Novel insights into regulation of Target of Rapamycin Complex 2 by hyperosmotic stress

Autor: Leskoske, KL, Roelants, FM, Thorner, JW

Publikováno v: MOLECULAR BIOLOGY OF THE CELL, vol 27
Leskoske, KL; Roelants, FM; & Thorner, JW. (2016). Novel insights into regulation of Target of Rapamycin Complex 2 by hyperosmotic stress.. MOLECULAR BIOLOGY OF THE CELL, 27. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/0t0886rm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::29f435e8446883b8da4255b2ec1b0907
https://escholarship.org/uc/item/0t0886rm

Subgroup-Enriched Pathways and Kinase Signatures in Medulloblastoma Patient-Derived Xenografts.

Autor: Leskoske KL; Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, United States., Garcia-Mansfield K; Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, United States.; Integrated Mass Spectrometry Shared Resource, City of Hope Comprehensive Cancer Center, Duarte, California 91010, United States., Sharma R; Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, United States.; Integrated Mass Spectrometry Shared Resource, City of Hope Comprehensive Cancer Center, Duarte, California 91010, United States., Krishnan A; Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, United States., Rusert JM; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California 92037, United States., Mesirov JP; Department of Medicine, University of California San Diego, La Jolla, California 92093, United States.; Moores Cancer Center, University of California San Diego, La Jolla, California 92093, United States., Wechsler-Reya RJ; Tumor Initiation and Maintenance Program, NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California 92037, United States., Pirrotte P; Cancer and Cell Biology Division, Translational Genomics Research Institute, Phoenix, Arizona 85004, United States.; Integrated Mass Spectrometry Shared Resource, City of Hope Comprehensive Cancer Center, Duarte, California 91010, United States.

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Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2.

Autor: Leskoske KL; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA., Roelants FM; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA., Emmerstorfer-Augustin A; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA., Augustin CM; Department of Mechanical Engineering, University of California at Berkeley, Berkeley, California 94720, USA., Si EP; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA., Hill JM; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA., Thorner J; Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720, USA.

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The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites.

Autor: Leskoske KL; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202.; Division of Cell and Developmental Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202., Roelants FM; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202.; Division of Cell and Developmental Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202., Martinez Marshall MN; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202.; Division of Cell and Developmental Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202., Hill JM; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202.; Division of Cell and Developmental Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202., Thorner J; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202 jthorner@berkeley.edu.; Division of Cell and Developmental Biology, Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202 jthorner@berkeley.edu.

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Down-regulation of TORC2-Ypk1 signaling promotes MAPK-independent survival under hyperosmotic stress.

Autor: Muir A; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States., Roelants FM; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States., Timmons G; Department of Chemistry, University of California, Berkeley, Berkeley, United States., Leskoske KL; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States., Thorner J; Division of Biochemistry, Biophysics and Structural Biology, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.

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