Zobrazeno 1 - 10 of 22 pro vyhledávání: '"Leslie L. Leinwand"'
1
Effects of spaceflight on murine skeletal muscle gene expression
Autor: Brooke C. Harrison, W. Scott Argraves, Jeremy L. Barth, Paul J. Kostenuik, Leslie L. Leinwand, David L. Allen, Sean Morony, Ted A. Bateman, Timothy G. Hammond, Seiha Thorng, David L. Lacey, Louis S. Stodieck, Eric R. Bandstra
Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985). 106(2)
Spaceflight results in a number of adaptations to skeletal muscle, including atrophy and shifts toward faster muscle fiber types. To identify changes in gene expression that may underlie these adaptations, we used both microarray expression analysis
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ad533d8628d7e852e870dc83905b58
https://pubmed.ncbi.nlm.nih.gov/19074574
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3
Use of integrin-linked kinase to extend function of encapsulated pancreatic tissue
Autor: Steven J Langer, Kristi S. Anseth, Pritesh S Topiwala, Suchit Sahai, Leslie L. Leinwand, James O. Blanchette
Publikováno v: Biomedical Materials. 5:061001
We have studied the impact of overexpression of an intracellular signaling protein, integrin-linked kinase (ILK), on the survival and function of encapsulated islet tissue used for the treatment of type 1 diabetes. The dimensions of the encapsulated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2677e46af3849a796e2717d2efec6cc6
https://doi.org/10.1088/1748-6041/5/6/061001
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4
Akademický článek
Cardiac splicing as a diagnostic and therapeutic target.
Autor: Gotthardt M; Neuromuscular and Cardiovascular Cell Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany. gotthardt@mdc-berlin.de.; DZHK (German Center for Cardiovascular Research Partner Site Berlin), Berlin, Germany. gotthardt@mdc-berlin.de.; Department of Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany. gotthardt@mdc-berlin.de., Badillo-Lisakowski V; Neuromuscular and Cardiovascular Cell Biology, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany.; DZHK (German Center for Cardiovascular Research Partner Site Berlin), Berlin, Germany., Parikh VN; Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, Palo Alto, CA, USA., Ashley E; Stanford Center for Inherited Cardiovascular Disease, Stanford University School of Medicine, Palo Alto, CA, USA.; Stanford Genome Technology Center, Stanford University, Palo Alto, CA, USA.; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA., Furtado M; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Carmo-Fonseca M; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal., Schudy S; Institute for Cardiomyopathies, Department of Medicine III, University of Heidelberg, Heidelberg, Germany., Meder B; Institute for Cardiomyopathies, Department of Medicine III, University of Heidelberg, Heidelberg, Germany.; DZHK (German Center for Cardiovascular Research Partner Site Heidelberg-Mannheim), Heidelberg, Germany., Grosch M; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany., Steinmetz L; Stanford Genome Technology Center, Stanford University, Palo Alto, CA, USA.; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, USA.; European Molecular Biology Laboratory (EMBL), Genome Biology Unit, Heidelberg, Germany., Crocini C; Department of Molecular, Cellular, and Developmental Biology and BioFrontiers Institute, University of Colorado, Boulder, CO, USA., Leinwand L; Department of Molecular, Cellular, and Developmental Biology and BioFrontiers Institute, University of Colorado, Boulder, CO, USA.
Publikováno v: Nature reviews. Cardiology [Nat Rev Cardiol] 2023 Aug; Vol. 20 (8), pp. 517-530. Date of Electronic Publication: 2023 Jan 18.
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5
Divergent Molecular Phenotypes in Point Mutations at the Same Residue in Beta-Myosin Heavy Chain Lead to Distinct Cardiomyopathies.
Autor: Lehman SJ; University of Colorado, Molecular, Cellular, and Developmental Biology, Boulder, CO, USA., Meller A; Washington University in St. Louis, Department of Biochemistry and Molecular Biophysics, St. Louis, MO, USA.; Medical Scientist Training Program, Washington University in St. Louis, St. Louis, MO, USA., Solieva SO; University of Pennsylvania, Department of Biochemistry and Biophysics, Philadelphia, PA, USA., Lotthammer JM; Washington University in St. Louis, Department of Biochemistry and Molecular Biophysics, St. Louis, MO, USA., Greenberg L; Washington University in St. Louis, Department of Biochemistry and Molecular Biophysics, St. Louis, MO, USA., Langer SJ; University of Colorado, Molecular, Cellular, and Developmental Biology, Boulder, CO, USA., Greenberg MJ; Washington University in St. Louis, Department of Biochemistry and Molecular Biophysics, St. Louis, MO, USA., Tardiff JC; University of Arizona, Department of Biomedical Engineering, Tucson, AZ, USA., Bowman GR; University of Pennsylvania, Department of Biochemistry and Biophysics, Philadelphia, PA, USA., Leinwand L; University of Colorado, Molecular, Cellular, and Developmental Biology, Boulder, CO, USA.
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Jul 03. Date of Electronic Publication: 2023 Jul 03.
