Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Leslie M Mayo Smith"'
Autor:
Richelle C. Charles, Meagan Kelly, Jenny M. Tam, Aklima Akter, Motaher Hossain, Kamrul Islam, Rajib Biswas, Mohammad Kamruzzaman, Fahima Chowdhury, Ashraful I. Khan, Daniel T. Leung, Ana Weil, Regina C. LaRocque, Taufiqur Rahman Bhuiyan, Atiqur Rahman, Leslie M. Mayo-Smith, Rachel L. Becker, Jatin M. Vyas, Christina S. Faherty, Kourtney P. Nickerson, Samantha Giffen, Alaina S. Ritter, Matthew K. Waldor, Peng Xu, Pavol Kováč, Stephen B. Calderwood, Robert C. Kauffman, Jens Wrammert, Firdausi Qadri, Jason B. Harris, Edward T. Ryan
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT The mechanism of protection against cholera afforded by previous illness or vaccination is currently unknown. We have recently shown that antibodies targeting O-specific polysaccharide (OSP) of Vibrio cholerae correlate highly with protectio
Externí odkaz:
https://doaj.org/article/d099d08206104bbf8c76536df01b508a
Autor:
Motaher Hossain, Kamrul Islam, Meagan Kelly, Leslie M Mayo Smith, Richelle C Charles, Ana A Weil, Taufiqur Rahman Bhuiyan, Pavol Kováč, Peng Xu, Stephen B Calderwood, Jakub K Simon, Wilbur H Chen, Michael Lock, Caroline E Lyon, Beth D Kirkpatrick, Mitchell Cohen, Myron M Levine, Marc Gurwith, Daniel T Leung, Andrew S Azman, Jason B Harris, Firdausi Qadri, Edward T Ryan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007874 (2019)
BackgroundAntibodies targeting O-specific polysaccharide (OSP) of Vibrio cholerae may protect against cholera; however, little is known about this immune response in infected immunologically naïve humans.MethodologyWe measured serum anti-OSP antibod
Externí odkaz:
https://doaj.org/article/916ab507d03948078640a876d62ccc61
Autor:
Brie Falkard, Richelle C Charles, Wilfredo R Matias, Leslie M Mayo-Smith, J Gregory Jerome, Evan S Offord, Peng Xu, Pavol Kováč, Edward T Ryan, Firdausi Qadri, Molly F Franke, Louise C Ivers, Jason B Harris
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0007057 (2019)
The bivalent killed whole-cell oral cholera vaccine (BivWC) is being increasingly used to prevent cholera. The presence of O-antigen-specific memory B cells (MBC) has been associated with protective immunity against cholera, yet MBC responses have no
Externí odkaz:
https://doaj.org/article/0adc26f056464a42bd6f6d74bd87391b
Autor:
Kamrul Islam, Motaher Hossain, Meagan Kelly, Leslie M Mayo Smith, Richelle C Charles, Taufiqur Rahman Bhuiyan, Pavol Kováč, Peng Xu, Regina C LaRocque, Stephen B Calderwood, Jakub K Simon, Wilbur H Chen, Douglas Haney, Michael Lock, Caroline E Lyon, Beth D Kirkpatrick, Mitchell Cohen, Myron M Levine, Marc Gurwith, Jason B Harris, Firdausi Qadri, Edward T Ryan
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006376 (2018)
BACKGROUND:Cholera is an acute voluminous dehydrating diarrheal disease caused by toxigenic strains of Vibrio cholerae O1 and occasionally O139. A growing body of evidence indicates that immune responses targeting the O-specific polysaccharide (OSP)
Externí odkaz:
https://doaj.org/article/5a7a697cf70e4170a1b24a53b409d81b
Autor:
Wilfredo R Matias, Fabrice E Julceus, Cademil Abelard, Leslie M Mayo-Smith, Molly F Franke, Jason B Harris, Louise C Ivers
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0186710 (2017)
BACKGROUND:Rapid diagnostic tests (RDT) for cholera are promising tools for detecting cholera in areas with limited laboratory infrastructure. However, evidence on the characteristics of the many available RDTs is scarce, and their use has been limit
Externí odkaz:
https://doaj.org/article/1878ae85806a4b3cbde92b50731a98d9
Autor:
