Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Lesley R. de Armas"'
Autor:
Kimberly J. S. Hjelmar, Lesley R. de Armas, Evan Goldberg, Suresh Pallikkuth, Jyoti Mathad, Grace Montepiedra, Amita Gupta, Savita Pahwa
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionLatent tuberculosis infection (LTBI) is a common coinfection in people living with HIV (PWH). How LTBI and HIV exposure in utero influence the development of infant humoral immunity is not well characterized. To address this question, we
Externí odkaz:
https://doaj.org/article/8ee2b51999d7428fa4b23d06e300737f
Autor:
Lesley R. de Armas, Vinh Dinh, Akshay Iyer, Suresh Pallikkuth, Rajendra Pahwa, Nicola Cotugno, Stefano Rinaldi, Paolo Palma, Paula Vaz, Maria Grazia Lain, Savita Pahwa
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109720- (2024)
Summary: In perinatal HIV infection, early antiretroviral therapy (ART) initiation is recommended but questions remain regarding infant immune responses to HIV and its impact on immune development. Using single cell transcriptional and phenotypic ana
Externí odkaz:
https://doaj.org/article/f4de541eeec74b8e95586b91e5b426a7
Autor:
Catherine K. Koofhethile, Stefano Rinaldi, Yelizaveta Rassadkina, Vinh B. Dinh, Ce Gao, Suresh Pallikkuth, Pilar Garcia-Broncano, Lesley R. de Armas, Rajendra Pahwa, Nicola Cotugno, Paula Vaz, Maria Grazia Lain, Paolo Palma, Xu G. Yu, Roger Shapiro, Savita Pahwa, Mathias Lichterfeld
Publikováno v:
International Journal of Infectious Diseases, Vol 127, Iss , Pp 129-136 (2023)
Background: The persistence of HIV-1-infected cells during antiretroviral therapy is well documented but may be modulated by early initiation of antiretroviral therapy in infants. Methods: Here, we longitudinally analyzed the proviral landscape in ni
Externí odkaz:
https://doaj.org/article/b06f070939f546db9fa6cb765ce143d2
Autor:
Lesley R. de Armas, Christina Gavegnano, Suresh Pallikkuth, Stefano Rinaldi, Li Pan, Emilie Battivelli, Eric Verdin, Ramzi T. Younis, Rajendra Pahwa, Siôn L. Williams, Raymond F. Schinazi, Savita Pahwa
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
HIV eradication is hindered by the existence of latent HIV reservoirs in CD4+ T cells. Therapeutic strategies targeting latent cells are required to achieve a functional cure, however the study of latently infected cells from HIV infected persons is
Externí odkaz:
https://doaj.org/article/b429078f0ff24cd3b6a6f5c42081d33b
Autor:
Lesley R. de Armas, Varghese George, Abdelali Filali-Mouhim, Courtney Steel, Anita Parmigiani, Coleen K. Cunningham, Adriana Weinberg, Lydie Trautmann, Rafick-Pierre Sekaly, Mark J. Cameron, Savita Pahwa
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
People living with HIV (PWH) often exhibit poor responses to influenza vaccination despite effective combination anti-retroviral (ART) mediated viral suppression. There exists a paucity of data in identifying immune correlates of influenza vaccine re
Externí odkaz:
https://doaj.org/article/a286879377cd401695cfea1d4274b1f8
Autor:
Catherine K, Koofhethile, Stefano, Rinaldi, Yelizaveta, Rassadkina, Vinh B, Dinh, Ce, Gao, Suresh, Pallikkuth, Pilar, Garcia-Broncano, Lesley R, de Armas, Rajendra, Pahwa, Nicola, Cotugno, Paula, Vaz, Maria Grazia, Lain, Paolo, Palma, Xu G, Yu, Roger, Shapiro, Savita, Pahwa, Mathias, Lichterfeld
Publikováno v:
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
Persistence of HIV-1-infected cells during antiretroviral therapy is well documented, but may be modulated by early initiation of antiretroviral therapy in infants.Here, we longitudinally analyzed the proviral landscape in 9 infants with vertical HIV
Publikováno v:
J Dairy Sci
Gene expression analysis in preimplantation embryos has been used for answering fundamental questions related to development, prediction of pregnancy outcome, and other topics. Limited amounts of mRNA in preimplantation embryos hinders progress in st
Autor:
Suresh Pallikkuth, Paola Zangari, Nicola Cotugno, Paolo Rossi, Ofer Levy, Elena Morrocchi, Stefania Bernardi, Salvatore Rocca, Silvia Di Cesare, Stefano Rinaldi, Paolo Palma, Lesley R. de Armas, Ilaria Pepponi, Savita Pahwa
Publikováno v:
AIDS. 34:669-680
OBJECTIVE To investigate long-term persistence of HIV-specific lymphocyte immunity in perinatally HIV-infected children treated within the first year of life. DESIGN Twenty perinatally HIV-infected children who received ART therapy within the first y
Publikováno v:
AIDS Res Hum Retroviruses
Immune checkpoint molecules (ICMs) regulate T cell responses. In chronic viral infections and cancer, where antigens can persistently stimulate the immune system, ICMs can serve as a barrier to effective immune responses. The role of ICMs in the sett
Autor:
Ryan M McCormack, Lesley R de Armas, Motoaki Shiratsuchi, Desiree G Fiorentino, Melissa L Olsson, Mathias G Lichtenheld, Alejo Morales, Kirill Lyapichev, Louis E Gonzalez, Natasa Strbo, Neelima Sukumar, Olivera Stojadinovic, Gregory V Plano, George P Munson, Marjana Tomic-Canic, Robert S Kirsner, David G Russell, Eckhard R Podack
Publikováno v:
eLife, Vol 4 (2015)
Perforin-2 (MPEG1) is a pore-forming, antibacterial protein with broad-spectrum activity. Perforin-2 is expressed constitutively in phagocytes and inducibly in parenchymal, tissue-forming cells. In vitro, Perforin-2 prevents the intracellular replica
Externí odkaz:
https://doaj.org/article/4d63bfb462a74485b15a3e1f4db4dc01