Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Leslie R Bridges"'
Autor:
Leslie R. Bridges
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Recently, electron cryo-microscopy (cryo-EM) maps of fibrils from the brains of mice and hamsters with five infectious scrapie strains have been published and deposited in the electron microscopy data bank (EMDB). As noted by the primary aut
Externí odkaz:
https://doaj.org/article/85a43937f03141cb8de46ed976c732af
Autor:
Marta Viana-Pereira, Alicia Lee, Sergey Popov, Dorine A Bax, Safa Al-Sarraj, Leslie R Bridges, João N Stávale, Darren Hargrave, Chris Jones, Rui M Reis
Publikováno v:
PLoS ONE, Vol 6, Iss 5, p e20588 (2011)
High grade gliomas (HGG) are one of the leading causes of cancer-related deaths in children, and there is increasing evidence that pediatric HGG may harbor distinct molecular characteristics compared to adult tumors. We have sought to clarify the rol
Externí odkaz:
https://doaj.org/article/77ef1dfc3e6541fab41b35b6ce6f9659
Autor:
Anan Shtaya, Leslie R. Bridges, Margaret M. Esiri, Joanne Lam‐Wong, James A. R. Nicoll, Delphine Boche, Atticus H. Hainsworth
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1465-1479 (2019)
Abstract Objective Spontaneous intracerebral hemorrhage (ICH) is the commonest form of hemorrhagic stroke and is associated with a poor prognosis. Neurosurgical removal of intracerebral hematoma has limited benefit and no pharmacotherapies are availa
Externí odkaz:
https://doaj.org/article/4801f1cc2977426ba54be23a61dcdd38
Autor:
Adam Anad, Miriam K Barker, Jessica A Katanga, Konstantinos Arfanakis, Leslie R Bridges, Margaret M Esiri, Jeremy D Isaacs, Sonja Prpar Mihevc, Anthony C Pereira, Julie A Schneider, Atticus H Hainsworth
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 81:182-192
Cerebral small vessel disease (SVD) causes lacunar stroke and vascular cognitive impairment in older people. The pathogenic pathways from vessel pathology to parenchymal damage in SVD are unknown. Neurofilaments are axonal structural proteins. Neurof
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00719e25c03042e5be1914b7a5441f85
https://doi.org/10.1093/jnen/nlab134
https://doi.org/10.1093/jnen/nlab134
Autor:
Leslie R. Bridges
Fibrils from brains of patients with Alzheimer’s disease1–5, Parkinson’s disease6, amyotrophic lateral sclerosis7and other neurodegenerations3,4,8–18contain unknown molecules. Extra densities (EDs), containing these unknown molecules, are ava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd46a3a9dca22e601e3291291f6d2470
https://doi.org/10.1101/2023.02.01.526613
https://doi.org/10.1101/2023.02.01.526613
Autor:
Hildegard Dohmen, Hans-Georg Wirsching, Andreas von Deimling, Marco Stein, John G. Golfinos, Thomas Hielscher, Annika K. Wefers, Jens Schittenhelm, Fay E. A. Greenway, Areeba Patel, David T.W. Jones, Christian Mawrin, Chandra N. Sen, Elisabeth J. Rushing, Katrin Lamszus, Christine Jungk, Christina Blume, Anna S. Berghoff, Annekathrin Reinhardt, Jürgen Hench, Peter Baumgarten, Martin Sill, Till Acker, Daniel Schrimpf, Damian Stichel, Wolfgang Wick, David E. Reuss, Matija Snuderl, Miriam Ratliff, Marian Christoph Neidert, Michael Platten, Leslie R. Bridges, Sybren L. N. Maas, Abigail K. Suwala, Manfred Westphal, Stefan M. Pfister, Helin Dogan, Guido Reifenberger, Patrick N. Harter, Zane Jaunmuktane, Gerhard Jungwirth, Conor Grady, Severina Leu, Felix Sahm, Melanie Bewerunge-Hudler, Andreas Unterberg, Philipp Sievers, Nima Etminan, Michael Weller, Ralf Ketter, Jonathan Serrano, Matthias Preusser, Sebastian Brandner, Philipp Euskirchen, Christel Herold-Mende, Franz Ricklefs, Timothy L. Jones, Kenneth Aldape, Stephan Frank, Daniel Hänggi
