Výsledky vyhledávání - "Leslie R. Bisset"

Akademický článek

Artificial 64-Residue HIV-1 Enhancer-Binding Peptide Is a Potent Inhibitor of Viral Replication in HIV-1-Infected Cells

Autor: Mouhssin Oufir, Leslie R. Bisset, Stefan R. K. Hoffmann, Gongda Xue, Stephan Klauser, Bianca Bergamaschi, Alain Gervaix, Jürg Böni, Jörg Schüpbach, Bernd Gutte

Publikováno v: Advances in Virology, Vol 2011 (2011)

An artificial HIV-1 enhancer-binding peptide was extended by nine consecutive arginine residues at the C-terminus and by the nuclear localization signal of SV40 large T antigen at the N-terminus. The resulting synthetic 64-residue peptide was found t

Externí odkaz: https://doaj.org/article/92fc98ba0c004ad3bd069b5d19189400

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Akademický článek

Simple estimation of incident HIV infection rates in notification cohorts based on window periods of algorithms for evaluation of line-immunoassay result patterns.

Autor: Jörg Schüpbach, Martin D Gebhardt, Alexandra U Scherrer, Leslie R Bisset, Christoph Niederhauser, Stephan Regenass, Sabine Yerly, Vincent Aubert, Franziska Suter, Stefan Pfister, Gladys Martinetti, Corinne Andreutti, Thomas Klimkait, Marcel Brandenberger, Huldrych F Günthard, Swiss HIV Cohort Study

Publikováno v: PLoS ONE, Vol 8, Iss 8, p e71662 (2013)

Tests for recent infections (TRIs) are important for HIV surveillance. We have shown that a patient's antibody pattern in a confirmatory line immunoassay (Inno-Lia) also yields information on time since infection. We have published algorithms which,

Externí odkaz: https://doaj.org/article/7c01cb9ceda04fedac9c41aaf214ae94

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A Randomized Trial of Simplified Maintenance Therapy with Abacavir, Lamivudine, and Zidovudine in Human Immunodeficiency Virus Infection

Autor: Enos Bernasconi, Hansjakob Furrer, Milos Opravil, Sabine Yerly, Rainer Weber, Marek Fischer, Huldrych F. Günthard, Bernard Hirschel, Leslie R. Bisset, Colin Howe, Manuel Battegay, Jean Philippe Chave, Pietro Vernazza, Bruno Ledergerber, Adriano Lazzarin, Luc Perrin

Publikováno v: Opravil, Milos; Hirschel, Bernard; Lazzarin, Adriano; Furrer, Hansjakob; Chave, Jean-Philippe; Yerly, Sabine; Bisset, Leslie R.; Fischer, Marek; Vernazza, Pietro; Bernasconi, Enos; Battegay, Manuel; Ledergerber, Bruno; Günthard, Huldrych; Howe, Colin; Weber, Rainer; Perrin, Luc (2002). A Randomized Trial of Simplified Maintenance Therapy with Abacavir, Lamivudine, and Zidovudine in Human Immunodeficiency Virus Infection. Journal of infectious diseases, 185(9), pp. 1251-1260. The University of Chicago Press 10.1086/340312
The Journal of Infectious Diseases, Vol. 185, No 9 (2002) pp. 1251-1260

This randomized study evaluated the efficacy and tolerability of continued treatment with protease inhibitor plus nucleoside-analogue combination regimens (n = 79) or a change to the simplified regimen of abacavir-lamivudine-zidovudine (n = 84) in pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ae535520469334e4699c267e1912b4
http://doc.rero.ch/record/303577/files/185-9-1251.pdf

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Reference values for peripheral blood lymphocyte phenotypes applicable to the healthy adult population in Switzerland

Autor: Leslie R. Bisset, Matthias Kaelin, Elisabeth Ludwig, Thomas L. Lung, Rolf W. Dubs

Publikováno v: European Journal of Haematology. 72:203-212

OBJECTIVES: Use of domestic reference values is known to improve the accuracy of flow cytometric analysis by integrating local variation due to race, gender, and age. In the absence of previously published estimates, we now report establishment of re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::33bd35cd7acba2d20f26a64d5c3fa69e
https://doi.org/10.1046/j.0902-4441.2003.00199.x

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Prevalence of human T-cell leukemia virus types I and II in Switzerland

