Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Leslie Burke"'
Publikováno v:
Clinical Interventions in Aging, Vol Volume 4, Pp 31-50 (2008)
Mark A Babizhayev1, Leslie Burke2, Philip Micans3, Stuart P Richer4,51Innovative Vision Products, Inc., County of New Castle, Delaware, USA; 2Wise Choice Products LLC, London, England, United Kingdom; 3IAS Group, Sark, United Kingdom; 4Eye Clinic DVA
Externí odkaz:
https://doaj.org/article/6efa6d7812914e16a005c86b5b78bb27
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e68103 (2013)
Bone metastases are severely debilitating and have a significant impact on the quality of life of women with metastatic breast cancer. Treatment options are limited and in order to develop more targeted therapies, improved understanding of the comple
Externí odkaz:
https://doaj.org/article/d729da9d31a340a7a47666a520fdc9d6
Autor:
Darrell H. G. Crawford, Xin Liu, Xiaowen Liang, Xinxing Li, Jatin Patel, Wenchao Gao, Victoria C. Cogger, Kim R. Bridle, Michael S. Roberts, Brian W.C. Tse, Haolu Wang, Leslie Burke, Haotian Yang
Publikováno v:
Theranostics
Acetaminophen (APAP) is the foremost cause of drug-induced liver injury in the Western world. Most studies of APAP hepatotoxicity have focused on the hepatocellular injury, but current hepatocyte-related biomarkers have delayed presentation time and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f0824a8d4659af6ed98d86b2d0ce22
https://pubmed.ncbi.nlm.nih.gov/32550899
https://pubmed.ncbi.nlm.nih.gov/32550899
Autor:
Lesley Jaskowski, Nick Musgrave, Diana G. F. Ross, Kim R. Bridle, Gautam Rishi, Leslie Burke, Laurence J. Britton, Darrell H. G. Crawford, David Briskey, V. Nathan Subramaniam
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1867:166142
Background & aims Iron has been proposed as influencing the progression of liver disease in subjects with non-alcoholic fatty liver disease (NAFLD). We have previously shown that, in the Hfe−/− mouse model of hemochromatosis, feeding of a high-ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63ee1077bc1da7a986ab0e3a61b65107
https://doi.org/10.1016/j.bbadis.2021.166142
https://doi.org/10.1016/j.bbadis.2021.166142
Autor:
Arjen R. Mensenkamp, Paolo Radice, Mark E. Robson, Emma Tudini, Amanda B. Spurdle, Susan M. Domchek, Melissa A. Brown, Logan C. Walker, Miguel de la Hoya, Sean V. Tavtigian, Diana Eccles, Leslie Burke, Thilo Dörk, Clare Turnbull, Antonis C. Antoniou, Michael T. Parsons, Stephanie Greville-Heygate, Maaike P.G. Vreeswijk, Marc Tischkowitz, Alvaro N.A. Monteiro, Helen V. Firth
Publikováno v:
Journal of Medical Genetics, 56, 6, pp. 347-357
Journal of Medical Genetics, 56, 347-357
Journal of Medical Genetics, 56(6), 347-357. BMJ PUBLISHING GROUP
Journal of Medical Genetics
Journal of Medical Genetics, 56, 347-357
Journal of Medical Genetics, 56(6), 347-357. BMJ PUBLISHING GROUP
Journal of Medical Genetics
The vocabulary currently used to describe genetic variants and their consequences reflects many years of studying and discovering monogenic disease with high penetrance. With the recent rapid expansion of genetic testing brought about by wide availab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67312ed4dc823e52d80c5308bf50e7e
https://hdl.handle.net/2066/205066
https://hdl.handle.net/2066/205066
Autor:
Eliseos J. Mucaki, Stacey L. Edwards, Marinus J. Blok, Jana Soukupova, Mariana Borecka, Marta Santamariña, Marketa Janatova, Paolo Peterlongo, Ana Vega, Ben C. Shirley, Amanda B. Spurdle, Peter K. Rogan, Gaetana Gambino, Phillip J. Whiley, Lenka Stolarova, Petra Zemankova, O. Diez, Siranoush Manoukian, Thomas van Overeem Hansen, David E. Goldgar, Bernardo Bonanni, Emma Tudini, Sara Gutiérrez-Enríquez, Leslie Burke, Elizabeth Santana dos Santos, Michael T. Parsons, Kathleen Claes, Jan Sevcik, Kim De Leeneer, Melissa A. Brown, Paolo Radice, Maria Caligo, Etienne Rouleau, Sandrine M. Caputo, Alejandro Moles-Fernández, Maria Rossing, Klara Lhotova
