Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Lesi Cai"'
Autor:
Shiwei Qumu, Weiliang Sun, Jing Guo, Yuting Zhang, Lesi Cai, Chaozeng Si, Xia Xu, Lulu Yang, Xuanming Situ, Tianyi Yang, Jiaze He, Minghui Shi, Dongyan Liu, Xiaoxia Ren, Ke Huang, Hongtao Niu, Hong Li, Chang’An Yu, Yang Chen, Ting Yang, Ningning Wang
Publikováno v:
Chinese Medical Journal, Vol 136, Iss 4, Pp 461-472 (2023)
Abstract. Background:. Exercise, as the cornerstone of pulmonary rehabilitation, is recommended to chronic obstructive pulmonary disease (COPD) patients. The underlying molecular basis and metabolic process were not fully elucidated. Methods:. Spragu
Externí odkaz:
https://doaj.org/article/f9f5c6f3fb69419195bdf9a8128654ee
Autor:
Yang Chen, Hansen Zhao, Weiliang Sun, Xinrong Zhang, Lin Pan, Si Yu, Shao Li, Minglei Shi, Shiwei Qumu, Lesi Cai, Yongchang Zheng, Zhiyuan Yuan, Michael Q. Zhang, Qiming Zhou, Jiaxin Feng
Publikováno v:
Nature Methods. 18:1223-1232
Spatial metabolomics can reveal intercellular heterogeneity and tissue organization. Here we report on the spatial single nuclear metabolomics (SEAM) method, a flexible platform combining high-spatial-resolution imaging mass spectrometry and a set of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d74b40b9e0348198f3cdb13f27b8e03c
https://doi.org/10.1038/s41592-021-01276-3
https://doi.org/10.1038/s41592-021-01276-3
Publikováno v:
The Analyst. 145:6901-6909
Skeletal muscle tissue is composed of various muscle cell types which differ in physiological functions. Changes in cell type composition of skeletal muscle are associated with the development of metabolic diseases. Skeletal muscle cell types are cur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e12ce4ff50200d3ead96eb40a8dcb5c
https://doi.org/10.1039/d0an00738b
https://doi.org/10.1039/d0an00738b
Publikováno v:
Analytical Chemistry. 91:9168-9173
5-Carboxylfluorescein (FAM) is a conventional pH-responsive fluorophore widely used in fluorescence labeling and imaging. Because of its nonfluorescent structure under acidic conditions, FAM has long been limited to pH determination in a neutral–ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5edaf6b2450043540e3aeaa46ae74e9c
https://doi.org/10.1021/acs.analchem.9b01864
https://doi.org/10.1021/acs.analchem.9b01864
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9baddabc98b4710e9692d1e8f89ad54f
https://doi.org/10.2139/ssrn.3990745
https://doi.org/10.2139/ssrn.3990745
Publikováno v:
Microchemical Journal. 177:107303
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcfdc0b9456885b82ab76a8ac345da63
https://doi.org/10.1016/j.microc.2022.107303
https://doi.org/10.1016/j.microc.2022.107303
Autor:
Michael Zhang, Zhiyuan Yuan, Qiming Zhou, Lesi Cai, Lin Pan, Weiliang Sun, Shiwei Qumu, Si Yu, Yongchang Zheng, Shao Li, Yang Chen, Xinrong Zhang
Spatial metabolomics can reveal intercellular heterogeneity and tissue organization. To achieve highest spatial resolution, we reported a novel Spatial single nuclEar metAboloMics (SEAM) method, a scalable platform combining high resolution imaging m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2dd9bf2685a640eb9d65c560732bb1f
https://doi.org/10.21203/rs.3.rs-63938/v1
https://doi.org/10.21203/rs.3.rs-63938/v1
Autor:
Zhiyuan, Yuan, Qiming, Zhou, Lesi, Cai, Lin, Pan, Weiliang, Sun, Shiwei, Qumu, Si, Yu, Jiaxin, Feng, Hansen, Zhao, Yongchang, Zheng, Minglei, Shi, Shao, Li, Yang, Chen, Xinrong, Zhang, Michael Q, Zhang
Publikováno v:
Nature methods. 18(10)
Spatial metabolomics can reveal intercellular heterogeneity and tissue organization. Here we report on the spatial single nuclear metabolomics (SEAM) method, a flexible platform combining high-spatial-resolution imaging mass spectrometry and a set of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0b5296a84773ff8352ebe9ae0120f76
https://pubmed.ncbi.nlm.nih.gov/34608315
https://pubmed.ncbi.nlm.nih.gov/34608315
Autor:
Zeper Abliz, Xinrong Zhang, Ruiping Zhang, Sichun Zhang, Chenglong Sun, Yuxiang Mo, Feng Liu, Lesi Cai, Zhaoying Wang, Jia Wang
Publikováno v:
International Journal of Mass Spectrometry. 432:9-13
A new instrument based on VUV laser desorption/ionization (VUVDI) method was used to measure the mass spectrum of the cholesterol standard and the mass spectrometry images (MSI) of intact cholesterol in a mouse esophagus tissue section and mouse zygo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edff9ceed090dcc12c515c5b3da16802
https://doi.org/10.1016/j.ijms.2018.06.008
https://doi.org/10.1016/j.ijms.2018.06.008
Autor:
Zhaoying Wang, Feng Liu, Sichun Zhang, Xinrong Zhang, Hong-Yuan Chen, Jia Wang, Lesi Cai, Zhanping Li, Jian-Bin Pan, Yuxiang Mo
Publikováno v:
Analytical Chemistry. 90:10009-10015
Mass spectrometry imaging (MSI) is a crucial label-free method to distinguish the localization patterns in single cells. MALDI-TOF MS and ToF-SIMS are now bearing the responsibility. However, MALDI-TOF MS is limited to micron spatial resolution and T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::773052185817269d97ff8d064c3ad813
https://doi.org/10.1021/acs.analchem.8b02478
https://doi.org/10.1021/acs.analchem.8b02478