Publikováno v:
Journal of Clinical Oncology. 39:3839-3852
PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from benign to highly aggressive, ultimately fatal courses. Reliable identification of risk of progression for individual patients is of pivotal impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474a502452da1de019ef82854c109014
https://doi.org/10.1200/jco.21.00784
https://doi.org/10.1200/jco.21.00784
Autor:
Simon Stapleton, Leslie R. Bridges, Francis G. Johnston, Anan Shtaya, Samantha Hettige, Robert Iorga
Publikováno v:
Neurosurgical Review. 45:103-118
Cauda equina paragangliomas are rare benign extra-adrenal neuroendocrine tumours arising from the neural crest cells associated with autonomic ganglia. These tumours are often mistaken preoperatively for ependymomas or schwannomas. Patients present w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e645b4f5cbae745de6819b95e18728e7
https://doi.org/10.1007/s10143-021-01565-7
https://doi.org/10.1007/s10143-021-01565-7
Autor:
Martin Sill, Jessica C Pickles, Abigail F Peary, Mark Kristiansen, David T.W. Jones, Steven C. Clifford, Dariusz Ladon, David A Hilton, Darren Hargrave, SA Yasin, David Capper, Nitika Rathi, Aimee Avery, Olumide Ogunbiyi, Amy R Fairchild, Marie Edwards, Lawrence Doey, Kathreena M Kurian, G. Alistair Lammie, Chris Jones, Antonia Torgersen, Ashirwad Merve, Lorelle Brownlee, Rebecca M Hill, James A. R. Nicoll, Yura Grabovska, Azzam Ismail, Frances Rae, Thomas S. Jacques, Daniel Williamson, Aruna Chakrabarty, Clara Limback-Stanic, Tabitha Bloom, Safa Al-Sarraj, Jamie Gonzalez Zapata, Catherine Rowe, Leslie R. Bridges, Stefan M. Pfister, Carryl Dryden, Saira W. Ahmed, Khaja Syed, Lisa Wilkhu, Colin Smith, Thomas J Stone, Paul N Johns, Andreas von Deimling, Matthew Clarke, Clare Mitchell, Jane Chalker
Publikováno v:
Pickles, J C, Fairchild, A R, Stone, T J, Brownlee, L, Merve, A, Yasin, S A, Avery, A, Ahmed, S W, Ogunbiyi, O, Gonzalez Zapata, J, Peary, A F, Edwards, M, Wilkhu, L, Dryden, C, Ladon, D, Kristiansen, M, Rowe, C, Kurian, K M, Nicoll, J A R, Mitchell, C, Bloom, T, Hilton, D A, Al-Sarraj, S, Doey, L, Johns, P N, Bridges, L R, Chakrabarty, A, Ismail, A, Rathi, N, Syed, K, Lammie, G A, Limback-Stanic, C, Smith, C, Torgersen, A, Rae, F, Hill, R M, Clifford, S C, Grabovska, Y, Williamson, D, Clarke, M, Jones, C, Capper, D, Sill, M, von Deimling, A, Pfister, S M, Jones, D T W, Hargrave, D, Chalker, J & Jacques, T S 2020, ' DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment : a population-based study ', The Lancet Child and Adolescent Health, vol. 4, no. 2, pp. 121-130 . https://doi.org/10.1016/S2352-4642(19)30342-6
Summary Background Marked variation exists in the use of genomic data in tumour diagnosis, and optimal integration with conventional diagnostic technology remains uncertain despite several studies reporting improved diagnostic accuracy, selection for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83379610827dcf35a669159c2f2b68f3
https://doi.org/10.1016/s2352-4642(19)30342-6
https://doi.org/10.1016/s2352-4642(19)30342-6
Autor:
