Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Leslie, Saurer"'
Autor:
Daniel Zysset, Benjamin Weber, Silvia Rihs, Jennifer Brasseit, Stefan Freigang, Carsten Riether, Yara Banz, Adelheid Cerwenka, Cedric Simillion, Pedro Marques-Vidal, Adrian F. Ochsenbein, Leslie Saurer, Christoph Mueller
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
TREM-1 is a receptor that amplifies acute pro-inflammatory responses in infection. Here the authors show that TREM-1 plays an important role in atherosclerosis, a chronic and non-infectious disease, by critically skewing myelopoiesis towards preferen
Externí odkaz:
https://doaj.org/article/c98d1cb4aaf840bdbe679de4d5413ba5
Autor:
Benjamin Weber, Steffen Schuster, Daniel Zysset, Silvia Rihs, Nina Dickgreber, Christian Schürch, Carsten Riether, Mark Siegrist, Christoph Schneider, Helga Pawelski, Ursina Gurzeler, Pascal Ziltener, Vera Genitsch, Fabienne Tacchini-Cottier, Adrian Ochsenbein, Willy Hofstetter, Manfred Kopf, Thomas Kaufmann, Annette Oxenius, Walter Reith, Leslie Saurer, Christoph Mueller
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003900 (2014)
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-inflammatory innate immune reactions. While TREM-1-amplified responses likely aid an improved detection and elimination of pathogens, excessive production of cytok
Externí odkaz:
https://doaj.org/article/42262ea844a64ff3b8f92dc971b3e0fb
Autor:
Leslie Saurer, Daniel Zysset, Christoph Mueller, Philippe Krebs, Silvia Rihs, Cedric Simillion, Inti Zlobec, Matteo Gusberti, Lukas F. Mager, Alessandro Lugli
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Saurer, Leslie; Zysset, Daniel; Rihs, Silvia; Mager, Lukas; Gusberti, Matteo; Simillion, Cedric; Lugli, Alessandro; Zlobec, Inti; Krebs, Philippe; Müller, Christoph (2017). TREM-1 promotes intestinal tumorigenesis. Scientific Reports, 7(1), p. 14870. Nature Publishing Group 10.1038/s41598-017-14516-4
Scientific Reports
Saurer, Leslie; Zysset, Daniel; Rihs, Silvia; Mager, Lukas; Gusberti, Matteo; Simillion, Cedric; Lugli, Alessandro; Zlobec, Inti; Krebs, Philippe; Müller, Christoph (2017). TREM-1 promotes intestinal tumorigenesis. Scientific Reports, 7(1), p. 14870. Nature Publishing Group 10.1038/s41598-017-14516-4
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-inflammatory innate immune responses. Increasing evidence suggests a role for TREM-1 not only in acute pathogen-induced reactions but also in chronic and non-infec
Autor:
Adelheid Cerwenka, Carsten Riether, Pedro Marques-Vidal, Cedric Simillion, Christoph Mueller, Jennifer Brasseit, Adrian F. Ochsenbein, Yara Banz, Silvia Rihs, Daniel Zysset, Benjamin Weber, Stefan Freigang, Leslie Saurer
Publikováno v:
Zysset, Daniel; Weber, Benjamin; Rihs, Silvia; Brasseit, Jennifer; Freigang, Stefan Bernd; Riether, Carsten; Banz Wälti, Yara; Cerwenka, Adelheid; Simillion, Cedric; Marques-Vidal, Pedro; Ochsenbein, Adrian; Saurer, Leslie; Müller, Christoph (2016). TREM-1 links dyslipidemia to inflammation and lipid deposition in atherosclerosis. Nature communications, 7(13151), p. 13151. Nature Publishing Group 10.1038/ncomms13151
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Nature communications, vol. 7, pp. 13151
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Nature communications, vol. 7, pp. 13151
Triggering receptor expressed on myeloid cells-1 (TREM-1) is a potent amplifier of pro-inflammatory innate immune responses, but its significance in non-infectious diseases remains unclear. Here, we demonstrate that TREM-1 promotes cardiovascular dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5091d293e80f0d36aa5e23c03087ee9c
https://boris.unibe.ch/92033/1/ncomms13151.pdf
https://boris.unibe.ch/92033/1/ncomms13151.pdf
Publikováno v:
European journal of immunology
Intestinal mononuclear phagocytes (iMNP) are critically involved in mucosal immunity and tissue homeostasis. Two major non-overlapping populations of iMNP have been identified in mice. CD103(+) iMNP represent a migratory population capable of inducin
Autor:
Johanna M. Dayer Schneider, Inge Seibold, Nikolina Saxer-Sekulic, Bruno E. Paredes, Leslie Saurer, Christoph Mueller
Publikováno v:
European Journal of Immunology. 39:1743-1753
TNF plays fundamental roles in the induction and perpetuation of inflammation. The effects of TNF are mediated through TNF receptor (TNFR) 1 or 2. As these two receptors mediate different functions, selective targeting of one receptor may represent a
Autor:
Johanna, Dayer Schneider, Inge, Seibold, Nikolina, Saxer-Sekulic, Bruno E, Paredes, Leslie, Saurer, Christoph, Mueller
Publikováno v:
European journal of immunology
TNF plays fundamental roles in the induction and perpetuation of inflammation. The effects of TNF are mediated through TNF receptor (TNFR) 1 or 2. As these two receptors mediate different functions, selective targeting of one receptor may represent a
Autor:
Daniel Zysset, Benjamin Weber, Silvia Rihs, Stefan Freigang, Yara Banz, Leslie Saurer, Christoph Mueller
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 35
TREM-1 is a potent amplifier of pro-inflammatory responses in myeloid cells. While the significance of TREM-1 in acute microbial-induced septic shock has long been acknowledged, our previous studies in experimental models of colitis have also suggest
Autor:
Martin Faderl, Andrew J. Macpherson, Mario Noti, Daniela Finke, Christoph Mueller, Jennifer Brasseit, Hai Li, Vera Genitsch, E. Althaus-Steiner, Wolf-Dietrich Hardt, Tamas Dolowschiak, Leslie Saurer, Kathleen McCoy, Nadia Corazza, Nina Dickgreber
Publikováno v:
Mucosal immunology
Mucosal Immunol
Mucosal Immunol
Current therapies to treat inflammatory bowel diseases have limited efficacy significant side effects and often wane over time. Little is known about the cellular and molecular mechanisms operative in the process of mucosal healing from colitis. To s
Autor:
Anette Sundstedt, Emma J. O’Neill, Leslie Saurer, Kirsty S. Nicolson, David C. Wraith, Ponsford Mary, Graziella Mazza, Steve Anderton, Streeter Heather Barbara
Publikováno v:
Annals of the New York Academy of Sciences. 1029:180-192
Mucosal antigen delivery can induce tolerance, as shown by suppression of subsequent responses to antigen. Our previous work showed that both intranasal and oral routes of antigen delivery were effective but indicated that the intranasal route might