Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Leslie Nangle"'
Autor:
Luke Burman, Yeeting E. Chong, Sherie Duncan, Anders Klaus, Kaitlyn Rauch, Kristina Hamel, Karine Hervé, Stephanie Pfaffen, David W. Collins, Kevin Heyries, Leslie Nangle, Carl Hansen, David J. King
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
The autoimmune disease known as Jo-1 positive anti-synthetase syndrome (ASS) is characterized by circulating antibody titers to histidyl-tRNA synthetase (HARS), which may play a role in modulating the non-canonical functions of HARS. Monoclonal antib
Externí odkaz:
https://doaj.org/article/565e85380f9c49588adad53d2c7d3099
Autor:
Elisabeth C. Mertsching, Jeanette Ampudia, Ryan Adams, Sanna Rosengren, Leslie Nangle, John Mendlein, Andrea Cubitt, Fred Ramsdell, Kathy Ogilvie, David King
Publikováno v:
The Journal of Immunology. 200:112.3-112.3
Histidyl-tRNA synthetase (HARS) is the autoantigen target of Jo-1 antibodies, which occur in the major form of anti-synthetase syndrome. These patients are characterized by an autoimmune myositis and interstitial lung disease. Circulating extracellul