Comparing Intubation Rates in Patients Receiving Parenteral Olanzapine With and Without a Parenteral Benzodiazepine in the Emergency Department

Autor: Cole, Jon B. ^{a, b, ∗}, Stang, Jamie L. ^{a, b}, Collins, Jacob D. ^a, Klein, Lauren R. ^a, DeVries, Paige A. ^{a, c}, Smith, Jennifer ^d, Pepin, Lesley C. ^{a, b}, Fuchs, Ryan T. ^{a, b}, Driver, Brian E. ^{a, b}

Publikováno v: In Annals of Emergency Medicine December 2024 84(6):658-667

Narrowing the diagnostic gap: Genomes, episignatures, long-read sequencing, and health economic analyses in an exome-negative intellectual disability cohort

Autor: Dias, Kerith-Rae ^{1, 2}, Shrestha, Rupendra ³, Schofield, Deborah ³, Evans, Carey-Anne ^{1, 4}, O’Heir, Emily ⁵, Zhu, Ying ^{1, 4, 6}, Zhang, Futao ^{1, 4}, Standen, Krystle ⁴, Weisburd, Ben ⁵, Stenton, Sarah L. ⁵, Sanchis-Juan, Alba ⁵, Brand, Harrison ⁵, Talkowski, Michael E. ⁵, Ma, Alan ^{7, 8}, Ghedia, Sondy ^{9, 10}, Wilson, Meredith ⁷, Sandaradura, Sarah A. ^{7, 11}, Smith, Janine ^{7, 8}, Kamien, Benjamin ^{12, 13}, Turner, Anne ¹⁴, Bakshi, Madhura ¹⁵, Adès, Lesley C. ^{7, 11}, Mowat, David ^{14, 16}, Regan, Matthew ¹⁷, McGillivray, George ¹⁸, Savarirayan, Ravi ^{18, 19, 20}, White, Susan M. ^{18, 20}, Tan, Tiong Yang ^{18, 19, 20}, Stark, Zornitza ^{18, 20, 21}, Brown, Natasha J. ^{18, 19, 20}, Pérez-Jurado, Luis A. ^{22, 23}, Krzesinski, Emma ^{17, 24}, Hunter, Matthew F. ^{17, 24}, Akesson, Lauren ^{25, 26, 27}, Fennell, Andrew Paul ^{17, 24}, Yeung, Alison ^{18, 19, 20}, Boughtwood, Tiffany ^{19, 21}, Ewans, Lisa J. ^{14, 16, 28}, Kerkhof, Jennifer ²⁹, Lucas, Christopher ⁴, Carey, Louise ⁴, French, Hugh ³⁰, Rapadas, Melissa ^{28, 31}, Stevanovski, Igor ^{28, 31}, Deveson, Ira W. ^{28, 31, 32}, Cliffe, Corrina ⁴, Elakis, George ⁴, Kirk, Edwin P. ^{4, 14, 16}, Dudding-Byth, Tracy ⁶, Fletcher, Janice ⁴, Walsh, Rebecca ⁴, Corbett, Mark A. ³³, Kroes, Thessa ³³, Gecz, Jozef ^{33, 34}, Meldrum, Cliff ³⁵, Cliffe, Simon ³⁵, Wall, Meg ¹⁸, Lunke, Sebastian ¹⁸, North, Kathryn ^{19, 20, 21, 36}, Amor, David J. ^{19, 20}, Field, Michael ⁶, Sadikovic, Bekim ^{29, 37}, Buckley, Michael F. ⁴, O’Donnell-Luria, Anne ^{5, 38}, Roscioli, Tony ^{1, 2, 4, ∗}

Publikováno v: In Genetics in Medicine May 2024 26(5)

Large libraries of single-chain trimer peptide-MHCs enable antigen-specific CD8+ T cell discovery and analysis

Autor: William Chour, Jongchan Choi, Jingyi Xie, Mary E. Chaffee, Thomas M. Schmitt, Kathryn Finton, Diana C. DeLucia, Alexander M. Xu, Yapeng Su, Daniel G. Chen, Rongyu Zhang, Dan Yuan, Sunga Hong, Alphonsus H. C. Ng, Jonah Z. Butler, Rick A. Edmark, Lesley C. Jones, Kim M. Murray, Songming Peng, Guideng Li, Roland K. Strong, John K. Lee, Jason D. Goldman, Philip D. Greenberg, James R. Heath

Publikováno v: Communications Biology, Vol 6, Iss 1, Pp 1-13 (2023)

Abstract The discovery and characterization of antigen-specific CD8+ T cell clonotypes typically involves the labor-intensive synthesis and construction of peptide-MHC tetramers. We adapt single-chain trimer (SCT) technologies into a high throughput

Externí odkaz: https://doaj.org/article/3bdea162be0a4447904d5af92d6a6730

Clinical factors associated with late seizure remission after failed epilepsy surgery

Autor: Kaye, Lesley C. ^a, Poolos, Zoe A. ^b, Miller, John W. ^c, Poolos, Nicholas P. ^{c, ⁎}

Publikováno v: In Epilepsy & Behavior January 2023 138

Stressors Among Healthcare Workers: A Summative Content Analysis

Autor: Lesley C. Rink, Tolu O. Oyesanya, Kathryn C. Adair, Janice C. Humphreys, Susan G. Silva, John Bryan Sexton

Publikováno v: Global Qualitative Nursing Research, Vol 10 (2023)

Healthcare workers are experiencing high stress and burnout, at rates up to 70%, hindering patient care. Studies often focus on stressors in a particular setting or within the context of the pandemic which limits understanding of a more comprehensive

Externí odkaz: https://doaj.org/article/a429bef7c9df45968025abd6278a0560