Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Leslie A. Holladay"'
COMPARATIVE CONFORMATIONAL ANALYSIS OF HUMAN CHORIOMAMMOTROPIN AND SOMATOTROPIN FROM SEVERAL SPECIES
Autor:
David Puett, Leslie A. Holladay
Publikováno v:
International Journal of Peptide and Protein Research. 10:363-368
The conformations of porcine somatotropin and human choriomammotropin have been studied using circular dichroism (CD) and the results compared with spectra of human, murine, ovine, and bovine somatotropin. The far ultraviolet CD spectra of the six pr
Publikováno v:
International Journal of Peptide and Protein Research. 8:183-191
The circular dichroic (CS) spectrum of the glycoprotein hormone, human pituitary luteinizing hormone (hLH), has been determined between 195-320 nm and resolved into gaussian constituents. Below 230 nm the CD spectrum is characterized by a negative ex
Autor:
David Puett, Leslie A. Holladay
Publikováno v:
International Journal of Peptide and Protein Research. 10:102-106
Circular dichroic (CD) spectra of the glycoprotein hormone subunit, lutropin-alpha, have been obtained under denaturing conditions (6 M guanidinium chloride, GdmCl) with the disulfides intact, reduced, and reduced and S-carboxymethylated. Above 260 n
Autor:
Louise M. Temple, Leslie A. Holladay
Publikováno v:
International Journal of Peptide and Protein Research. 25:254-257
A micelle-like polymer of 10-undecenoate was prepared by γ-irradiating micellar solutions in 1 M NH4HCO3. The polymer was characterized with respect to its Stoke's radius, molecular weight, and intrinsic viscosity. The hydrodynamic data are consiste
Publikováno v:
Biochemistry. 49(3)
Efavirenz (EFV) is a nonnucleoside reverse transcriptase inhibitor (NNRTI) of HIV-1 reverse transcriptase (RT) used for the treatment of AIDS. RT is a heterodimer composed of p66 and p51 subunits; p51 is produced from p66 by C-terminal truncation by
Publikováno v:
Biochemistry. 30:7703-7711
The self-association properties of recombinant DNA derived human relaxin, and porcine relaxin isolated from porcine ovaries, have been studied by sedimentation equilibrium analytical ultracentrifugation and circular dichroism (CD). The human relaxin
Publikováno v:
Biochemistry. 45(9)
Recent studies showed that nonnucleoside reverse transcriptase inhibitors (NNRTIs) have variable effects on dimerization of p66 and p51 subunits of HIV-1 reverse transcriptase (RT). Efavirenz, one of three NNRTIs currently used in highly active anti-
Autor:
Leslie A. Holladay, Lenore Kelly
Publikováno v:
Biochemistry. 29(21)
Differential scanning microcalorimetry (DSC) of horse, rat, opossum, raccoon, carp, and armadillo metmyoglobins at alkaline pH gave data that fit the two-state unfolding model well. Monte Carlo studies were used to assess the impact of truncating DSC
Autor:
Leslie A. Holladay, Lenore Kelly
Publikováno v:
Current Research in Protein Chemistry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2666da92677f966aa1426f9bf036e494
https://doi.org/10.1016/b978-0-12-721955-4.50045-2
https://doi.org/10.1016/b978-0-12-721955-4.50045-2
Publikováno v:
Molecular and Cellular Biochemistry. 15:109-116
Human urinary Tamm-Horsfall glycoprotein, which contains 28% carbohydrate, has a monomeric molecular weight of about 80,000 but is isolated from urine in the form of intertwining helical suprastructures with molecular weights greater than 107. The na