Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Leslie C. Sutherland"'
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 1568-1572 (2018)
Presented herein are RNA expression data linked to the exposure of human lung epithelial cells to either low dose radon-emitting rock, tobacco smoke or cannabis smoke. Two cell lines were used, one representing a ‘normal’ lung epithelial cell (BE
Externí odkaz:
https://doaj.org/article/67e912be593d4fdcbad8e46431d5ec01
Publikováno v:
Heliyon, Vol 2, Iss 11 (2016)
Small cell lung cancer (SCLC) is the most aggressive type of lung cancer, with almost 95% of patients succumbing to the disease. Although RBM5, a tumor suppressor gene, is downregulated in the majority of lung cancers, its role in SCLC is unknown. Us
Externí odkaz:
https://doaj.org/article/919ed0ce912f4e699f0f7f4caf73aa67
Regulation of T-Cell Apoptosis by Sequences Encoded at the Luca-15 Candidate Tumour Suppressor Locus
Autor:
Mirna Mourtada-Maarabouni, Leslie C. Sutherland, Jeremy P. Clark, Colin S. Cooper, Gwyn T. Williams
Publikováno v:
The Scientific World Journal, Vol 1, Pp 38-38 (2001)
Externí odkaz:
https://doaj.org/article/78f3448339ed4f76966e3631407066a3
Publikováno v:
Journal of Environmental Radioactivity. 196:64-81
Radon is the second leading cause of lung cancer, after tobacco smoke. While tobacco smoke-induced carcinogenesis has been studied extensively, far less is known about radon-induced carcinogenesis, particularly in relation to the influence of radon o
Autor:
Justin G. Roy, Jose M. Knee, Benoit Chabot, Roscoe Klinck, Gustavo Ybazeta, Philippe Thibault, Lincoln Stein, Sarah C. Hunt, Mathieu Durand, Ariane Beauvais, Elvy Lapointe, Julie J. Loiselle, Sarah J. Tessier, Irina Kalatskaya, Rashmi Kothary, Leslie C. Sutherland
Publikováno v:
BMC Molecular Biology, Vol 18, Iss 1, Pp 1-14 (2017)
BMC Molecular Biology
BMC Molecular Biology
Background RBM10 is an RNA binding protein involved in message stabilization and alternative splicing regulation. The objective of the research described herein was to identify novel targets of RBM10-regulated splicing. To accomplish this, we downreg
Autor:
Leslie C. Sutherland, Julie J. Loiselle, Kaitlin A. Vanderbeck, Benjamin W Koenderink, Twinkle J. Masilamani, Bartholomew Ozuemba, Jose M. Knee, Céline Larivière
Publikováno v:
Gene. 580:26-36
Background Expression and function of the two RNA binding proteins and regulators of alternative splicing, RBM5 and RBM10, have largely been studied in human tissue and cell lines. The objective of the study described herein was to examine their expr
Publikováno v:
In Vitro Cellular & Developmental Biology. Animal
We previously examined the expression of Rbm5 during myoblast differentiation and found significantly more protein in the early stages of skeletal myoblast differentiation than during the later stages. We decided to determine if this elevated level w
Publikováno v:
Data in Brief
Data in Brief, Vol 21, Iss, Pp 1568-1572 (2018)
Data in Brief, Vol 21, Iss, Pp 1568-1572 (2018)
Presented herein are RNA expression data linked to the exposure of human lung epithelial cells to either low dose radon-emitting rock, tobacco smoke or cannabis smoke. Two cell lines were used, one representing a ‘normal’ lung epithelial cell (BE
Publikováno v:
Journal of Cellular Biochemistry
RBM10 is an RNA binding motif (RBM) protein expressed in most, if not all, human and animal cells. Interest in RBM10 is rapidly increasing and its clinical importance is highlighted by its identification as the causative agent of TARP syndrome, a dev
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 6, p e0180258 (2017)
PLoS ONE, Vol 12, Iss 6, p e0180258 (2017)
Lung cancers are the leading cause of cancer-related deaths worldwide, with small cell lung cancer (SCLC) being the most aggressive type. At the time of diagnosis, SCLC has usually already metastasized, and an astonishing 95% of patients eventually s