RNA as a component of scrapie fibrils

Autor: Leslie R. Bridges

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Abstract Recently, electron cryo-microscopy (cryo-EM) maps of fibrils from the brains of mice and hamsters with five infectious scrapie strains have been published and deposited in the electron microscopy data bank (EMDB). As noted by the primary aut

Externí odkaz: https://doaj.org/article/85a43937f03141cb8de46ed976c732af

Vasculocentric Axonal NfH in Small Vessel Disease

Autor: Adam Anad, Miriam K Barker, Jessica A Katanga, Konstantinos Arfanakis, Leslie R Bridges, Margaret M Esiri, Jeremy D Isaacs, Sonja Prpar Mihevc, Anthony C Pereira, Julie A Schneider, Atticus H Hainsworth

Publikováno v: Journal of Neuropathology & Experimental Neurology. 81:182-192

Cerebral small vessel disease (SVD) causes lacunar stroke and vascular cognitive impairment in older people. The pathogenic pathways from vessel pathology to parenchymal damage in SVD are unknown. Neurofilaments are axonal structural proteins. Neurof

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00719e25c03042e5be1914b7a5441f85
https://doi.org/10.1093/jnen/nlab134

Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated

Autor: Hildegard Dohmen, Hans-Georg Wirsching, Andreas von Deimling, Marco Stein, John G. Golfinos, Thomas Hielscher, Annika K. Wefers, Jens Schittenhelm, Fay E. A. Greenway, Areeba Patel, David T.W. Jones, Christian Mawrin, Chandra N. Sen, Elisabeth J. Rushing, Katrin Lamszus, Christine Jungk, Christina Blume, Anna S. Berghoff, Annekathrin Reinhardt, Jürgen Hench, Peter Baumgarten, Martin Sill, Till Acker, Daniel Schrimpf, Damian Stichel, Wolfgang Wick, David E. Reuss, Matija Snuderl, Miriam Ratliff, Marian Christoph Neidert, Michael Platten, Leslie R. Bridges, Sybren L. N. Maas, Abigail K. Suwala, Manfred Westphal, Stefan M. Pfister, Helin Dogan, Guido Reifenberger, Patrick N. Harter, Zane Jaunmuktane, Gerhard Jungwirth, Conor Grady, Severina Leu, Felix Sahm, Melanie Bewerunge-Hudler, Andreas Unterberg, Philipp Sievers, Nima Etminan, Michael Weller, Ralf Ketter, Jonathan Serrano, Matthias Preusser, Sebastian Brandner, Philipp Euskirchen, Christel Herold-Mende, Franz Ricklefs, Timothy L. Jones, Kenneth Aldape, Stephan Frank, Daniel Hänggi

Publikováno v: Journal of Clinical Oncology. 39:3839-3852

PURPOSE Meningiomas are the most frequent primary intracranial tumors. Patient outcome varies widely from benign to highly aggressive, ultimately fatal courses. Reliable identification of risk of progression for individual patients is of pivotal impo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474a502452da1de019ef82854c109014
https://doi.org/10.1200/jco.21.00784

DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study

Autor: Martin Sill, Jessica C Pickles, Abigail F Peary, Mark Kristiansen, David T.W. Jones, Steven C. Clifford, Dariusz Ladon, David A Hilton, Darren Hargrave, SA Yasin, David Capper, Nitika Rathi, Aimee Avery, Olumide Ogunbiyi, Amy R Fairchild, Marie Edwards, Lawrence Doey, Kathreena M Kurian, G. Alistair Lammie, Chris Jones, Antonia Torgersen, Ashirwad Merve, Lorelle Brownlee, Rebecca M Hill, James A. R. Nicoll, Yura Grabovska, Azzam Ismail, Frances Rae, Thomas S. Jacques, Daniel Williamson, Aruna Chakrabarty, Clara Limback-Stanic, Tabitha Bloom, Safa Al-Sarraj, Jamie Gonzalez Zapata, Catherine Rowe, Leslie R. Bridges, Stefan M. Pfister, Carryl Dryden, Saira W. Ahmed, Khaja Syed, Lisa Wilkhu, Colin Smith, Thomas J Stone, Paul N Johns, Andreas von Deimling, Matthew Clarke, Clare Mitchell, Jane Chalker

Publikováno v: Pickles, J C, Fairchild, A R, Stone, T J, Brownlee, L, Merve, A, Yasin, S A, Avery, A, Ahmed, S W, Ogunbiyi, O, Gonzalez Zapata, J, Peary, A F, Edwards, M, Wilkhu, L, Dryden, C, Ladon, D, Kristiansen, M, Rowe, C, Kurian, K M, Nicoll, J A R, Mitchell, C, Bloom, T, Hilton, D A, Al-Sarraj, S, Doey, L, Johns, P N, Bridges, L R, Chakrabarty, A, Ismail, A, Rathi, N, Syed, K, Lammie, G A, Limback-Stanic, C, Smith, C, Torgersen, A, Rae, F, Hill, R M, Clifford, S C, Grabovska, Y, Williamson, D, Clarke, M, Jones, C, Capper, D, Sill, M, von Deimling, A, Pfister, S M, Jones, D T W, Hargrave, D, Chalker, J & Jacques, T S 2020, ' DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment : a population-based study ', The Lancet Child and Adolescent Health, vol. 4, no. 2, pp. 121-130 . https://doi.org/10.1016/S2352-4642(19)30342-6

Summary Background Marked variation exists in the use of genomic data in tumour diagnosis, and optimal integration with conventional diagnostic technology remains uncertain despite several studies reporting improved diagnostic accuracy, selection for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83379610827dcf35a669159c2f2b68f3
https://doi.org/10.1016/s2352-4642(19)30342-6

Multiple Cell Line Pituitary Adenoma associated with PIT-1 and TPIT lineage cells resulting in acromegaly with ACTH dependent Cushing’s: a case report

Autor: Kyaw Ye, Gul Bano, Andrew J. Martin, Leslie R. Bridges, Hareesh Joshi

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ba78fbf3cf60daaf586766be22a9dcef
https://doi.org/10.1530/endoabs.77.p220