Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Lesley A. Mathews"'
Autor:
Dandan Li, Anne M. Miermont, Rushikesh Sable, Humair S. Quadri, Lesley A. Mathews Griner, Scott E. Martin, Taivan Odzorig, Soumita De, Marc Ferrer, Astin S. Powers, Stephen M. Hewitt, Udo Rudloff
Publikováno v:
Molecular Cancer Research. 21:316-331
Combinatorial molecular therapy in pancreatic ductal adenocarcinoma (PDAC) has yielded largely disappointing results in clinical testing to-date as a multitude of adaptive resistance mechanisms is making selection of patients via molecular markers th
Autor:
Kevin J. Frankowski, Samarjit Patnaik, Chen Wang, Noel Southall, Dipannita Dutta, Soumitta De, Dandan Li, Christopher Dextras, Yi-Han Lin, Marthe Bryant-Connah, Danielle Davis, Feijun Wang, Leah M. Wachsmuth, Pranav Shah, Jordan Williams, Md Kabir, Edward Zhu, Bolormaa Baljinnyam, Amy Wang, Xin Xu, John Norton, Marc Ferrer, Steve Titus, Anton Simeonov, Wei Zheng, Lesley A. Mathews Griner, Ajit Jadhav, Jeffrey Aubé, Mark J. Henderson, Udo Rudloff, Frank J. Schoenen, Sui Huang, Juan J. Marugan
Publikováno v:
J Med Chem
The perinucleolar compartment (PNC) is a dynamic subnuclear body found at the periphery of the nucleolus. The PNC is enriched with RNA transcripts and RNA-binding proteins, reflecting different states of genome organization. PNC prevalence positively
Akademický článek
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Autor:
Udo Rudloff, Stephen M. Hewitt, Astin S. Powers, Marc Ferrer, Soumita De, Taivan Odzorig, Scott E. Martin, Lesley A. Mathews Griner, Humair S. Quadri, Rushikesh Sable, Anne M. Miermont, Dandan Li
Secondary validation of candidate genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe0202c8c1b1c2f47cd5bfd9278fde5
https://doi.org/10.1158/1541-7786.22552189
https://doi.org/10.1158/1541-7786.22552189
Autor:
Udo Rudloff, Stephen M. Hewitt, Astin S. Powers, Marc Ferrer, Soumita De, Taivan Odzorig, Scott E. Martin, Lesley A. Mathews Griner, Humair S. Quadri, Rushikesh Sable, Anne M. Miermont, Dandan Li
Lists of cell lines, antibodies, RNAi kinome screen; and matrix drug combination.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da43ec6520c5ea5999715ba8cfa37149
https://doi.org/10.1158/1541-7786.22552171.v1
https://doi.org/10.1158/1541-7786.22552171.v1
Autor:
Udo Rudloff, Craig J. Thomas, Marc Ferrer, Jeffrey Aubé, Steven A. Rogers, Paresma Patel, Jian-kang Jiang, Dandan Li, Astin S. Powers, Holger Pflicke, Hong-Wu Xin, Paul Shinn, Rajarshi Guha, Vivek Shukla, Taylor J. Aiken, Lesley A. Mathews Griner, Yaroslav Teper, Yansong Bian
Suppl. Fig. 1: Procedures for synthesis of NCGC00188382 (Inhibitor#1) Suppl. Fig. 2: qPCR array of 96 stem cell genes from PANC1 adherent and PANC1 spheroids reveal up-regulation of six stem cell genes in organotypic Panc1 spheres. Suppl. Fig. 3: Inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a29c837ea26c77693a9c700ef66f4593
https://doi.org/10.1158/1535-7163.22506210.v1
https://doi.org/10.1158/1535-7163.22506210.v1
Autor:
Udo Rudloff, Craig J. Thomas, Marc Ferrer, Jeffrey Aubé, Steven A. Rogers, Paresma Patel, Jian-kang Jiang, Dandan Li, Astin S. Powers, Holger Pflicke, Hong-Wu Xin, Paul Shinn, Rajarshi Guha, Vivek Shukla, Taylor J. Aiken, Lesley A. Mathews Griner, Yaroslav Teper, Yansong Bian
Pancreatic cancer remains an incurable condition. Its progression is driven, in part, by subsets of cancer cells that evade the cytotoxic effects of conventional chemotherapies. These cells are often low-cycling, multidrug resistant, and adopt a stem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e21950819e835c195e9bc54f304d464
https://doi.org/10.1158/1535-7163.c.6538326
https://doi.org/10.1158/1535-7163.c.6538326
Autor:
Udo Rudloff, Craig J. Thomas, Marc Ferrer, Jeffrey Aubé, Steven A. Rogers, Paresma Patel, Jian-kang Jiang, Dandan Li, Astin S. Powers, Holger Pflicke, Hong-Wu Xin, Paul Shinn, Rajarshi Guha, Vivek Shukla, Taylor J. Aiken, Lesley A. Mathews Griner, Yaroslav Teper, Yansong Bian
Suppl. Table 1. Origin of cancer cell lines used in this study. Suppl. Table 2. Quantitative HTS screen in PANC1 cells grown as spheroids. Results of full ten concentration drug-response curves of 1,912 individual agents and compounds in PANC1 sphero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82e4ba4ea7ca0eeb8db75195a3876a14
https://doi.org/10.1158/1535-7163.22506207.v1
https://doi.org/10.1158/1535-7163.22506207.v1
Autor:
Udo Rudloff, Craig J. Thomas, Marc Ferrer, Jeffrey Aubé, Steven A. Rogers, Paresma Patel, Jian-kang Jiang, Dandan Li, Astin S. Powers, Holger Pflicke, Hong-Wu Xin, Paul Shinn, Rajarshi Guha, Vivek Shukla, Taylor J. Aiken, Lesley A. Mathews Griner, Yaroslav Teper, Yansong Bian
Suppl. Table 1. Origin of cancer cell lines used in this study. Suppl. Table 2. Quantitative HTS screen in PANC1 cells grown as spheroids. Results of full ten concentration drug-response curves of 1,912 individual agents and compounds in PANC1 sphero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7ee27a7001f1e291a06f5655cfed31
https://doi.org/10.1158/1535-7163.22506213
https://doi.org/10.1158/1535-7163.22506213
Autor:
Darrin D. Stuart, William R. Sellers, Savithri Ramurthy, Emma Lees, Michael P. Dillon, Nicholas Keen, Mallika Singh, Payman Amiri, Mohammad Hekmat-Nejad, Richard Zang, Valery Polyakov, Robert Aversa, Jacob R. Haling, John Tellew, Alice Rico, Gisele Nishiguchi, Lesley A. Mathews Griner, Joshua M. Korn, Fang Shen, Yingyun Wang, Stacy Rivera, Vesselina G. Cooke, Giordano Caponigro, Yun Feng, Yuji M. Mishina, Wenlin Shao
Antiproliferative effect of RAF709 compared to dabrafenib, trametinib, RAF265 and sorafenib across a tumor cell panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df399afb7bc4b33e7cbabf7feb9002be
https://doi.org/10.1158/0008-5472.22417724
https://doi.org/10.1158/0008-5472.22417724