Escalated complement activation during hospitalization is associated with higher risk of 60-day mortality in SARS-CoV-2-infected patients.

Autor: Barratt-Due A; Department of Anesthesia and Intensive Care Medicine, Oslo University Hospital, Oslo, Norway., Pettersen K; Research Laboratory, Nordland Hospital Trust, Bodø, Norway., Børresdatter-Dahl T; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway., Holter JC; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Grønli RH; Research Laboratory, Nordland Hospital Trust, Bodø, Norway., Dyrhol-Riise AM; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway., Lerum TV; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway., Holten AR; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Acute Medicine, Oslo University Hospital, Oslo, Norway., Tonby K; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway., Trøseid M; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, University of Oslo, Oslo, Norway., Skjønsberg OH; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway., Granerud BK; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Heggelund L; Department of Internal Medicine, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.; Department of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway., Kildal AB; Department of Anesthesiology and Intensive Care, University Hospital of North Norway, Tromsø, Norway.; Department of Clinical Medicine, Faculty of Health Sciences, UIT-The Arctic University of Norway, Tromsø, Norway., Schjalm C; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Immunology, Oslo University Hospital, Oslo, Norway., Aaløkken TM; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway., Aukrust P; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, University of Oslo, Oslo, Norway., Ueland T; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway., Mollnes TE; Research Laboratory, Nordland Hospital Trust, Bodø, Norway.; Department of Immunology, Oslo University Hospital, Oslo, Norway., Halvorsen B; Research Institute for Internal Medicine, Oslo University Hospital, Oslo, Norway.; Insitute of Clinical Medicine, University of Oslo, Oslo, Norway.

Publikováno v: Journal of internal medicine [J Intern Med] 2024 Jul; Vol. 296 (1), pp. 80-92. Date of Electronic Publication: 2024 Mar 27.

Trajectory of cardiac troponin T following moderate-to-severe COVID-19 and the association with cardiac abnormalities.

Autor: Øvrebotten T; Department of Cardiology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway.; K.G. Jebsen Center for Cardiac Biomarkers, Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Mecinaj A; Department of Cardiology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway.; K.G. Jebsen Center for Cardiac Biomarkers, Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Stavem K; Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway.; Department of Pulmonary Medicine, Akershus University Hospital, Lørenskog, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Ghanima W; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Hemato-oncology, Østfold Hospital Kalnes, Østfold, Norway., Brønstad E; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.; Thoracic Department, St. Olavs Hospital, Trondheim, Norway., Durheim MT; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Department of Respiratory Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Lerum TV; Department of Pulmonary Medicine, Oslo University Hospital Ullevål, Oslo, Norway., Josefsen T; Department of Cardiology, Østfold Hospital Kalnes, Østfold, Norway., Grimsmo J; Department of cardiac and pulmonary rehabilitation, Cathinka Guldberg's Hospital, Lovisenberg Rehabilitation, Jessheim, Norway., Heck SL; K.G. Jebsen Center for Cardiac Biomarkers, Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Diagnostic Imaging, Akershus University Hospital, Lørenskog, Norway., Omland T; Department of Cardiology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway.; K.G. Jebsen Center for Cardiac Biomarkers, Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Ingul CB; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway., Einvik G; Department of Pulmonary Medicine, Akershus University Hospital, Lørenskog, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Myhre PL; Department of Cardiology, Division of Medicine, Akershus University Hospital, Lørenskog, Norway. p.l.myhre@medisin.uio.no.; K.G. Jebsen Center for Cardiac Biomarkers, Institute for Clinical Medicine, University of Oslo, Oslo, Norway. p.l.myhre@medisin.uio.no.

Publikováno v: BMC cardiovascular disorders [BMC Cardiovasc Disord] 2024 Apr 13; Vol. 24 (1), pp. 206. Date of Electronic Publication: 2024 Apr 13.

A prospective study of pulmonary outcomes and chest computed tomography in the first year after COVID-19.

