Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Leslie W Tari"'
Autor:
María Hernández, Simon Dohrmann, James Levin, Nicholas Dedeic, Amanda Almaguer, Doug Zuill, Elizabeth Abelovski, Rajvir Grewal, Joanne Fortier, Qiping Zhao, Karin Amundson, Madison Moniz, Hongyuan Chen, Dhanya Panicker, Thanh Lam, Thomas P Brady, Allen Borchardt, Jason N Cole, Leslie W Tari
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/b93c42d0c77e42c1ac770d82acb13595
Autor:
Leslie W Tari, Xiaoming Li, Michael Trzoss, Daniel C Bensen, Zhiyong Chen, Thanh Lam, Junhu Zhang, Suk Joong Lee, Grayson Hough, Doug Phillipson, Suzanne Akers-Rodriguez, Mark L Cunningham, Bryan P Kwan, Kirk J Nelson, Amanda Castellano, Jeff B Locke, Vickie Brown-Driver, Timothy M Murphy, Voon S Ong, Chris M Pillar, Dean L Shinabarger, Jay Nix, Felice C Lightstone, Sergio E Wong, Toan B Nguyen, Karen J Shaw, John Finn
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e84409 (2013)
Increasing resistance to every major class of antibiotics and a dearth of novel classes of antibacterial agents in development pipelines has created a dwindling reservoir of treatment options for serious bacterial infections. The bacterial type IIA t
Externí odkaz:
https://doaj.org/article/61b9ed4eb647499192d901bd0163432e
Autor:
Isaac Hoffman, Terry R. Stouch, Ronald V. Swanson, Qingyun Liu, Michael J. Hunter, Leslie W. Tari, Giovanni Cianchetta, Wangsheng Yu, Zhi-Cai Shi
Publikováno v:
Current Chemical Genomics
Trytophan Hydroxylase Type I (TPH1), most abundantly expressed in the gastrointestinal tract, initiates the synthesis of serotonin by catalyzing hydroxylation of tryptophan in the presence of biopterin and oxygen. We have previously described three s
Publikováno v:
Journal of Biological Chemistry. 280:5820-5827
The uptake of the element iron is vital for the survival of most organisms. Numerous pathogenic Gram-negative bacteria utilize a periplasm-to-cytosol ATP-binding cassette transport pathway to transport this essential atom in to the cell. In this stud
Autor:
Percy Rhodes, Enrique E. Abola, Daniel C. Carter, Raymond C. Stevens, Gyorgy Snell, Duncan E. McRee, D.R. Dougan, Leslie W. Tari
Publikováno v:
Journal of Applied Crystallography. 38:87-90
Preliminary studies suggest that protein crystallization experiments using nanoliter-volume protein crystallization droplets may produce equal or better quality protein crystals compared with those grown using microliter volumes, and sometimes produc
Autor:
Stephen R. Shouldice, Pamela A. Williams, Daniel Scheibe, Gyorgy Snell, David J. Hosfield, Leslie W. Tari, D.R. Dougan, Duncan E. McRee, Anthony B. Schryvers, Shane D. Kirby, Robert J. Skene
Publikováno v:
Journal of Biological Chemistry. 278:41093-41098
Pasteurellosis caused by the Gram-negative pathogen Pasteurella haemolytica is a serious disease leading to death in cattle. To scavenge growth-limiting iron from the host, the pathogen utilizes the periplasmic ferric ion-binding protein A (PhFbpA) a
Autor:
Leslie W. Tari, Robert J Skene, Stephen R. Shouldice, Duncan E McRee, D.R. Dougan, Anthony B. Schryvers
Publikováno v:
Biochemistry. 42:11908-11914
The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria from the Pasteurellaceae and Neisseriaceae families and is critical for survival of these pathogens within the host. In this
Publikováno v:
Biochemistry and Cell Biology. 81:275-283
Pathogenic Gram-negative bacteria of the Pasteurellaceae and Neisseriaceae acquire iron for growth from host transferrin through the action of specific surface receptors. Iron is removed from transferrin by the receptor at the cell surface and is tra
Autor:
Stephen R. Shouldice, Rong-hua Yu, Anthony B. Schryvers, D.R. Dougan, Robert J. Skene, Leslie W. Tari, Duncan E. McRee
Publikováno v:
Journal of Biological Chemistry. 278:11513-11519
The periplasmic iron binding protein of pathogenic Gram-negative bacteria performs an essential role in iron acquisition from transferrin and other iron sources. Structural analysis of this protein from Haemophilus influenzae identified four amino ac
Publikováno v:
Journal of Biological Chemistry. 277:13966-13972
Siderophore-binding proteins play an essential role in the uptake of iron in many Gram-positive and Gram-negative bacteria. FhuD is an ATP-binding cassette-type (ABC-type) binding protein involved in the uptake of hydroxamate-type siderophores in Esc