Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Lesia O. Kurlak"'
Autor:
Lesia O. Kurlak, Paula J. Scaife, Louise V. Briggs, Fiona Broughton Pipkin, David S. Gardner, Hiten D. Mistry
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3579 (2023)
Trace elements such as selenium and zinc are vital components of many enzymes, including endogenous antioxidants, and can interact with each other. Women with pre-eclampsia, the hypertensive disease of pregnancy, have been reported as having changes
Externí odkaz:
https://doaj.org/article/a531ec86268449478cf5bcf979b8f2a1
Autor:
Kate Wiles, Kate Bramham, Paul T. Seed, Lesia O. Kurlak, Hiten D. Mistry, Catherine Nelson-Piercy, Liz Lightstone, Lucy C. Chappell
Publikováno v:
Kidney International Reports, Vol 4, Iss 6, Pp 842-853 (2019)
Introduction: Diagnosis of superimposed preeclampsia in women with chronic kidney disease (CKD) is complicated by the presence of hypertension and proteinuria due to renal disease. The aims of this study were to determine mechanistic links between su
Externí odkaz:
https://doaj.org/article/ff28a4d3b14346578ec828387ee87947
Autor:
Hiten D. Mistry, Melissa V. Hott Ogalde, Fiona Broughton Pipkin, Geneviève Escher, Lesia O. Kurlak
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Selectins [endothelial (E), platelet (P), and leucocytes (L)] are a class of cell adhesion molecules, stimulated in response to inflammation. Pre-eclampsia is characterized by inflammation, and angiotensin II is pro-inflammatory. We hypothesized that
Externí odkaz:
https://doaj.org/article/ec718fcf3b234b7c923195b600f9951a
Autor:
Kimberly Seamon, Lesia O. Kurlak, Michelle Warthan, Efstratios Stratikos, Jerome F. Strauss, Hiten D. Mistry, Eun D. Lee
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Pre-eclampsia (PE) is a disorder of pregnancy, often leading to serious and fatal complications. Endoplasmic reticulum aminopeptidase 1 and 2 (ERAP1/ERAP2) are present in the placenta. They are involved in processes regulating blood pressure, angioge
Externí odkaz:
https://doaj.org/article/c435f091b8e04e4bbe440f07876f3f4a
Autor:
Paula J. Scaife, Amy Simpson, Lesia O. Kurlak, Louise V. Briggs, David S. Gardner, Fiona Broughton Pipkin, Carolyn J. P. Jones, Hiten D. Mistry
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 14, p 7295 (2021)
Up to 11% of pregnancies extend to post-term with adverse obstetric events linked to pregnancies over 42 weeks. Oxidative stress and senescence (cells stop growing and dividing by irreversibly arresting their cell cycle and gradually ageing) can resu
Externí odkaz:
https://doaj.org/article/814c018ca0da46f8a8afad0da8e246ff
Autor:
Hiten D. Mistry, Lesia O. Kurlak, Yosef T. Mansour, Line Zurkinden, Markus G. Mohaupt, Geneviève Escher
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1186-1195 (2017)
Preeclampsia is a pregnancy-specific condition that leads to increased cardiovascular risk in later life. A decrease in cholesterol efflux capacity is linked to CVD. We hypothesized that in preeclampsia there would be a disruption of maternal/fetal p
Externí odkaz:
https://doaj.org/article/d8f7e66350144491ab19250f45cf463b
Autor:
Hiten D. Mistry, Lesia O. Kurlak, David S. Gardner, Ole Torffvit, Alastair Hansen, Fiona Broughton Pipkin, Helena Strevens
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 13 (2019)
Background AGT (angiotensinogen) synthesis occurs in renal proximal tubular epithelial cells, independent from systemic AGT, as a component of the intrarenal renin–angiotensin system. We investigated urinary AGT, as a biomarker for renin–angioten
Externí odkaz:
https://doaj.org/article/b242e4446ea743f5baa2667629c032e5
Autor:
Marta R. Hentschke, Carlos E. Poli-de-Figueiredo, Bartira E. Pinheiro da Costa, Lesia O. Kurlak, Paula J. Williams, Hiten D. Mistry
Publikováno v:
Journal of Lipid Research, Vol 54, Iss 10, Pp 2658-2664 (2013)
Atherosis of spiral arteries in uteroplacental beds from preeclamptic women resemble those of atherosclerosis, characterized by increased plasma lipids and lipoproteins. We hypothesized that: 1) lipoprotein receptors/transporters in the placenta woul
Externí odkaz:
https://doaj.org/article/35a5675a0b3a4dd4a998d16654fd9947
Publikováno v:
Placenta. 134:9-14
Autor:
Hiten D. Mistry, Rahel Klossner, Sampada Kallol, Michael P. Lüthi, Ruedi Moser, Henning Schneider, Edgar C. Ontsouka, Lesia O. Kurlak, Markus G. Mohaupt, Christiane Albrecht
Publikováno v:
Mistry, Hiten D; Klossner, Rahel; Kallol, Sampada; Lüthi, Michael P; Moser, Ruedi; Schneider, Henning; Ontsouka, Edgar C; Kurlak, Lesia O; Mohaupt, Markus G.; Albrecht, Christiane (2022). Effects of aldosterone on the human placenta: Insights from placental perfusion studies. Placenta, 123, pp. 32-40. Elsevier 10.1016/j.placenta.2022.03.129
INTRODUCTION In pregnancy, aldosterone is linked to maternal plasma volume expansion, improved fetal and placental growth/angiogenesis and reduced maternal blood pressure. Aldosterone levels are low in women with pre-eclampsia. Given the placental gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb1e9b71e0899da568ac28482cb6066
https://boris.unibe.ch/169908/1/1-s2.0-S0143400422002156-main.pdf
https://boris.unibe.ch/169908/1/1-s2.0-S0143400422002156-main.pdf