Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Leslie L. Glass"'
Autor:
Leslie L. Glass, Fernando J. Calero-Nieto, Wajid Jawaid, Pierre Larraufie, Richard G. Kay, Berthold Göttgens, Frank Reimann, Fiona M. Gribble
Publikováno v:
Molecular Metabolism, Vol 6, Iss 10, Pp 1296-1303 (2017)
Objectives: To identify sub-populations of intestinal preproglucagon-expressing (PPG) cells producing Glucagon-like Peptide-1, and their associated expression profiles of sensory receptors, thereby enabling the discovery of therapeutic strategies tha
Externí odkaz:
https://doaj.org/article/ff21e3a15a5446839e4a4375369c7fc0
Autor:
Fiona M. Gribble, Geoffrey P. Roberts, Marcella Ma, Brian Y.H. Lam, Raphael Scharfmann, Davide Chiarugi, Pierre Larraufie, Richard H. Hardwick, Richard G. Kay, Frank Reimann, Leslie L Glass, Paul Richards, Joyce Li, Giles S.H. Yeo, Emily L. Miedzybrodzka, Sam G Galvin, Andrew B. Leiter
Publikováno v:
Diabetes
Diabetes, American Diabetes Association, 2019, 68 (5), pp.1062-1072. ⟨10.2337/db18-0883⟩
Diabetes, American Diabetes Association, 2019, 68 (5), pp.1062-1072. ⟨10.2337/db18-0883⟩
Enteroendocrine cells (EECs) produce hormones such as glucagon-like peptide 1 and peptide YY that regulate food absorption, insulin secretion, and appetite. Based on the success of glucagon-like peptide 1–based therapies for type 2 diabetes and obe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d103696f7fdfe7b30fe6f21bc38b4f
Autor:
Fiona M. Gribble, Eleftheria Diakogiannaki, Leslie L Glass, Catherine E. Moss, Carol Lenaghan, Marianne Wedin, Mohammad Bohlooly-Y, David M. Smith, Ramona Pais, Frank Reimann
Publikováno v:
Peptides
Highlights • GPR119, a putative fat sensor, is a potential target for metabolic disease. • KO of GPR119 in murine L-cells reduced GLP-1 response to fat in vivo. • Primary L-cells secreted GLP-1 in response to GPR119 agonists. • GPR119 agonist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed2db20a6d3b53ae9ed4b408432d27c5
Autor:
Rune E. Kuhre, Fiona M. Gribble, Frank Reimann, Juraj Rievaj, Leslie L Glass, Cheryl A. Brighton, Jens J. Holst
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::478623dc65a45c59e4ce87613859a69a
https://doi.org/10.1530/endoabs.38.p208
https://doi.org/10.1530/endoabs.38.p208
Publikováno v:
British Journal of Pharmacology
Background and Purpose Galanin is a widely expressed neuropeptide, which in the gut is thought to modulate gastrointestinal motility and secretion. We aimed to elucidate the poorly characterised mechanisms underlying the inhibitory effect of galanin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e5a7aff5445af2d4a0b21c4487e7426f
https://pubmed.ncbi.nlm.nih.gov/26661062
https://pubmed.ncbi.nlm.nih.gov/26661062
Autor:
Billing LJ; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Smith CA; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Larraufie P; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Goldspink DA; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Galvin S; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Kay RG; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Howe JD; MRC-Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK., Walker R; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Pruna M; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Glass L; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Pais R; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK., Gribble FM; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK. Electronic address: fmg23@cam.ac.uk., Reimann F; Institute of Metabolic Sciences and MRC-Metabolic Diseases Unit, University of Cambridge, Cambridge, CB0 0QQ, UK. Electronic address: fr222@cam.ac.uk.
Publikováno v:
Molecular metabolism [Mol Metab] 2018 Oct; Vol. 16, pp. 65-75. Date of Electronic Publication: 2018 Jul 30.
Autor:
Coyne JH; Kessler Foundation, West Orange, NJ; Children's Specialized Hospital, Mountainside, NJ; Department of Physical Medicine and Rehabilitation, New Jersey Medical School, Rutgers University, Newark, NJ., Borg JM; Children's Specialized Hospital, Mountainside, NJ., DeLuca J; Kessler Foundation, West Orange, NJ; Department of Physical Medicine and Rehabilitation, New Jersey Medical School, Rutgers University, Newark, NJ; Department of Neurology and Neurosciences, New Jersey Medical School, Rutgers University, Newark, NJ., Glass L; Children's Specialized Hospital, Mountainside, NJ., Sumowski JF; Kessler Foundation, West Orange, NJ; Children's Specialized Hospital, Mountainside, NJ; Department of Physical Medicine and Rehabilitation, New Jersey Medical School, Rutgers University, Newark, NJ. Electronic address: jsumowski@kesslerfoundation.org.
Publikováno v:
Archives of physical medicine and rehabilitation [Arch Phys Med Rehabil] 2015 Apr; Vol. 96 (4), pp. 742-5. Date of Electronic Publication: 2014 Oct 13.