, Steven A. Moore, Mehmet Doganay, Gökhan Metan, Karen K. Y. Chu, Stephanie Ascough
The causative agent of anthrax, Bacillus anthracis, evades the host immune response and establishes infection through the production of binary exotoxins composed of Protective Antigen (PA) and one of two subunits, lethal factor (LF) or edema factor (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98d2c362414e492ab56b4d1ffa35b5b
Autor:
Helen S. Atkins, Stephen James Moore, James P. Nataro, Chiguang Feng, Ana L. Rodriguez, Leslie W.J. Baillie, Marcela F. Pasetti
Publikováno v:
Vaccine. 26:6083-6091
We previously demonstrated the ability of an orally administered attenuated Salmonella enterica serovar Typhimurium strain expressing the protective antigen (PA) of Bacillus anthracis to confer protection against lethal anthrax aerosol spore challeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b92f1445f1b814803dd9553eb4035d
https://doi.org/10.1016/j.vaccine.2008.09.010
https://doi.org/10.1016/j.vaccine.2008.09.010
Autor:
Tom Pottage, Callum Cooper, Fatih Büyük, Mitat Şahin, Suzanna Hawkey, Leslie W.J. Baillie, Ant Crook, Allan Bennett, Özgür Çelebi
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 7 (2016)
Frontiers in Microbiology, Vol 7 (2016)
Elimination of Bacillus anthracis spores from the environment is a difficult and costly process due in part to the toxicity of current sporicidal agents. For this reason we investigated the ability of the spore germinants L-alanine (100 mM) and inosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1da510d40e706af61c9917253f5183
Autor:
Rhodri O. Williams, Ahmed G. Eissa, James A. Blaxland, Kamel Metwally, El-Sayed M. Lashine, Leslie W.J. Baillie, Claire Simons, Sobhy M. El-Adl
The synthesis of a series of benzimidazole-N-benzylpropan-1-amines and adenine-N-benzylpropan-1-amines is described. Subsequent evaluation against two strains of the anaerobic bacterium Clostridium difficile was performed with three amine derivatives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b12303169bb6a89da1284c3068028a5
https://orca.cardiff.ac.uk/id/eprint/87911/2/Targeting%20methionyl%20tRNA%20synthetase-%20design%2C%20synthesis%20and%20antibacterial%20activity%20against%20Clostridium%20difficile%20of%20novel%203-biaryl-N-benzylpropan-1-amine%20derivatives.pdf
https://orca.cardiff.ac.uk/id/eprint/87911/2/Targeting%20methionyl%20tRNA%20synthetase-%20design%2C%20synthesis%20and%20antibacterial%20activity%20against%20Clostridium%20difficile%20of%20novel%203-biaryl-N-benzylpropan-1-amine%20derivatives.pdf
Autor:
Leslie W.J. Baillie
Publikováno v:
Human vaccines. 5(12)
Anthrax is caused by a Gram-positive aerobic spore-forming bacillus called Bacillus anthracis. Although primarily a disease of animals, it can also infect man, sometimes with fatal consequences. As a result of concerns over the illicit use of this or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e1a6acf3b36694a41872e754f96d305
https://pubmed.ncbi.nlm.nih.gov/19786839
https://pubmed.ncbi.nlm.nih.gov/19786839
Autor:
Rebecca J. Hornby, Leslie W.J. Baillie, Nicola C. Bailey, Lucy J. Wilkinson, E. Hugh Dyson, Andrew J. H. Simpson, Matthew G. Bell, Matthew J. Hepburn, Alfred J. Mateczun, Karen E. Brenneman
Publikováno v:
Vaccine. 25(32)
A pilot study compared the immune response of regular (0, 3, 6, 32 weeks) and extended (0, 10, 13, 32 weeks) schedules of the UK anthrax vaccine (anthrax vaccine precipitated, AVP). Concentrations of antibodies to protective antigen (PA) were higher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e7b5baf96a217987cb838236d0fcf47
https://pubmed.ncbi.nlm.nih.gov/17604880
https://pubmed.ncbi.nlm.nih.gov/17604880
Autor:
El-Sayed M. Lashine, Sobhy M. El-Adl, Claire Simons, Kamel Metwally, James A. Blaxland, Rhodri O. Williams, Ahmed G. Eissa, Leslie W.J. Baillie
Publikováno v:
Bulletin of Faculty of Pharmacy, Cairo University, Vol 54, Iss 2, Pp 197-207 (2016)
As part of our ongoing research efforts to develop new antibacterial agents acting on novel molecular targets, a series of twenty-two adenine and benzimidazole-based mimics of the lead compound REP-3123 was designed to target methionyl-tRNA synthetas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75897aa726cfe3e0d02067733b6d590d
Autor:
Baillie, L. W. J.
Publikováno v:
Letters in Applied Microbiology; Sep2005, Vol. 41 Issue 3, p227-229, 3p