Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Leslie S. Itsara"'
Autor:
Yaxian Zhou, Kiara Hatzakis, Zachary MacMillen, Mint Laohajaratsang, Alexis M. Grieser, Leslie S. Itsara, Julie Do, James W. Davie, Anil K. Ghosh, Marion Avril
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Plasmodium falciparum oocysts undergo growth and maturation in a unique setting within the mosquito midgut, firmly situated between the epithelium and the basal lamina. This location exposes them to specific nutrient exchange and
Externí odkaz:
https://doaj.org/article/a1cc2cbd773946feb0b5f7c1091c60d3
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-10 (2020)
Abstract Background Plasmodium falciparum zygotes develop in the mosquito midgut after an infectious blood meal containing mature male and female gametocytes. Studies of mosquito-produced P. falciparum zygotes to elucidate their biology and developme
Externí odkaz:
https://doaj.org/article/95ce0b93c2734790b5204c1a35b909bf
Autor:
Leslie S. Itsara, Yaxian Zhou, Julie Do, Samrita Dungel, Matthew E. Fishbaugher, Will W. Betz, Thao Nguyen, Mary Jane Navarro, Erika L. Flannery, Ashley M. Vaughan, Stefan H. I. Kappe, Anil K. Ghosh
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-13 (2018)
Abstract Background Despite the importance of the Plasmodium berghei oocyst capsule protein (PbCap380) in parasite survival, very little is known about the orthologous Plasmodium falciparum capsule protein (PfCap380). The goal of this work was to stu
Externí odkaz:
https://doaj.org/article/6f4b2269acd6441080313f82bdc857a3
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Each year malaria kills hundreds of thousands of people and infects hundreds of millions of people despite current control measures. An effective malaria vaccine will likely be necessary to aid in malaria eradication. Vaccination using whole sporozoi
Externí odkaz:
https://doaj.org/article/5da4bddcf45b41c5b02ade45c7b6b629
Autor:
Jonathon L. Burman, Leslie S. Itsara, Ernst-Bernhard Kayser, Wichit Suthammarak, Adrienne M. Wang, Matt Kaeberlein, Margaret M. Sedensky, Philip G. Morgan, Leo J. Pallanck
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 10, Pp 1165-1174 (2014)
Mutations affecting mitochondrial complex I, a multi-subunit assembly that couples electron transfer to proton pumping, are the most frequent cause of heritable mitochondrial diseases. However, the mechanisms by which complex I dysfunction results in
Externí odkaz:
https://doaj.org/article/c740b63f6a234240b974a741f333415a
Autor:
Samrita Dungel, Yaxian Zhou, Leslie S. Itsara, Ashley M. Vaughan, Anil K. Ghosh, Stefan H. I. Kappe, Matthew Fishbaugher, Julie Do, Will Betz, Thao Nguyen, Mary Jane Navarro, Erika L. Flannery
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-13 (2018)
Malaria Journal
Malaria Journal
Background Despite the importance of the Plasmodium berghei oocyst capsule protein (PbCap380) in parasite survival, very little is known about the orthologous Plasmodium falciparum capsule protein (PfCap380). The goal of this work was to study the gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b9d48d00592ca7de512f36e273894b9
http://link.springer.com/article/10.1186/s12936-018-2277-6
http://link.springer.com/article/10.1186/s12936-018-2277-6
Autor:
Philip G. Morgan, Renjini Ramadasan-Nair, Jessica Hui, Leslie S. Itsara, Margaret M. Sedensky
WHAT WE ALREADY KNOW ABOUT THIS TOPIC In mice, restriction of loss of the mitochondrial complex I gene Ndufs4 to glutamatergic neurons confers a profound hypersensitivity to volatile anesthetics.Astrocytes are crucial to glutamatergic synapse functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e853476f93f164eb09a28fd55b8312ce
https://europepmc.org/articles/PMC6375739/
https://europepmc.org/articles/PMC6375739/
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Each year malaria kills hundreds of thousands of people and infects hundreds of millions of people despite current control measures. An effective malaria vaccine will likely be necessary to aid in malaria eradication. Vaccination using whole sporozoi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f0639022f33bfb1a8dec8f9bf2c773
https://doi.org/10.3389/fimmu.2018.02748
https://doi.org/10.3389/fimmu.2018.02748
Autor:
Jessica Hui, Leslie S. Itsara, Renjini Ramadasan-Nair, Philip G. Morgan, Margaret M. Sedensky, Pavel I. Zimin
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188087 (2017)
PLoS ONE
PLoS ONE
Knockout of the mitochondrial complex I protein, NDUFS4, profoundly increases sensitivity of mice to volatile anesthetics. In mice carrying an Ndufs4lox/lox gene, adeno-associated virus expressing Cre recombinase was injected into regions of the brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5ed57fc894dfc8ee819b794997f6de
http://europepmc.org/articles/PMC5685608?pdf=render
http://europepmc.org/articles/PMC5685608?pdf=render
Autor:
Margaret M. Sedensky, Wichit Suthammarak, Jonathon L. Burman, Leslie S. Itsara, Ernst Bernhard Kayser, Matt Kaeberlein, Adrienne M. Wang, Philip G. Morgan, Leo J. Pallanck
Publikováno v:
Disease Models & Mechanisms, Vol 7, Iss 10, Pp 1165-1174 (2014)
Disease Models & Mechanisms
Disease Models & Mechanisms
Mutations affecting mitochondrial complex I, a multi-subunit assembly that couples electron transfer to proton pumping, are the most frequent cause of heritable mitochondrial diseases. However, the mechanisms by which complex I dysfunction results in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16fdfa331e68d9522f88e2382ea9e3ef
http://dmm.biologists.org/content/7/10/1165
http://dmm.biologists.org/content/7/10/1165