Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Leslie C. Osborne"'
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Efficient coding suggests that adapting gain to match the varying stimulus statistics should help in optimizing behaviour. Here the authors show that adaptation in motion sensitive neurons maximizes information and improves movement accuracy in pursu
Externí odkaz:
https://doaj.org/article/9bac2477ce524487a75388dcf91b324b
Autor:
Haiyan eLi, Sarah M. Foss, Yuriy eDobryy, C. Kevin ePark, Samuel Andrew Hires, Nathan C. Shaner, Roger Y. Tsien, Leslie C. Osborne, Susan M. Voglmaier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 4 (2011)
Synaptic transmission involves the calcium-dependent release of neurotransmitter from synaptic vesicles. Genetically encoded optical probes emitting different wavelengths of fluorescent light in response to neuronal activity offer a powerful approach
Externí odkaz:
https://doaj.org/article/bd3772baf3d74e6d8bd509f02b7efa05
Many sensory neurons encode information about more than one stimulus feature. Multidimensional tuning increases ambiguity in stimulus-response relationships, but we find that it also offers an unexpected computational advantage, allowing the brain to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9db379e9ead9030e159f11c9288d5766
https://doi.org/10.1101/2020.12.29.424235
https://doi.org/10.1101/2020.12.29.424235
Spatiotemporal Filter for Visual Motion Integration from Pursuit Eye Movements in Humans and Monkeys
Publikováno v:
The Journal of Neuroscience. 37:1394-1412
Despite the enduring interest in motion integration, a direct measure of the space–time filter that the brain imposes on a visual scene has been elusive. This is perhaps because of the challenge of estimating a 3D function from perceptual reports i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041f7f8aa5509a1bf8b26e5d662a731c
https://doi.org/10.1523/jneurosci.2682-16.2016
https://doi.org/10.1523/jneurosci.2682-16.2016
Autor:
Marc W. Slutzky, Suchin Gururangan, Mukta Vaidya, Karim Oweiss, Ahmed Eleryan, Andrew H. Fagg, Leslie C. Osborne, Kelsey Shattuck, Joshua Southerland, Islam Badreldin, Karthikeyan Balasubramanian, Nicholas G. Hatsopoulos
Publikováno v:
Journal of neurophysiology. 119(4)
The development of coordinated reach-to-grasp movement has been well studied in infants and children. However, the role of motor cortex during this development is unclear because it is difficult to study in humans. We took the approach of using a bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::246dc8d7eeebd9c8ce076631f5084947
https://pubmed.ncbi.nlm.nih.gov/29924714
https://pubmed.ncbi.nlm.nih.gov/29924714
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 10, p e1006527 (2018)
PLoS Computational Biology
PLoS Computational Biology
Behavioral states marked by varying levels of arousal and attention modulate some properties of cortical responses (e.g. average firing rates or pairwise correlations), yet it is not fully understood what drives these response changes and how they mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1697fddc4ed97af6ac97adf87cfb780e
Publikováno v:
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
In the natural world, the statistics of sensory stimuli fluctuate across a wide range. In theory, the brain could maximize information recovery if sensory neurons adaptively rescale their sensitivity to the current range of inputs. Such adaptive codi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e09922f5a2e9c7686f7314d98461e03e
http://europepmc.org/articles/PMC5023965
http://europepmc.org/articles/PMC5023965
Autor:
Leslie C. Osborne
Publikováno v:
Current Opinion in Neurobiology. 21:623-628
Performance in sensory-motor behaviors guides our understanding of many of the key computational functions of the brain: the representation of sensory information, the translation of sensory signals to commands for movement, and the production of beh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc65bfbc7fc93ee7a22074d9b1da756
https://doi.org/10.1016/j.conb.2011.05.023
https://doi.org/10.1016/j.conb.2011.05.023
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(22)
Are sensory estimates formed centrally in the brain and then shared between perceptual and motor pathways or is centrally represented sensory activity decoded independently to drive awareness and action? Questions about the brain's information flow p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af67b4f06ac1dd8e117839a31ba3625f
https://pubmed.ncbi.nlm.nih.gov/26041919
https://pubmed.ncbi.nlm.nih.gov/26041919
Publikováno v:
Nature. 437:412-416
Suppose that the variability in our movements1–9 is caused not by noise in the motor system itself, nor by fluctuations in our intentions or plans, but rather by errors in our sensory estimates of the external parameters that define the appropriate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7527e27787d28f8ff66fb1ff54d16e1
https://doi.org/10.1038/nature03961
https://doi.org/10.1038/nature03961