Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Lesley C. McFarlane"'
Autor:
Lesley C. McFarlane, Thomas C. Fardon, Caroline E. Bates, K. Haggart, Brian J. Lipworth, Daniel K. C. Lee
Publikováno v:
Chest. 127:851-860
There are no data comparing the relative effects of high-dose ciclesonide (CIC) and fluticasone propionate (FP) on airway and systemic outcomes in patients with moderate persistent asthma.We elected to evaluate the relative effects of CIC and FP on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e438cabc7341f05a248dbb72fd70e557
https://doi.org/10.1378/chest.127.3.851
https://doi.org/10.1378/chest.127.3.851
Autor:
Erika J. Sims, Graeme P. Currie, Daniel K. C. Lee, Brian J. Lipworth, F.M. Robb, Lesley C. McFarlane
Publikováno v:
British Journal of Clinical Pharmacology. 55:310-313
Aims To evaluate the systemic bioactivity of triamcinolone acetonide (TA) 220 µg or mometasone furoate (MF) 200 µg over 3 weeks in perennial allergic rhinitis. Methods Twenty-seven patients received TA 220 µg or MF 200 µg once daily for 3 weeks w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c869f8e803d3fa910d6fde26b3cc079
https://doi.org/10.1046/j.1365-2125.2003.01729.x
https://doi.org/10.1046/j.1365-2125.2003.01729.x
Therapeutic Ratio of Hydrofluoroalkane and Chlorofluorocarbon Formulations of Fluticasone Propionate
Autor:
Lesley C. McFarlane, Linda C. Orr, Erika J. Sims, Graeme P. Currie, Brian J. Lipworth, Andrew M. Wilson, Stephen J. Fowler
Publikováno v:
Chest. 122:618-623
Objectives To compare the therapeutic ratio of chlorofluorocarbon (CFC) and hydrofluoroalkane-134a (HFA) formulations of fluticasone propionate (FP). Methods We performed a randomized, placebo-controlled, crossover study comparing 6 weeks of treatmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218c772c0cffbb271d42abbf80d40ada
https://doi.org/10.1378/chest.122.2.618
https://doi.org/10.1378/chest.122.2.618
Publikováno v:
Chest. 114:1022-1027
Because nebulized budesonide may be used as an alternative to maintenance oral prednisolone in the treatment of severe chronic asthma, it is important to compare these two drugs to determine their relative systemic bioactivity profiles in terms of ef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d0eb0ca43021a1925991712bac8d1c7
https://doi.org/10.1378/chest.114.4.1022
https://doi.org/10.1378/chest.114.4.1022
Publikováno v:
Journal of Allergy and Clinical Immunology. 101:470-474
Intranasal corticosteroids are regarded as the first-line treatment for allergic rhinitis, but few studies have directly compared their systemic effects.We sought to compare the hypothalamic-pituitary-adrenal (HPA)-axis suppression with three intrana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2d559a7ceb008f521a92bd8ee981c1c
https://doi.org/10.1016/s0091-6749(98)70354-9
https://doi.org/10.1016/s0091-6749(98)70354-9
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:922-925
The objective of this study was to evaluate the effects of inhaled flunisolide (FN) and triamcinolone acetonide (TAA) on basal and dynamic adrenocortical activity. A randomized cross-over design was used, comparing placebo (PL), low (L) and high (H)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847d5bf684da03482be86fe528a61878
https://doi.org/10.1210/jcem.83.3.4637
https://doi.org/10.1210/jcem.83.3.4637
Publikováno v:
Thorax. 52:608-611
BACKGROUND: A study was undertaken to investigate the influence of the menstrual cycle on airway responsiveness and beta 2 adrenoceptor function in female asthmatic patients. It has previously been shown that normal women exhibit cyclical changes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21ed08dcf724155ec49283183063a523
https://doi.org/10.1136/thx.52.7.608
https://doi.org/10.1136/thx.52.7.608
Publikováno v:
Chest. 109:343-347
The aim of the study was to evaluate the facilitatory effects of inhaled corticosteroid on in vitro parameters of lymphocyte beta 2-adrenoceptor function in asthmatic patients. Serum cortisol level was also evaluated as a measure of systemic bioactiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965f9b2a91f6be46c14e57e3d10ef719
https://doi.org/10.1378/chest.109.2.343
https://doi.org/10.1378/chest.109.2.343
Publikováno v:
European Journal of Applied Physiology and Occupational Physiology. 72:256-260
We have studied the integrated neuroendocrine and haemodynamic effects of acute hypoxaemia in ten healthy volunteers studied on two separate occasions. After reaching a resting haemodynamic state, subjects breathed either room air or a nitrogen/oxyge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b746103a292ecb6b20e9b7e38adf23f9
https://doi.org/10.1007/bf00838648
https://doi.org/10.1007/bf00838648
Autor:
Brian J. Lipworth, K. L. Clearie, Daniel Menzies, Arun Nair, Karen Meldrum, Lesley C. McFarlane
Publikováno v:
Pulmonary pharmacologytherapeutics. 22(4)
Background Spacer devices facilitate respirable drug delivery. A novel breath-actuated antistatic spacer with integrated vortex chamber (Synchro-Breathe™) device has been developed, which is compact, portable and user friendly as compared to conven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9aebeaf814c93db7387a19d9937344c6
https://pubmed.ncbi.nlm.nih.gov/19489129
https://pubmed.ncbi.nlm.nih.gov/19489129