Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Leslie Lipka"'
Autor:
Marianne J. H. van Vugt, Julie A. Stone, “Rik” H. J. M. M. De Greef, Ellen S. Snyder, Leslie Lipka, David C. Turner, Anne Chain, Mallika Lala, Mengyao Li, Seth H. Robey, Anna G. Kondic, Dinesh De Alwis, Kapil Mayawala, Lokesh Jain, Tomoko Freshwater
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-8 (2019)
Abstract Background Pembrolizumab is a potent, humanized, monoclonal anti–programmed death 1 antibody that has demonstrated effective antitumor activity and acceptable safety in multiple tumor types. Therapeutic biologics can result in the developm
Externí odkaz:
https://doaj.org/article/3069c7c4e0f64562b9cab9bff16d3f3d
Publikováno v:
Drugs & Aging. 21:1025-1032
To compare the efficacy and safety of statin (HMG-CoA reductase inhibitor) monotherapy versus ezetimibe 10mg plus statin in older and younger adults with primary hypercholesterolaemia. Four multicentre, randomised, double-blind, placebo-controlled, b
Autor:
Alberto Notarbartolo, Lorenzo Melani, Enrico P. Veltri, Philip T. Sager, Ramachandran Suresh, Christie M. Ballantyne, Alexandre LeBeaut, Steven Sun, Leslie Lipka, John Houri
Publikováno v:
Circulation. 107:2409-2415
Background— Despite the established efficacy of statins, many patients do not achieve recommended LDL cholesterol (LDL-C) goals. Contributing factors may be inadequate dosing, increased risk for adverse effects with high-dose monotherapy, and incre
Autor:
Richard Mills, Pabak Mukhopadhyay, Robert Lipetz, Lorenzo Melani, Alexandre LeBeaut, David Hassman, Ramachandran Suresh, Enrico P. Veltri, Leslie Lipka
Publikováno v:
European Heart Journal. 24:717-728
Aims To evaluate the efficacy and safety of ezetimibe 10mg administered with pravastatin in patients with primary hypercholesterolemia. Methods and results After dietary stabilization, 2–12 week screening/washout period, and 4-week, single-blind, p
Autor:
Enrico P. Veltri, Robert Bettis, Lorenzo Melani, Ramachandran Suresh, Thomas J. McGarry, Leslie Lipka, Steven Sun, Michael H. Davidson, Alexandre LeBeaut
Publikováno v:
Journal of the American College of Cardiology. 40:2125-2134
ObjectivesThe purpose of this study was to assess the efficacy and safety of ezetimibe administered with simvastatin in patients with primary hypercholesterolemia.BackgroundDespite the availability of statins, many patients do not achieve lipid targe
Autor:
Alexandre LeBeaut, Ramachandran Suresh, Carlos A. Dujovne, Mark P Ettinger, Leslie Lipka, Bo Yang, Enrico P. Veltri, J. Frederick McNeer
Publikováno v:
The American Journal of Cardiology. 90:1092-1097
The efficacy and safety of ezetimibe, a new cholesterol absorption inhibitor, was evaluated in this randomized, double-blind, placebo-controlled trial of 892 patients with primary hypercholesterolemia. After > or =2 weeks on the National Cholesterol
Autor:
Bo Yang, Carlos A. Dujovne, Harold E. Bays, Leslie Lipka, Robert H Knopp, Margaret Drehobl, L. Mellars, Cynthia Cuffie-Jackson, Sidney Rosenblatt, Paul B Moore, Enrico P. Veltri, Phillip D Toth, Alexandre LeBeaut
Publikováno v:
Clinical Therapeutics. 23:1209-1230
Background: Ezetimibe (SCH 58235) is a novel cholesterol absorption inhibitor that selectively and potently blocks intestinal absorption of dietary and biliary cholesterol. Objective: Data from 2 multicenter, placebo-controlled, double-blind, randomi
Autor:
Leslie Lipka, Evo Alemao, Glenn Davies, Don Yin, John R. Cook, Enrico P. Veltri, Karl J. Krobot, Xavier Badia
Publikováno v:
PharmacoEconomics. 22
Background: Despite the growing use of statins, many hypercholesterolaemic patients fail to reach their lipid goal and remain at elevated risk of coronary heart disease (CHD). Alternative treatment strategies, such as ezetimibe coadministration and s
Autor:
Ramachandran Suresh, Philip T. Sager, Leslie Lipka, Lorenzo Melani, Enrico P. Veltri, Susan Bennett
Publikováno v:
Journal of women's health (2002). 13(10)
Women are often not treated as aggressively as men to control levels of low-density lipoprotein cholesterol (LDL-C), despite evidence that women and men realize comparable cardiovascular benefit from lipid-lowering therapy. Statins are the most effec
Autor:
Enrico P. Veltri, Damien Ponsonnet, Steen Stender, Evan A. Stein, Leslie Lipka, Darbie Maccubbin, Pedro Mata, Ramachandran Suresh, Lorenzo Melani, Philip T. Sager
Publikováno v:
American heart journal. 148(3)
Despite the efficacy of statins in lowering low-density lipoprotein cholesterol (LDL-C) levels, many patients who are at high risk for heart disease with hypercholesterolemia require additional LDL-C level reduction. The cholesterol absorption inhibi