Michael Karremann, Olaf Witt, Tabitha Bloom, Winand N.M. Dinjens, Felipe Andreiuolo, Michael Farrell, Scott Newman, Simone Hettmer, James Dalton, Leslie R. Bridges, Jens Schittenhelm, Martin Ebinger, Thomas S. Jacques, Francesca Diomedi-Camassei, Dominik Sturm, Jane Chalker, Matija Snuderl, David W. Ellison, Paula Proszek, Irene Slavc, Matthias A. Karajannis, Giovanna Stefania Colafati, Louise Howell, Christine Haberler, Simon Bailey, Barbara C. Worst, David A. Solomon, Andrew J. Martin, Stefan M. Pfister, Maria Vinci, Ho Keung Ng, Kelly Haupfear, Mellissa Maybury, Stephen Gilheeney, Bassel Zebian, Martin Sill, David T.W. Jones, Pablo Hernáiz Driever, Martin U. Schuhmann, Angela Mastronuzzi, Jessica K.R. Boult, Matthew Clarke, Rachael Natrajan, Kornelius Kerl, Lawrence Doey, Alex Virasami, Andrey Korshunov, Christof M. Kramm, Jane Cryan, David E. Kram, Timothy E.G. Hassall, Debbie Hughes, Claire Mitchell, Chris Jones, Monika A. Davare, Evelina Miele, Safa Al-Sarraj, Sara Temelso, Catherine Rowe, Suzanne J. Baker, Sergey Popov, Torsten Pietsch, Matthew D. Wood, Roger J. Packer, Lynley V. Marshall, Michael Capra, Valeria Molinari, Diana Carvalho, Marc Zuckermann, Andreas von Deimling, Uwe Kordes, Kathreena M Kurian, Shani Caspi, Ira J. Dunkel, Wilda Orisme, Ulrich Schüller, Claire Cairns, Matthias Preusser, Kristian Aquilina, Petter Brandal, Stephen Lowis, Iris Stoler, Christopher Chandler, Lissa C. Baird, Marc K. Rosenblum, Ji Wen, Felix Sahm, Barbara Faganel Kotnik, Stephen Crosier, Mara Popović, Andrea Carai, Lotte Hiddingh, Thale Kristin Olsen, Fernando Carceller, Simon P. Robinson, Maria Tsoli, Ruth G. Tatevossian, Anna Burford, Mike Hubank, Elisa Izquierdo, Tejus Bale, David Capper, Andrew S. Moore, David S. Ziegler, Amy R Fairchild, Aimee Avery, Alan Mackay, Jessica C Pickles, Mark Kristiansen, Jeffrey Knipstein, Darren Hargrave, Mark J. Cowley, Tobey J. MacDonald, Britta Ismer
Publikováno v:
Cancer Discovery, 10(7), 942-963. American Association for Cancer Research Inc.
Clarke, M, Mackay, A, Ismer, B, Pickles, J C, Tatevossian, R G, Newman, S, Bale, T A, Stoler, I, Izquierdo, E, Temelso, S, Carvalho, D M, Molinari, V, Burford, A, Howell, L, Virasami, A, Fairchild, A R, Avery, A, Chalker, J, Kristiansen, M, Haupfear, K, Dalton, J D, Orisme, W, Wen, J, Hubank, M, Kurian, K M, Rowe, C & Lowis, S P 2020, ' Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes ', Cancer Discovery . https://doi.org/10.1158/2159-8290.CD-19-1030
Cancer Discov
Clarke, M, Mackay, A, Ismer, B, Pickles, J C, Tatevossian, R G, Newman, S, Bale, T A, Stoler, I, Izquierdo, E, Temelso, S, Carvalho, D M, Molinari, V, Burford, A, Howell, L, Virasami, A, Fairchild, A R, Avery, A, Chalker, J, Kristiansen, M, Haupfear, K, Dalton, J D, Orisme, W, Wen, J, Hubank, M, Kurian, K M, Rowe, C & Lowis, S P 2020, ' Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes ', Cancer Discovery . https://doi.org/10.1158/2159-8290.CD-19-1030
Cancer Discov
Infant high-grade gliomas appear clinically distinct from their counterparts in older children, indicating that histopathologic grading may not accurately reflect the biology of these tumors. We have collected 241 cases under 4 years of age, and carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::149d27d0bc97b5ac929baad5a7056e03
https://pure.eur.nl/en/publications/16cbcb48-5514-46b8-9f3b-2156ff9b5540
https://pure.eur.nl/en/publications/16cbcb48-5514-46b8-9f3b-2156ff9b5540
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba78fbf3cf60daaf586766be22a9dcef
https://doi.org/10.1530/endoabs.77.p220
https://doi.org/10.1530/endoabs.77.p220