Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Leslie C Newman"'
Autor:
Audrey C Papp, Julia K Pinsonneault, Danxin Wang, Leslie C Newman, Yan Gong, Julie A Johnson, Carl J Pepine, Meena Kumari, Aroon D Hingorani, Philippa J Talmud, Sonia Shah, Steve E Humphries, Wolfgang Sadee
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e31930 (2012)
Polymorphisms in and around the Cholesteryl Ester Transfer Protein (CETP) gene have been associated with HDL levels, risk for coronary artery disease (CAD), and response to therapy. The mechanism of action of these polymorphisms has yet to be defined
Externí odkaz:
https://doaj.org/article/e6846031eab348b5a7925fc31e4fa446
Autor:
Wolfgang Sadee, Audrey C. Papp, Thomas Toneff, Leslie C. Newman, Katherine Hartmann, Adam Suhy, Vivian Hook
Publikováno v:
Biochemical and Biophysical Research Communications. 443:1270-1274
Cholesteryl ester transfer protein (CETP) plays an important role in reverse cholesterol transport, with decreased CETP activity increasing HDL levels. Formation of an alternative splice form lacking exon 9 (Δ9-CETP) has been associated with two sin
Autor:
Leslie C. Newman, Taryn Summerfield, Erica Hlavin Bell, John T. Tansey, Zach Niday, Brian Patterson, Sadie R. Bartholomew, William E. Ackerman, Erin L. Miller
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1821:268-278
The PAT family of lipid storage droplet proteins comprised five members, each of which has become an established regulator of cellular neutral lipid metabolism. Perilipin 5 (also known as lsdp-5, MLDP, PAT-1, and OXPAT), the most recently discovered
Autor:
Wolfgang Sadee, Maciej Pietrzak, Amanda Curtis, Caryn Lerman, Audrey C. Papp, Grzegorz A. Rempala, John R. Kelsoe, Deborah C. Mash, Rachel F. Tyndale, Michal Seweryn, Daqing Wang, Erica Graziosa, Leslie C. Newman, Samuel K. Handelman, Amy Webb
Publikováno v:
BMC Genomics
BMC genomics, vol 16, iss 1
BMC genomics, vol 16, iss 1
Background We used RNA sequencing to analyze transcript profiles of ten autopsy brain regions from ten subjects. RNA sequencing techniques were designed to detect both coding and non-coding RNA, splice isoform composition, and allelic expression. Bra
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 41:43-48
Initial studies were undertaken to examine the properties of [3H]-diprenorphine binding to Rana pipiens whole brain tissue using naltrexone for the definition of nonspecific binding. Saturation analysis demonstrated the binding of [3H]-diprenorphine
Autor:
Julia K. Pinsonneault, Leslie C. Newman, Audrey C. Papp, Aroon D. Hingorani, Philippa J. Talmud, Steve E. Humphries, Yan Gong, Carl J. Pepine, Wolfgang Sadee, Danxin Wang, Sonia Shah, Meena Kumari, Julie A. Johnson
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 3, p e31930 (2012)
PLoS ONE, Vol 7, Iss 3, p e31930 (2012)
Polymorphisms in and around the Cholesteryl Ester Transfer Protein (CETP) gene have been associated with HDL levels, risk for coronary artery disease (CAD), and response to therapy. The mechanism of action of these polymorphisms has yet to be defined
Publikováno v:
European journal of pharmacology. 397(2-3)
Opioid receptor ligands have been shown to elicit antinociception in mammals through three distinct types of receptors designated as mu, delta and kappa. These opioid receptors have been characterized and cloned in several mammalian species. Radiolig
Autor:
Leslie C. Newman, Craig W. Stevens
Publikováno v:
Life sciences. 64(10)
In mammals, opioids act by interactions with three distinct types of receptors: mu, delta, or kappa opioid receptors. Using a novel assay of antinociception in the Northern grass frog, Rana pipiens, previous work demonstrated that selective mu, delta
Autor:
Adam Suhy, Wolfgang Sadee, Amy Webb, John Oberdick, Roshan Mascarenhas, Samuel K. Handelman, Ryan M. Smith, Leslie C. Newman, Audrey C. Papp
Publikováno v:
BMC Genomics
Background Measuring allelic RNA expression ratios is a powerful approach for detecting cis-acting regulatory variants, RNA editing, loss of heterozygosity in cancer, copy number variation, and allele-specific epigenetic gene silencing. Whole transcr