Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Leslie R, Harrold"'
Autor:
Leslie R. Harrold, Keith Wittstock, Sheila Kelly, Xue Han, Joe Zhuo, Amy Schrader, Nicole Middaugh, Page C. Moore, Vadim Khaychuk
Publikováno v:
Advances in Rheumatology, Vol 64, Iss 1, Pp 1-11 (2024)
Abstract Background The HLA-DRB1 shared epitope (SE) is a risk factor for the development of rheumatoid arthritis (RA) and the production of anti-citrullinated protein antibodies (ACPAs) in RA patients. Our objective was to examine the real-world eff
Externí odkaz:
https://doaj.org/article/fe935ce0ec0c4b219778878a6c299874
Autor:
Leslie R. Harrold, Patrick Zueger, W. Benjamin Nowell, Taylor Blachley, Amy Schrader, Paul R. Lakin, David Curtis, Laura Stradford, Shilpa Venkatachalam, Namita Tundia, Pankaj A. Patel
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 6, Pp 1519-1533 (2023)
Abstract Introduction The impact of upadacitinib on rheumatoid arthritis (RA) symptoms was evaluated during the first 12 weeks of treatment via patient-reported outcomes (PROs) using a mobile health application (app). Methods Participating rheumatolo
Externí odkaz:
https://doaj.org/article/dd8856bcc29541ef9868140fa069a7a6
Autor:
Jeffrey R Curtis, Leslie R Harrold, Susan J Blalock, Liana Fraenkel, Carole Wiedmeyer, Betty Hsiao, Julie S Downs, Mandy Lanyon, William Benjamin Nowell, Shilpa Venkatachalam, Mark T Patterson, Kelly Gavigan, Laura Stradford, Danielle Ali
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Objective Uptake of treat-to-target (TTT) strategies for rheumatoid arthritis (RA) management is low. Our objective was to understand the heterogeneity in patients’ conceptualisation of RA treatment to inform interventions improving TTT uptake.Desi
Externí odkaz:
https://doaj.org/article/1328366474d24d87a665883883b0dbcb
Comparative Effectiveness of Abatacept vs. Tofacitinib in Rheumatoid Arthritis Patients who are CCP+
Autor:
Leslie R. Harrold, Keith Wittstock, Sheila Kelly, Xue Han, Ying Shan, Lin Guo, Page C. Moore, Vadim Khaychuk
Publikováno v:
Rheumatology and Therapy, Vol 10, Iss 3, Pp 575-587 (2023)
Abstract Introduction Currently there is limited data to drive clinical decision making regarding the choice of biologic/targeted synthetic disease-modifying antirheumatic drugs (DMARD); thus, head-to-head comparisons are needed to help guide prescri
Externí odkaz:
https://doaj.org/article/242a5d4c95ca444e82ba8baa68442026
Autor:
Betty Hsiao, Julie Downs, Mandy Lanyon, Susan J. Blalock, Jeffrey R. Curtis, Leslie R. Harrold, William Benjamin Nowell, Carole Wiedmeyer, Shilpa Venkatachalam, Liana Fraenkel
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 8, Pp 700-710 (2022)
Objective Despite proven benefits, less than half of patients with rheumatoid arthritis (RA) are treated using a treat‐to‐target (TTT) strategy. Our objective was to identify critical discrepancies between rheumatologist and patient mental models
Externí odkaz:
https://doaj.org/article/3d2f2537d04e487ca1bbb9239323db74
Autor:
Kazuki Yoshida, Leslie R. Harrold, Nicole Middaugh, Hongshu Guan, Scott Stryker, Elaine Karis, Daniel H. Solomon
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 7, Pp 587-595 (2022)
Objective It is unknown how the relationship between disease activity in rheumatoid arthritis (RA) and cardiovascular (CV) events may change over time. We examined the potentially time‐varying association of RA disease activity to CV events. Method
Externí odkaz:
https://doaj.org/article/6b9bd168eb9446ac9f362d18dcc241bf
Autor:
Maria I. Danila, Lang Chen, Eric M. Ruderman, Justin K. Owensby, Ronan O’Beirne, Joshua A. Melnick, Leslie R. Harrold, David Curtis, W. Benjamin Nowell, Jeffrey R. Curtis
Publikováno v:
ACR Open Rheumatology, Vol 4, Iss 4, Pp 279-287 (2022)
Objective This study’s objective was to test whether an online video intervention discussing appropriate treatment escalation improves willingness to change treatment in people living with rheumatoid arthritis (RA). Methods We conducted a controlle
Externí odkaz:
https://doaj.org/article/854aa644f61146d49b75966861b67ded
Autor:
Leslie R. Harrold, Heather J. Litman, Sean E. Connolly, Evo Alemao, Sheila Kelly, Sabrina Rebello, Winnie Hua, Joel M. Kremer
Publikováno v:
Rheumatology and Therapy, Vol 6, Iss 2, Pp 217-230 (2019)
Abstract Introduction Anti-citrullinated protein antibodies (ACPAs) are highly specific serological biomarkers that are indicative of a poor prognosis in patients with rheumatoid arthritis (RA). The effectiveness of biologic disease-modifying antirhe
Externí odkaz:
https://doaj.org/article/812cba2a5c4548318fedf2a8c36e6960
Publikováno v:
Rheumatology and Therapy, Vol 5, Iss 2, Pp 507-523 (2018)
Abstract Introduction Controlled clinical studies have shown that the efficacy of tocilizumab (TCZ) monotherapy is superior to that of tumor necrosis factor inhibitor (TNFi) monotherapy and comparable to that of TCZ plus methotrexate (MTX) for the tr
Externí odkaz:
https://doaj.org/article/2605c3fffa824eb6aeb02cbd9298716a
Autor:
Leslie R. Harrold, Heather J. Litman, Katherine C. Saunders, Kimberly J. Dandreo, Bernice Gershenson, Jeffrey D. Greenberg, Robert Low, Jeffrey Stark, Robert Suruki, Srihari Jaganathan, Joel M. Kremer, Mohamed Yassine
Publikováno v:
Arthritis Research & Therapy, Vol 20, Iss 1, Pp 1-11 (2018)
Abstract Background Registry studies provide a valuable source of comparative safety data for tumor necrosis factor inhibitors (TNFi) used in rheumatoid arthritis (RA), but they are subject to channeling bias. Comparing safety outcomes without accoun
Externí odkaz:
https://doaj.org/article/b0086cce10b7407b95e3ca6a90f94d2f