Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Leslie S Gewin"'
Autor:
Alan J Simmons, Amrita Banerjee, Eliot T McKinley, Cherie’ R Scurrah, Charles A Herring, Leslie S Gewin, Ryota Masuzaki, Seth J Karp, Jeffrey L Franklin, Michael J Gerdes, Jonathan M Irish, Robert J Coffey, Ken S Lau
Publikováno v:
Molecular Systems Biology, Vol 12, Iss 8, Pp n/a-n/a (2016)
Externí odkaz:
https://doaj.org/article/1ce5770923c34fb3ace822f86f5a1119
Autor:
Alan J Simmons, Amrita Banerjee, Eliot T McKinley, Cherie' R Scurrah, Charles A Herring, Leslie S Gewin, Ryota Masuzaki, Seth J Karp, Jeffrey L Franklin, Michael J Gerdes, Jonathan M Irish, Robert J Coffey, Ken S Lau
Publikováno v:
Molecular Systems Biology, Vol 11, Iss 10, Pp n/a-n/a (2015)
Abstract Understanding heterogeneous cellular behaviors in a complex tissue requires the evaluation of signaling networks at single‐cell resolution. However, probing signaling in epithelial tissues using cytometry‐based single‐cell analysis has
Externí odkaz:
https://doaj.org/article/5185166716ec481ca68a9341c25bd14d
Autor:
Yosuke Osaki, Marika Manolopoulou, Alla V. Ivanova, Nicholas Vartanian, Melanie Phillips Mignemi, Justin Kern, Jianchun Chen, Haichun Yang, Agnes B. Fogo, Mingzhi Zhang, Cassianne Robinson-Cohen, Leslie S. Gewin
Publikováno v:
JCI Insight, Vol 7, Iss 12 (2022)
Acute and chronic kidney injuries induce increased cell cycle progression in renal tubules. While increased cell cycle progression promotes repair after acute injury, the role of ongoing tubular cell cycle progression in chronic kidney disease is unk
Externí odkaz:
https://doaj.org/article/081472a840204c38898bd02877027d3b
Autor:
Leslie S. Gewin
Publikováno v:
Nutrients, Vol 13, Iss 5, p 1580 (2021)
The kidney is a highly metabolically active organ that relies on specialized epithelial cells comprising the renal tubules to reabsorb most of the filtered water and solutes. Most of this reabsorption is mediated by the proximal tubules, and high amo
Externí odkaz:
https://doaj.org/article/b39d2fef8a424294a61acf6ad1ef2bea
Autor:
Leslie S. Gewin
Publikováno v:
Genes, Vol 9, Iss 2, p 58 (2018)
Wnt/β-catenin signaling is extremely important for proper kidney development. This pathway is also upregulated in injured renal tubular epithelia, both in acute kidney injury and chronic kidney disease. The renal tubular epithelium is an important t
Externí odkaz:
https://doaj.org/article/39eab7fe4cff4902b648c4fa0ca22b6d
Autor:
Leslie S, Gewin, Megan E, Summers, Julie W, Harral, Christa F, Gaskill, Stellor Nlandu, Khodo, Surekha, Neelisetty, Timothy M, Sullivan, Katharina, Hopp, J Jeffrey, Reese, Dwight J, Klemm, Valentina, Kon, Kevin C, Ess, Wei, Shi, Susan M, Majka
Publikováno v:
Am J Physiol Renal Physiol
Tuberous sclerosis complex 2 (TSC2), or tuberin, is a pivotal regulator of the mechanistic target of rapamycin signaling pathway that controls cell survival, proliferation, growth, and migration. Loss of Tsc2 function manifests in organ-specific cons