Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Lesley G, Ellies"'
Autor:
Karen Schmidt, Amber Thatcher, Albert Grobe, Pamela Broussard, Linda Hicks, Haiwei Gu, Lesley G Ellies, Dorothy D. Sears, Leonid Kalachev, Eugene Kroll
Publikováno v:
Translational Medicine Communications, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract Background Many tumors contain hypoxic microenvironments caused by inefficient tumor vascularization. Hypoxic tumors have been shown to resist conventional cancer therapies. Hypoxic cancer cells rely on glucose to meet their energetic and an
Externí odkaz:
https://doaj.org/article/f713ab6a515848e48bd17d0859910209
Autor:
Deepak Kumar, Manasi Das, Alexis Oberg, Debashis Sahoo, Panyisha Wu, Consuelo Sauceda, Lily Jih, Lesley G. Ellies, Magda T. Langiewicz, Supriya Sen, Nicholas J. G. Webster
Publikováno v:
Advanced Science, Vol 9, Iss 21, Pp n/a-n/a (2022)
Abstract Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide. Serine‐arginine rich splicing factor 3 (SRSF3) plays a critical role in hepatocyte function and its loss in mice promotes chronic liver damage and leads to HCC. Hepa
Externí odkaz:
https://doaj.org/article/62d5642666cc412fa26063b587ba6a76
Autor:
Rui Chi, Chengcheng Yao, Si Chen, Yunxia Liu, Yanqi He, Jin Zhang, Lesley G. Ellies, Xuefeng Wu, Qian Zhao, Cixiang Zhou, Ying Wang, Haipeng Sun
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Branched-chain amino acids (BCAAs) are the three essential amino acids including leucine, isoleucine, and valine. BCAA metabolism has been linked with the development of a variety of tumors. However, the impact of dietary BCAA intake on breast tumor
Externí odkaz:
https://doaj.org/article/c14c21b93877442ca7dcda6299be708a
Autor:
Manasi Das, Lesley G. Ellies, Deepak Kumar, Consuelo Sauceda, Alexis Oberg, Emilie Gross, Tyler Mandt, Isabel G. Newton, Mehak Kaur, Dorothy D. Sears, Nicholas J. G. Webster
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Obesity and its associated metabolic changes, including hyperinsulinemia and aberrant circadian rhythms, increases the risk for a variety of cancers including postmenopausal breast cancer. Here, the authors show that restricting when mice eat, but no
Externí odkaz:
https://doaj.org/article/a2944ae436f340f4a94b7c20729f5a09
Autor:
Todd A. Aguilera, Marjan Rafat, Laura Castellini, Hussein Shehade, Mihalis S. Kariolis, Angela Bik-Yu Hui, Henning Stehr, Rie von Eyben, Dadi Jiang, Lesley G. Ellies, Albert C. Koong, Maximilian Diehn, Erinn B. Rankin, Edward E. Graves, Amato J. Giaccia
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Radiotherapy can enhance the antitumour immune response. Here, the authors show that resistance to radiation in breast cancer cells can be due to Axl expression that suppresses antigen presentation though MHCI, promotes NF-κB signalling, and enhance
Externí odkaz:
https://doaj.org/article/d32eb98fd69f4bdf897a2cd00a59903c
Autor:
Roger Y. Tsien, Michael A. Whitney, Lesley G. Ellies, Heather L. Glasgow, Elamprakash N. Savariar, Jessica L. Crisp
PDF file - 5319K, Supplementary Materials and Methods. Supplemental Table 1: List of peptides and synthetic intermediates with corresponding molecular weights. Supplemental Figure 1: Chemical Structure of dual targeted peptides. Supplemental Figure 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d82c186deef477dff5e7188c531dd5
https://doi.org/10.1158/1535-7163.22500130
https://doi.org/10.1158/1535-7163.22500130
Autor:
Roger Y. Tsien, Michael A. Whitney, Lesley G. Ellies, Heather L. Glasgow, Elamprakash N. Savariar, Jessica L. Crisp
Activatable cell-penetrating peptides (ACPP) provide a general strategy for molecular targeting by exploiting the extracellular protease activities associated with disease. Previous work used a matrix metalloproteinase (MMP-2 and 9)-cleavable sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6510bcc22ad9f595fdf165ad034a05e0
https://doi.org/10.1158/1535-7163.c.6536365.v1
https://doi.org/10.1158/1535-7163.c.6536365.v1
Autor:
Amato J. Giaccia, Edward E. Graves, Erinn B. Rankin, Lesley G. Ellies, Quynh-Thu Le, Albert C. Koong, Mihalis Kariolis, Dadi Jiang, Laura Castellini, Marjan Rafat, Hussein Shehade, Eslam A. Elghonaimy, Todd A. Aguilera
Purpose:To investigate how induced tumor heterogeneity influences immune responses to radiotherapy with different proportions of mixed immune-responsive and unresponsive tumor cells in a triple-negative breast cancer model. It is hypothesized that st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8c119995e2e237cdebf8f277cf7467
https://doi.org/10.1158/1078-0432.c.6529362
https://doi.org/10.1158/1078-0432.c.6529362
Autor:
Amato J. Giaccia, Edward E. Graves, Erinn B. Rankin, Lesley G. Ellies, Quynh-Thu Le, Albert C. Koong, Mihalis Kariolis, Dadi Jiang, Laura Castellini, Marjan Rafat, Hussein Shehade, Eslam A. Elghonaimy, Todd A. Aguilera
supplementary tables 1-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33d9ac223c1e0b038544686935b44fd5
https://doi.org/10.1158/1078-0432.22476285.v1
https://doi.org/10.1158/1078-0432.22476285.v1
Autor:
Amato J. Giaccia, Edward E. Graves, Erinn B. Rankin, Lesley G. Ellies, Quynh-Thu Le, Albert C. Koong, Mihalis Kariolis, Dadi Jiang, Laura Castellini, Marjan Rafat, Hussein Shehade, Eslam A. Elghonaimy, Todd A. Aguilera
Supplementary legends and figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10bd4473f2e52451d1cd41a0e73e5ff3
https://doi.org/10.1158/1078-0432.22476288.v1
https://doi.org/10.1158/1078-0432.22476288.v1