Publikováno v:
Biochemistry Publications
HUMAN MUTATION
Human Mutation, 39(12), 2025-2039. Wiley
Human Mutation
HUMAN MUTATION
Human Mutation, 39(12), 2025-2039. Wiley
Human Mutation
© 2018 The Authors. Human Mutation published by Wiley Periodicals, Inc. The widespread use of next generation sequencing for clinical testing is detecting an escalating number of variants in noncoding regions of the genome. The clinical significance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29835828575937de15cde6b0b4f3a90d
https://ir.lib.uwo.ca/biochempub/218
https://ir.lib.uwo.ca/biochempub/218
Autor:
Melissa A. Brown, Dominique Vaur, Sophie Krieger, M. Breault, Laurent Castera, Etienne Rouleau, Eliseos J. Mucaki, Adrien Briaux, Claude Houdayer, Dominique Stoppa-Lyonnet, Sandrine M. Caputo, François Lallemand, M. Gendrot, Peter K. Rogan, E. Santana dos Santos, Leslie Burke, Ivan Bièche
Publikováno v:
Breast Cancer Research and Treatment
Breast Cancer Research and Treatment, Springer Verlag, 2018, 168 (2), pp.311-325. ⟨10.1007/s10549-017-4602-0⟩
Breast Cancer Research and Treatment, Springer Verlag, 2018, 168 (2), pp.311-325. ⟨10.1007/s10549-017-4602-0⟩
International audience; PurposeThe molecular mechanism of breast and/or ovarian cancer susceptibility remains unclear in the majority of patients. While germline mutations in the regulatory non-coding regions of BRCA1 and BRCA2 genes have been descri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c09984d6c1b109728ae3e24eab290f
https://pubmed.ncbi.nlm.nih.gov/29236234
https://pubmed.ncbi.nlm.nih.gov/29236234
Autor:
Jessica Heinemann, Kerry J. Manton, Leslie Burke, Rebecca A. Dawson, Zee Upton, Tony J. Parker, Jacqui A. McGovern, John D. Hooper
Publikováno v:
British Journal of Dermatology. 168:496-503
Background: Epidermogenesis and epidermal wound healing are tightly regulated processes during which keratinocytes must migrate, proliferate and differentiate. Cell to cell adhesion is crucial to the initiation and regulation of these processes. CUB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31866627700bf3d7539e655f73349f7d
https://doi.org/10.1111/bjd.12119
https://doi.org/10.1111/bjd.12119
Autor:
Melissa A. Brown, Etienne Rouleau, Dominique Stoppa-Lyonnet, Leslie Burke, François Lallemand, Sandrine M. Caputo, Elizabeth Santana dos Santos
Publikováno v:
Cancers, Vol 10, Iss 11, p 453 (2018)
Cancers
Cancers
BRCA1 and BRCA2 are major breast cancer susceptibility genes whose pathogenic variants are associated with a significant increase in the risk of breast and ovarian cancers. Current genetic screening is generally limited to BRCA1/2 exons and intron/ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9804a1d35fd335ad6211dbcc6e1f828
https://doi.org/10.3390/cancers10110453
https://doi.org/10.3390/cancers10110453
Publikováno v:
Clinical Interventions in Aging, Vol Volume 4, Pp 31-50 (2008)
Mark A Babizhayev1, Leslie Burke2, Philip Micans3, Stuart P Richer4,51Innovative Vision Products, Inc., County of New Castle, Delaware, USA; 2Wise Choice Products LLC, London, England, United Kingdom; 3IAS Group, Sark, United Kingdom; 4Eye Clinic DVA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7adf33202a08edbb981fa646d5b175e4
https://www.dovepress.com/emnem-acetylcarnosine-sustained-drug-delivery-eye-drops-to-control-the-peer-reviewed-article-CIA
https://www.dovepress.com/emnem-acetylcarnosine-sustained-drug-delivery-eye-drops-to-control-the-peer-reviewed-article-CIA