Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Leslie Tung"'
Autor:
Geran M. Kostecki, Yu Shi, Christopher S. Chen, Daniel H. Reich, Emilia Entcheva, Leslie Tung
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Interactions between cardiac myofibroblasts and myocytes may slow conduction and generate spontaneous beating in fibrosis, increasing the chance of life-threatening arrhythmia. While co-culture studies have shown that myofibroblasts can affe
Externí odkaz:
https://doaj.org/article/e51090c71a604ba8a2fb67956066842a
Autor:
ThuyVy Duong, Rebecca Rose, Adriana Blazeski, Noah Fine, Courtney E. Woods, Joseph F. Thole, Nona Sotoodehnia, Elsayed Z. Soliman, Leslie Tung, Andrew S. McCallion, Dan E. Arking
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
Clinically pertinent electrocardiogram (ECG) data from model systems, such as zebrafish, are crucial for illuminating factors contributing to human cardiac electrophysiological abnormalities and disease. Current zebrafish ECG collection strategies ha
Externí odkaz:
https://doaj.org/article/91bf522f3be94c878d1d046719b0bb10
Autor:
Adriana Blazeski, Justin Lowenthal, Renjun Zhu, Jourdan Ewoldt, Kenneth R. Boheler, Leslie Tung
Publikováno v:
Stem Cell Reports, Vol 12, Iss 5, Pp 982-995 (2019)
Summary: Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) hold great promise for cardiac studies, but their structural and functional immaturity precludes their use as faithful models of adult myocardium. Here we describe engine
Externí odkaz:
https://doaj.org/article/e6cfb87ed9764217b525263e651c56fc
Autor:
Chin Siang Ong, Takuma Fukunishi, Huaitao Zhang, Chen Yu Huang, Andrew Nashed, Adriana Blazeski, Deborah DiSilvestre, Luca Vricella, John Conte, Leslie Tung, Gordon F. Tomaselli, Narutoshi Hibino
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract We have developed a novel method to deliver stem cells using 3D bioprinted cardiac patches, free of biomaterials. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs), fibroblasts (FB) and endothelial cells (EC) were aggreg
Externí odkaz:
https://doaj.org/article/6e7b7ecb133a4b4abea17c9f5d020bd8
Autor:
Seth H Weinberg, Leslie Tung
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40477 (2012)
Alternans is a beat-to-beat alternation of the cardiac action potential duration (APD) or intracellular calcium (Ca(i)) transient. In cardiac tissue, alternans can be spatially concordant or discordant, of which the latter has been shown to increase
Externí odkaz:
https://doaj.org/article/ee1b395299a64e8ebac3d10e379901e4
Autor:
Paul W Burridge, Susan Thompson, Michal A Millrod, Seth Weinberg, Xuan Yuan, Ann Peters, Vasiliki Mahairaki, Vassilis E Koliatsos, Leslie Tung, Elias T Zambidis
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18293 (2011)
The production of cardiomyocytes from human induced pluripotent stem cells (hiPSC) holds great promise for patient-specific cardiotoxicity drug testing, disease modeling, and cardiac regeneration. However, existing protocols for the differentiation o
Externí odkaz:
https://doaj.org/article/c68c721930e24e289ccb28097a812e54
Autor:
Olga Amaral, Enrico Bertini, José Bragança, Esra Cagavi, Claudia Compagnucci, Ana Duarte, Julian A. Gingold, Subhajit Giri, Mo-Fan Huang, Shilpa Iyer, Yoon-Young Jang, Dung-Fang Lee, Justin Lowenthal, Brigitte Malgrange, Fibi Meshrkey, Ryuji Morizane, Ozlem Mutlu Burnaz, Lon Kai Pang, Mezthly Pena, Raj R. Rao, Diogo Ribeiro, Renato Santos, Marco Tartaglia, Gordon F. Tomaselli, Tamara Traitteur, Leslie Tung, Heidi Ulrichs, Yichen Wang, Franklin D. West, Hsueh Fu Wu, Brenda Yang, Nadja Zeltner, Chengcheng Zhang, Ruiying Zhao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10e1f9cf3f4253c68cf9068ccd2b34f9
https://doi.org/10.1016/b978-0-323-85767-3.01002-1
https://doi.org/10.1016/b978-0-323-85767-3.01002-1
Autor:
Michael A. Laflamme, Joseph C. Wu, Charles E. Murry, Kevin Gray, Eunpyo Choi, Alec S.T. Smith, Elisa C. Clark, Deok Ho Kim, Leslie Tung, Jesse Macadangdang, Eun Hyun Ahn
Publikováno v:
Nano Lett
Matrix nanotopographical cues are known to regulate the structure and function of somatic cells derived from human pluripotent stem cell (hPSC) sources. High-throughput electrophysiological analysis of excitable cells derived from hPSCs is possible v
Autor:
Joseph F. Thole, Elsayed Z. Soliman, Dan E. Arking, Andrew S. McCallion, Nona Sotoodehnia, Rebecca Rose, Courtney E. Woods, Adriana Blazeski, Noah Fine, Leslie Tung, Thuy Vy Duong
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
article-version (VoR) Version of Record
Disease Models & Mechanisms, Vol 14, Iss 8 (2021)
Clinically pertinent electrocardiogram (ECG) data from model systems, such as zebrafish, are crucial for illuminating factors contributing to human cardiac electrophysiological abnormalities and disease. Current zebrafish ECG collection strategies ha