Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Leslie D. McLaughlin"'
Autor:
C. Brad eWilson, Leslie D. McLaughlin, Philip J. Ebenezer, Anand R. Nair, Rahul eDange, Joseph G. Harre, Thomas L. Shaak, David M Diamond, Joseph eFrancis
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Serotonin (5-HT), norepinephrine (NE), and other neurotransmitters are modulated in post-traumatic stress disorder (PTSD). In addition, pro-inflammatory cytokines (PIC) are elevated during the progression of the disorder. Currently, the only approved
Externí odkaz:
https://doaj.org/article/e376218b1769412babfd4f1dbbc18c29
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89104 (2014)
Post-Traumatic Stress Disorder (PTSD) can develop in response to a traumatic event involving a threat to life. To date, no diagnostic biomarkers have been identified for PTSD. Recent research points toward physiological abnormalities in the hypothala
Externí odkaz:
https://doaj.org/article/1547552db1d44f37a59a05a8c62e2c24
Autor:
C Brad Wilson, Leslie D McLaughlin, Anand Nair, Philip J Ebenezer, Rahul Dange, Joseph Francis
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e76146 (2013)
This study sought to analyze specific pathophysiological mechanisms involved in the progression of post-traumatic stress disorder (PTSD) by utilizing an animal model. To examine PTSD pathophysiology, we measured damaging reactive oxygen species and i
Externí odkaz:
https://doaj.org/article/69214167c2f541769a12abc6a0750cbf
Autor:
Konstantin G. Kousoulas, Seetharama D. Jois, Leslie D. McLaughlin, Rushikesh Sable, Jason D. Walker, Ameya Gokhale
Publikováno v:
Biopolymers. 104:733-742
CD2 and CD58 are two important costimulatory molecules involved in generating the signal II required for normal immune signaling. However, this interaction can be targeted to be of benefit in cases of abnormal immune signaling seen in autoimmune dise
Publikováno v:
Behavioural Brain Research. 268:72-80
Reactive oxygen species (ROS) and pro-inflammatory cytokines (PIC) are upregulated in post-traumatic stress disorder (PTSD). Histone deacetylase inhibitors (HDACi) modify genetic transcription and can diminish ROS and PIC escalation. They can also mo
Autor:
Krista A. Keller, João Brandão, Leslie D. McLaughlin, Hugues Beaufrère, Rudy W. Bauer, Thomas N. Tully
Publikováno v:
Journal of Avian Medicine and Surgery. 27:44-52
Cockatiels (Nymphicus hollandicus) are commonly diagnosed with ovarian neoplasia. However, there is very little information regarding medical management of this disease condition and subsequent patient response. Long-term medical therapy of 2 cockati
Publikováno v:
Military medicine. 181(11)
Recent conflicts have contributed to an escalation in combat-related psychiatric disorders, including post-traumatic stress disorder (PTSD). Although technological advances have increased the speed from which battlefield injuries reach definitive car
Autor:
Thomas N. Tully, Gwendolyn Jankowski, Hugues Beaufrère, Leslie D. McLaughlin, Nobuko Wakamatsu, Manoj Bhaskaran
Publikováno v:
Journal of Avian Medicine and Surgery. 23:325-328
Autor:
Daniel J. DiLorenzo, Leslie D. McLaughlin, Andrew T. Roberts, Frank L. Greenway, Jolene Zheng
Publikováno v:
Medical Hypotheses. 72:706-710
Summary Sympathetic activity and obesity have a reciprocal relationship. Firstly, hypothalamic obesity is associated with decreased sympathetic activity. Caffeine and ephedrine increase sympathetic activity and induce weight loss, of which 25% is due
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 666:16-22
Human ribosomal protein S3 (RPS3) has previously been shown to have alternative roles beyond its participation in protein synthesis. For example, our in vitro studies have shown that RPS3 has an extraordinarily high binding affinity for 7, 8-dihydro-