Robert C. Kauffman, Taufiqur R. Bhuiyan, Rie Nakajima, Leslie M. Mayo-Smith, Rasheduzzaman Rashu, Mohammad Rubel Hoq, Fahima Chowdhury, Ashraful Islam Khan, Atiqur Rahman, Siddhartha K. Bhaumik, Levelle Harris, Justin T. O'Neal, Jessica F. Trost, Nur Haq Alam, Algis Jasinskas, Emmanuel Dotsey, Meagan Kelly, Richelle C. Charles, Peng Xu, Pavol Kováč, Stephen B. Calderwood, Edward T. Ryan, Phillip L. Felgner, Firdausi Qadri, Jens Wrammert, Jason B. Harris
Publikováno v:
mBio, Vol 7, Iss 6 (2016)
ABSTRACT We characterized the acute B cell response in adults with cholera by analyzing the repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) generated from single-cell-sorted plasmablasts. We found that the
Externí odkaz:
https://doaj.org/article/545c93248a4d4ab2b5a66d76c072274b
Autor:
Wilfredo R Matias, Brie Falkard, Richelle C Charles, Leslie M Mayo-Smith, Jessica E Teng, Peng Xu, Pavol Kováč, Edward T Ryan, Firdausi Qadri, Molly F Franke, Louise C Ivers, Jason B Harris
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 6, p e0004753 (2016)
BACKGROUND:The bivalent whole-cell (BivWC) oral cholera vaccine (Shanchol) is effective in preventing cholera. However, evaluations of immune responses following vaccination with BivWC have been limited. To determine whether BivWC induces significant
Externí odkaz:
https://doaj.org/article/c9f7a864d4a249acad2dffd366b6a593
Autor:
Richelle C Charles, Isabelle J Hilaire, Leslie M Mayo-Smith, Jessica E Teng, J Gregory Jerome, Molly F Franke, Amit Saha, Yanan Yu, Paul Kováč, Stephen B Calderwood, Edward T Ryan, Regina C LaRocque, Charles P Almazor, Firdausi Qadri, Louise C Ivers, Jason B Harris
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2828 (2014)
Studies of the immunogenicity of the killed bivalent whole cell oral cholera vaccine, Shanchol, have been performed in historically cholera-endemic areas of Asia. There is a need to assess the immunogenicity of the vaccine in Haiti and other populati
Externí odkaz:
https://doaj.org/article/9c99b1cf9ed64a47821b6b4cb353f804
Autor:
Daniel T. Leung, Regina C. LaRocque, Rachel L. Becker, Firdausi Qadri, Stephen B. Calderwood, Ashraful Islam Khan, Mohammad Kamruzzaman, Kourtney P. Nickerson, Kamrul Islam, Edward T. Ryan, Meagan Kelly, Rajib Biswas, Leslie M. Mayo-Smith, Jenny M. Tam, Motaher Hossain, Samantha R. Giffen, Fahima Chowdhury, Pavol Kováč, Robert C. Kauffman, Alaina S. Ritter, Aklima Akter, Matthew K. Waldor, Richelle C. Charles, Jason B. Harris, Jens Wrammert, Peng Xu, Christina S. Faherty, Ana A. Weil, Taufiqur Rahman Bhuiyan, Atiqur Rahman, Jatin M. Vyas
Publikováno v:
mBio
mBio, Vol 11, Iss 6 (2020)
mBio, Vol 11, Iss 6 (2020)
Cholera is a severe dehydrating illness of humans caused by Vibrio cholerae. V. cholerae is a highly motile bacterium that has a single flagellum covered in lipopolysaccharide (LPS) displaying O-specific polysaccharide (OSP), and V. cholerae motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::743c07becbf36f8442324981e5725e8a
https://doi.org/10.1101/2020.10.08.332551
https://doi.org/10.1101/2020.10.08.332551
Autor:
Edward T. Ryan, Molly F. Franke, Jason B. Harris, Evan S. Offord, Peng Xu, Firdausi Qadri, Louise C. Ivers, Brie Falkard, Richelle C. Charles, Pavol Kováč, Leslie M. Mayo-Smith, J. Gregory Jerome, Wilfredo R. Matias
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0007057 (2019)
PLoS Neglected Tropical Diseases, Vol 13, Iss 1, p e0007057 (2019)
The bivalent killed whole-cell oral cholera vaccine (BivWC) is being increasingly used to prevent cholera. The presence of O-antigen-specific memory B cells (MBC) has been associated with protective immunity against cholera, yet MBC responses have no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824cfd9a65c667aeb73a21ae01fb800f
https://pubmed.ncbi.nlm.nih.gov/30703094
https://pubmed.ncbi.nlm.nih.gov/30703094