Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Leslie J. Marden"'
Autor:
Joseph M. Lane, Leslie J. Marden, C. Michael Philbrook, Eyal S. Ron, Thomas J. Turek, Mathias P.G. Bostrom, Lisa Jin, Jeffrey O. Hollinger, Richard A. Kenley, Jennifer L. Smith, Thomas Parsons, Emre Tomin
Publikováno v:
Journal of Controlled Release. 36:183-195
Novel delivery systems for the bone morphogenetic protein rhBMP-2, consisting of poly( d,l -lactide-co-glycolide) porous microspheres as bioabsorbable filling material with either autologous blood clot or carboxymethylcellulose as binding agent, were
Publikováno v:
Calcified Tissue International. 53:262-268
Repair of rat craniotomy defects, 8 mm in diameter, was compared with that of defects treated with either rat insoluble collagenous bone matrix (ICBM) or partially purified bovine osteogenin, a bone-inductive protein, reconstituted with ICBM (OG/ICBM
Autor:
Jeffrey O. Hollinger, Eyal S. Ron, Leslie J. Marden, Joan Abrams, Richard A. Kenley, Kalvin W. K. Yim, Tom Turek
Publikováno v:
Pharmaceutical Research. 10:1393-1401
Trauma, disease, developmental deformities, and tumor resection frequently cause bone defects that seriously challenge the skills of orthopedic and maxillofacial surgeons. Currently, repairing osseous deficiencies involves various medical surgical te
Autor:
A. H. Reddi, Charles Hastings, George Chen, Leslie J. Marden, Deiren E Mark, Jeffrey O. Hollinger
Publikováno v:
Plastic and Reconstructive Surgery. 86:623-630
Efforts were taken to determine the dose of bovine osteogenin (OG) that would induce more bone than that induced by 20 mg of rat particulate demineralized bone matrix (DBM), the amount allowed by the confines of an 8-mm rat craniotomy defect. Dose-re
Publikováno v:
Journal of Craniofacial Surgery. 1:154-161
Repair of craniofacial bone often requires autogenous or allogeneic bone. Natural materials deliver bone-inducing substances to wound beds and provide scaffolding for osteoconduction, but not without risk of morbidity. We are developing a synthetic m
Autor:
Anshumali Chaudhari, Tom Turek, Robert G. Schaub, Eyal S. Ron, Leslie J. Marden, Jeffrey O. Hollinger
Publikováno v:
Journal of biomedical materials research. 28(10)
The purpose of this study was to measure bone-regenerative effects of recombinant human bone morphogenetic protein-2 (rhBMP-2) in rat calvarial critical-size defects (CSDs). CSDs (8 mm in diameter) were treated with either 1) 2.2 micrograms rhBMP-2 c
Publikováno v:
The Journal of craniofacial surgery. 1(3)
In an effort to minimize problems associated with use of bone grafts and bank bone for craniofacial reconstruction, synthetic biodegradable alternatives are under development at the U.S. Army Institute of Dental Research. The focus is on composite ma