Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Leslie M. Meenderink"'
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100998- (2021)
Summary: A key facet of epithelial differentiation is the assembly of actin-based protrusions known as microvilli, which amplify apical membrane surface area for various cell functions. To probe mechanisms of microvillus assembly, we developed a prot
Externí odkaz:
https://doaj.org/article/2ec10d5a87bf47ab9966f03730a87156
Autor:
Caroline S. Cencer, Jennifer B. Silverman, Leslie M. Meenderink, Evan S. Krystofiak, Bryan A. Millis, Matthew J. Tyska
Publikováno v:
bioRxiv
SUMMARYDifferentiated transporting epithelial cells present an extensive apical array of microvilli – a “brush border” – where neighboring microvilli are linked together by intermicrovillar adhesion complexes (IMACs) composed of protocadherin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa2f73b2fe937ce148aae6e1ab985e11
https://doi.org/10.1101/2023.03.08.531705
https://doi.org/10.1101/2023.03.08.531705
Autor:
David G. Harrison, Tarek S. Absi, Simon Mallal, Rama Gangula, Renu Virmani, Daniella T Fuller, Joshua A. Beckman, Meena S. Madhur, Chike O. Abana, Leslie M. Meenderink, Cathy A. Jenkins, Kenji Kawai, Christian M Warren, Rita M. Smith, Tecla M Temu, Liang Guo, Curtis L. Gabriel, Aloke V. Finn, Alexander Gelbard, Yan Ru Su, John R. Koethe, Samuel S Bailin, Matthew J. Tyska, Celestine N. Wanjalla, Spyros A. Kalams, Mona Mashayekhi
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41:1459-1473
Objective: Persons with HIV have double the risk of developing cardiovascular disease compared with the general population. A persistent and heightened immune response to cytomegalovirus coinfection may be one contributing factor, but the relationshi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0ba623f2abad0010ec9f5e9ba3d8afe
https://doi.org/10.1161/atvbaha.120.315786
https://doi.org/10.1161/atvbaha.120.315786
Publikováno v:
Molecular Biology of the Cell
Apical microvilli are critical for the homeostasis of transporting epithelia, yet mechanisms that control the assembly and morphology of these protrusions remain poorly understood. Previous studies in intestinal epithelial cell lines suggested a role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95143e1806fd9f22729e3da1af10637c
http://europepmc.org/articles/PMC6743356
http://europepmc.org/articles/PMC6743356
Autor:
Celestine N, Wanjalla, Mona, Mashayekhi, Samuel, Bailin, Curtis L, Gabriel, Leslie M, Meenderink, Tecla, Temu, Daniella T, Fuller, Liang, Guo, Kenji, Kawai, Renu, Virmani, Cathy, Jenkins, Chike O, Abana, Christian M, Warren, Rama, Gangula, Rita, Smith, Meena S, Madhur, Aloke V, Finn, Alexander H, Gelbard, Yan Ru, Su, Matthew J, Tyska, Spyros A, Kalams, David G, Harrison, Simon A, Mallal, Tarek S, Absi, Joshua A, Beckman, John R, Koethe
Publikováno v:
Arterioscler Thromb Vasc Biol
OBJECTIVE: Persons with human immunodeficiency virus (HIV) have double the risk of developing cardiovascular disease (CVD) compared to the general population. A persistent and heightened immune response to cytomegalovirus (CMV) co-infection may be on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85756640daadb1a4bdbec6572753510e
https://pubmed.ncbi.nlm.nih.gov/33567869
https://pubmed.ncbi.nlm.nih.gov/33567869
Epithelial brush borders are large arrays of microvilli that enable efficient solute uptake from luminal spaces. In the context of the intestinal tract, brush border microvilli drive functions that are critical for physiological homeostasis, includin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2ba3bee6e39748dc337a22f5347cec8
https://doi.org/10.1101/2020.05.01.072389
https://doi.org/10.1101/2020.05.01.072389
Autor:
Leslie M Meenderink, Larisa M Ryzhova, Dominique M Donato, Daniel F Gochberg, Irina Kaverina, Steven K Hanks
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13412 (2010)
The docking protein p130Cas is a prominent Src substrate found in focal adhesions (FAs) and is implicated in regulating critical aspects of cell motility including FA disassembly and protrusion of the leading edge plasma membrane. To better understan
Externí odkaz:
https://doaj.org/article/73af04ccfa1445f9a2376a85019ad108
Autor:
Caroline S. Cencer, Isabella M. Gaeta, Matthew J. Tyska, Leslie M. Meenderink, Meagan M. Postema
Publikováno v:
Curr Biol
Microvilli are actin-bundle-supported surface protrusions that play essential roles in diverse epithelial functions. To develop our understanding of microvilli biogenesis, we used live imaging to directly visualize protrusion growth at early stages o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7052da36e27baa17aa17af7ecac9f0
https://doi.org/10.1016/j.cub.2021.04.012
https://doi.org/10.1016/j.cub.2021.04.012
Autor:
Leslie M. Meenderink, Matthew J. Tyska
SUMMARYDuring differentiation, transporting epithelial cells generate large arrays of microvilli known as a brush borders to enhance functional capacity. To develop our understanding of brush border formation, we used live cell imaging to visualize a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e506e63438636fae2991737af2eadcc2
Autor:
Bryan A. Millis, Caroline S. Cencer, Matthew J. Tyska, Meagan M. Postema, Leslie M. Meenderink, Evan S. Krystofiak, Isabella M. Gaeta, Colbie R. Chinowsky
Publikováno v:
Developmental Cell. 50:545-556.e4
Summary Transporting epithelial cells generate arrays of microvilli, known as a brush border, to enhance functional capacity. To understand brush border formation, we used live cell imaging to visualize apical remodeling early in this process. Striki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c857338737776508ae83f56807479c7
https://doi.org/10.1016/j.devcel.2019.07.008
https://doi.org/10.1016/j.devcel.2019.07.008