Consistency in the Assessment of Dried Blood Spot Specimen Size and Quality in U.K. Newborn Screening Laboratories

Autor: Stuart J. Moat, James R. Bonham, Christine Cavanagh, Margaret Birch, Caroline Griffith, Lynette Shakespeare, Clare Le Masurier, Claire Manfredonia, Beverly Hird, Philippa Goddard, Sarah Smith, Laura Wainwright, Rachel S. Carling, Jennifer Cundick, Fiona Jenkinson, Catherine Collingwood, Nick Flynn, Nazia Taj, Mehdi Mirzazadeh, Tejswurree Ramgoolam, Liz Robinson, Amy Headley, Tessa Morgan, David Elliman, Lesley Tetlow

Publikováno v: International Journal of Neonatal Screening, Vol 10, Iss 3, p 60 (2024)

In 2015, U.K. newborn screening (NBS) laboratory guidelines were introduced to standardize dried blood spot (DBS) specimen quality acceptance and specify a minimum acceptable DBS diameter of ≥7 mm. The UK ‘acceptable’ avoidable repeat rate (AVR

Externí odkaz: https://doaj.org/article/e1869e2c554c441f999c02d26ed790dd

Notes for the general paediatrician: managing thyrotoxicosis in children and young people

Autor: Marianna Vidouris, Christopher Worth, Leena Patel, Anjali Date, Anas Jasser, Beverly Hird, Lesley Tetlow, Indraneel Banerjee

Publikováno v: BMJ Paediatrics Open. 6:e001582

Thyrotoxicosis due to hyperthyroidism is a serious disorder in childhood often presenting to general paediatricians with a range of clinical manifestations. The commonest cause is Graves’ disease, an autoimmune disorder resulting from thyrotropin r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41cbed6425b1fe28e8a75c269486ff9c
https://doi.org/10.1136/bmjpo-2022-001582

Paediatric reference intervals for plasma anti-Müllerian hormone: comparison of data from the Roche Elecsys assay and the Beckman Coulter Access assay using the same cohort of samples

Autor: Helen M Jopling, Christopher Chaloner, Katharine Hayden, Allen P. Yates, Nicholas J Burgoyne, Lesley Tetlow

Publikováno v: Annals of Clinical Biochemistry

Background Autoanalyser methods for the measurement of anti-Müllerian hormone have been introduced into clinical laboratories but few reports of paediatric reference intervals using these new assays have been published. Methods After prior evaluatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c851d00e5b844b11759cb787948ed31
https://doi.org/10.1177/0004563219830733

Evaluation of 24-h urine containers for urine copper measurement by inductively coupled plasma mass spectrometry

Autor: Anna F Robson, Philip Lockett, Chris M. Chaloner, Lesley Tetlow

Publikováno v: Annals of clinical biochemistry. 57(3)

Objective To determine the necessity for acid-washed containers for 24-h urine copper analysis. Methods Copper solutions, with concentrations relevant to clinical decision limits, were prepared by spiking both assay diluent and unknown urine samples

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e383ae5e3bed7d30e96d898aa7825626
https://pubmed.ncbi.nlm.nih.gov/32208739

Thyroid scintigraphy differentiates subtypes of congenital hypothyroidism

Autor: Lesley Tetlow, Beverly Hird, Leena Patel, Indraneel Banerjee, Neville B. Wright, Chris Worth

Publikováno v: Worth, C, Hird, B, Tetlow, L, Wright, N, Patel, L & Banerjee, I 2019, ' Thyroid scintigraphy differentiates subtypes of congenital hypothyroidism ', Archives of Disease in Childhood, pp. archdischild-2019-317665 . https://doi.org/10.1136/archdischild-2019-317665, https://doi.org/10.1136/archdischild-2019-317665

IntroductionUK screening for congenital hypothyroidism (CH) is based on dried blood spot Thyroid Stimulating Hormone (TSH). Scintigraphy may identify CH subtypes classified as dysplasia, gland in situ (GIS) and ectopia, but is not performed in all ce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1274131480364dba71e637aac27dee63
https://research.manchester.ac.uk/en/publications/571859bb-ecdb-47ad-973c-646e41b1a415