Autor: Philippe Bürgisser, Leslie R. Bisset, Johann J. Burckhardt, Peter Erb, Jürg Böni, Meri Gorgievski, Jean-Claude Piffaretti, Jörg Schüpbach, Luc Perrin, Walter Fierz, Helen I. Joller-Jemelka

Publikováno v: Journal of Medical Virology. 72:328-337

The retroviruses human immunodeficiency virus (HIV)-1/2 and human T-cell leukemia virus (HTLV)-I/II share modes of transmission, suggesting that efforts to monitor the current HIV-1 epidemic in Switzerland should be complemented by assessment of HTLV

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19c0367a2aad2825f2e5d76fa6653884
https://doi.org/10.1002/jmv.10541

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Ultra-sensitive and specific detection of porcine endogenous retrovirus (PERV) using a sequence-capture real-time PCR approach

Autor: Jorg Dieter Seebach, Cyril Shah, Jörg Schüpbach, Leslie R. Bisset, Jürg Böni

Publikováno v: Journal of Virological Methods. 109:209-216

Use of porcine xenografts presents as a possible solution to the current shortage of human allografts limiting transplantation procedures. While no definitive observation of in vivo porcine endogenous retrovirus (PERV) transmission in humans has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6e72d15c13532129341ed4faa37839
https://doi.org/10.1016/s0166-0934(03)00073-9

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Long-Term Evaluation of T-Cell Subset Changes After Effective Combination Antiretroviral Therapy During Asymptomatic HIV-Infection

Autor: Marek Fischer, Manuel Battegay, Richard W. Cone, Pietro Vernazza, Rolf W. Dubs, Peter Grob, Rainer Weber, Milos Opravil, Leslie R. Bisset

Publikováno v: Journal of Acquired Immune Deficiency Syndromes. 27:266-271

Demonstration of long-lived HIV-reservoirs resistant to the effects of combination antiretroviral therapy raises concern over the ability of treatment to maintain long-term beneficial alterations in T-cell subset composition. To address this issue, w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5106caf10aeae227d813ec79c9206ca8
https://doi.org/10.1097/00042560-200107010-00008

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Effects of Early Antiretroviral Treatment on HIV-1 RNA in Blood and Lymphoid Tissue: A Randomized Trial of Double Versus Triple Therapy

Autor: Milos Opravil, Marek Fischer, Werner Huber, Stefano Bassetti, Pietro Vernazza, Patrizio Lorenzi, Peter Ott, Marlyse C. Knuchel, Richard W. Cone, Leslie R. Bisset, Ruedi Lüthy, Rainer Weber, Malgorzata Roos

Publikováno v: JAIDS Journal of Acquired Immune Deficiency Syndromes. 23:17-25

To assess the effects of early initiation of antiretroviral therapy on cell-free and cell-associated viral load in blood and lymphoid tissue, we performed a randomized, open-label, multicenter trial comparing a double (zidovudine + lamivudine) and tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16cb25592efbf3640f2b6dc90c1fd49
https://doi.org/10.1097/00126334-200001010-00003

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Simple monitoring of antiretroviral therapy with a signal-amplification-boosted HIV-1 p24 antigen assay with heat-denatured plasma

Autor: Jörg Schüpbach, Madeleine Rothen, Peter Grob, Leslie R. Bisset, Ruedi Lüthy, Milos Opravil, Zuzana Tomasik, Jürg Böni

Publikováno v: AIDS. 11:F47-F52

OBJECTIVE: Virus load determination has become indispensable for the management of HIV patients, but depends on expensive assays of a low throughput. We evaluated whether a highly improved HIV-1 p24 antigen detection procedure which involves heat-med

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25c52a48f195e85ee9739eb972d5887
https://doi.org/10.1097/00002030-199706000-00001

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Change in circulating levels of the chemokines macrophage inflammatory proteins 1α and 1β, RANTES, monocyte chemotactic protein-1 and interleukin-16 following treatment of severely immunodeficient HIV-infected individuals with indinavir

Autor: Madeleine Rothen, Leslie R. Bisset, Milos Opravil, Helen I. Joller-Jemelka, Rolf W. Dubs, Peter Grob

Publikováno v: AIDS. 11:485-491

Objective To evaluate the in vivo relationship between HIV replication and circulating levels of the chemokines macrophage inflammatory protein (MIP)-1 alpha, MIP-1 beta, RANTES (acronym for Regulated upon Activation, Normal T-cell Expressed and pres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84113be9250256cbab37bf6f3fab65f4
https://doi.org/10.1097/00002030-199704000-00012

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