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6
Akademický článek
Just 2% of SARS-CoV-2-positive individuals carry 90% of the virus circulating in communities.
Autor: Yang Q; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80303., Saldi TK; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Gonzales PK; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Lasda E; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Decker CJ; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80303.; HHMI, University of Colorado Boulder, Boulder, CO 80303., Tat KL; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Fink MR; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Hager CR; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Davis JC; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Ozeroff CD; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Muhlrad D; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80303.; HHMI, University of Colorado Boulder, Boulder, CO 80303., Clark SK; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Darwin Biosciences Inc., Boulder, CO 80303., Fattor WT; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Meyerson NR; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Darwin Biosciences Inc., Boulder, CO 80303., Paige CL; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Darwin Biosciences Inc., Boulder, CO 80303., Gilchrist AR; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80303., Barbachano-Guerrero A; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303., Worden-Sapper ER; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80303., Wu SS; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80303.; Interdisciplinary Quantitative Biology Program, University of Colorado Boulder, Boulder, CO 80303., Brisson GR; Wardenburg Health Center, University of Colorado Boulder, Boulder, CO 80303., McQueen MB; Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO 80303., Dowell RD; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80303.; Department of Computer Science, University of Colorado Boulder, Boulder, CO 80303., Leinwand L; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80303., Parker R; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303; Roy.Parker@Colorado.EDU ssawyer@colorado.EDU.; Department of Biochemistry, University of Colorado Boulder, Boulder, CO 80303.; HHMI, University of Colorado Boulder, Boulder, CO 80303., Sawyer SL; BioFrontiers Institute, University of Colorado Boulder, Boulder, CO 80303; Roy.Parker@Colorado.EDU ssawyer@colorado.EDU.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO 80303.
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 May 25; Vol. 118 (21).
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7
Saliva TwoStep for rapid detection of asymptomatic SARS-CoV-2 carriers.
Autor: Yang Q; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, 80303., Meyerson NR; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Darwin Biosciences Inc., Boulder, Colorado, 80303, USA., Clark SK; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Darwin Biosciences Inc., Boulder, Colorado, 80303, USA., Paige CL; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Fattor WT; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Gilchrist AR; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, 80303., Barbachano-Guerrero A; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Healy BG; Department of Mechanical Engineering, University of Colorado Boulder, Boulder, Colorado, 80303., Worden-Sapper ER; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, 80303., Wu SS; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, 80303.; Interdisciplinary Quantitative Biology Graduate Program, University of Colorado Boulder, Boulder, Colorado, 80303., Muhlrad D; Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado, 80303.; Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Decker CJ; Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado, 80303.; Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Saldi TK; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Lasda E; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Gonzales PK; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, 80303., Fink MR; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Tat KL; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Hager CR; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Davis JC; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, 80303., Ozeroff CD; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Brisson GR; Wardenburg Health Center, University of Colorado Boulder, Boulder, Colorado, 80303., McQueen MB; Department of Integrative Physiology, University of Colorado Boulder, Boulder, Colorado, 80303., Leinwand L; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, 80303., Parker R; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado, 80303.; Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, Colorado, 80303., Sawyer SL; BioFrontiers Institute, University of Colorado Boulder, Boulder, Colorado, 80303.; Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, 80303.
Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2021 Feb 16. Date of Electronic Publication: 2021 Feb 16.
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8
Akademický článek
Computational Approach to Measuring Myocyte Disarray in Animal Models of Heart Disease.
Autor: Wan W; Biofrontiers Institute, University of Colorado at Boulder, Boulder, Colorado., Leinwand L; Biofrontiers Institute, University of Colorado at Boulder, Boulder, Colorado.
Publikováno v: Current protocols in human genetics [Curr Protoc Hum Genet] 2017 Apr 06; Vol. 93, pp. 15.11.1-15.11.9. Date of Electronic Publication: 2017 Apr 06.
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9
Akademický článek
The Most Prevalent Freeman-Sheldon Syndrome Mutations in the Embryonic Myosin Motor Share Functional Defects.
Autor: Walklate J; From the School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom and., Vera C; the Department of Molecular and Developmental Biology, University of Colorado, Boulder, Colorado 80309., Bloemink MJ; From the School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom and., Geeves MA; From the School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom and M.A.Geeves@kent.ac.uk., Leinwand L; the Department of Molecular and Developmental Biology, University of Colorado, Boulder, Colorado 80309 leslie.leinwand@Colorado.edu.
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2016 May 06; Vol. 291 (19), pp. 10318-31. Date of Electronic Publication: 2016 Mar 04.
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10
Akademický článek
The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosin.
Autor: Bloemink M; From the School of Biosciences, University of Kent, Canterbury CT2 7NJ, United Kingdom and., Deacon J, Langer S, Vera C, Combs A, Leinwand L, Geeves MA
Publikováno v: The Journal of biological chemistry [J Biol Chem] 2014 Feb 21; Vol. 289 (8), pp. 5158-67. Date of Electronic Publication: 2013 Dec 16.
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