Autor: Lerum TV; Department of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Meltzer C; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway., Rodriguez JR; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway., Aaløkken TM; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital, Oslo, Norway., Brønstad E; Thoracic Department, St Olav's Hospital, Trondheim, Norway.; Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, NTNU, Trondheim, Norway., Aarli BB; Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Science, University of Bergen, Bergen, Norway., Aarberg-Lund KM; Department of Infectious Diseases, Østfold Hospital Trust Kalnes, Grålum, Norway., Durheim MT; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Respiratory Medicine, Oslo University Hospital, Oslo, Norway., Ashraf H; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Diagnostic Imaging, Akershus University Hospital, Lørenskog, Norway., Einvik G; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Pulmonary Department, Akershus University Hospital, Lørenskog, Norway., Skjønsberg OH; Department of Pulmonary Medicine, Oslo University Hospital, Oslo, Norway.; Institute for Clinical Medicine, University of Oslo, Oslo, Norway., Stavem K; Institute for Clinical Medicine, University of Oslo, Oslo, Norway.; Pulmonary Department, Akershus University Hospital, Lørenskog, Norway.; Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway.

Publikováno v: ERJ open research [ERJ Open Res] 2023 Mar 13; Vol. 9 (2). Date of Electronic Publication: 2023 Mar 13 (Print Publication: 2023).

High Circulating Levels of the Homeostatic Chemokines CCL19 and CCL21 Predict Mortality and Disease Severity in COVID-19.

Autor: Tveita A; Department of Internal Medicine, Bærum Hospital, Vestre Viken Hospital Trust, Gjettum, Norway.; Division of Laboratory Medicine, Department of Immunology, Oslo University Hospital, Oslo, Norway., Murphy SL; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Holter JC; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Kildal AB; Department of Anesthesiology and Intensive Care, University Hospital of North Norway, Tromsø, Norway., Michelsen AE; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Lerum TV; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pulmonary Medicine, Oslo University Hospital Ullevål, Oslo, Norway., Kaarbø M; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Heggelund L; Department of Internal Medicine, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.; Department of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway., Holten AR; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Acute Medicine, Oslo University Hospital, Oslo, Norway., Finbråten AK; Department of Medicine, Lovisenberg Diaconal Hospital, Oslo, Norway., Müller KE; Department of Internal Medicine, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway., Mathiessen A; Department of Medicine, Diakonhjemmet Hospital, Oslo, Norway., Bøe S; Department of Anesthesiology and Intensive Care, Hammerfest County Hospital, Hammerfest, Norway., Fevang B; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Oslo, Norway., Granerud BK; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Tonby K; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital Ullevål, Oslo, Norway., Lind A; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Dudman SG; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Henriksen KN; Department of Hematology, Oslo University Hospital, Oslo, Norway.; Hospital Pharmacies, South-Eastern Norway Enterprise, Oslo, Norway., Müller F; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Skjønsberg OH; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pulmonary Medicine, Oslo University Hospital Ullevål, Oslo, Norway., Trøseid M; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Oslo, Norway., Barratt-Due A; Division of Laboratory Medicine, Department of Immunology, Oslo University Hospital, Oslo, Norway.; Department of Anesthesia and Intensive Care Medicine, Oslo University Hospital, Oslo, Norway., Dyrhol-Riise AM; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital Ullevål, Oslo, Norway., Aukrust P; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital, Oslo, Norway., Halvorsen B; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Dahl TB; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Department of Acute Medicine, Oslo University Hospital, Oslo, Norway., Ueland T; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Research Institute of Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Department of Clinical Medicine, Thrombosis Research and Expertise Center, Arctic University of Norway, Tromsø, Norway.

Publikováno v: The Journal of infectious diseases [J Infect Dis] 2022 Dec 13; Vol. 226 (12), pp. 2150-2160.

Persistent T-cell exhaustion in relation to prolonged pulmonary pathology and death after severe COVID-19: Results from two Norwegian cohort studies.

Autor: Trøseid M; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Dahl TB; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Division of Critical Care and Emergencies, Oslo University Hospital, Oslo, Norway., Holter JC; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Kildal AB; Department of Anesthesiology and Intensive Care, University Hospital of North Norway, Tromsø, Norway., Murphy SL; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Yang K; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Quiles-Jiménez A; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Heggelund L; Department of Internal Medicine, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.; Department of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway., Müller KE; Department of Internal Medicine, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway., Tveita A; Department of Internal Medicine, Baerum Hospital, Vestre Viken Hospital Trust, Gjettum, Norway.; Division of Laboratory Medicine, Department of Immunology, Oslo University Hospital, Oslo, Norway., Michelsen AE; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Bøe S; Department of Anesthesiology and Intensive Care, Hammerfest County Hospital, Hammerfest, Norway., Holten AR; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Acute Medicine, Oslo University Hospital, Oslo, Norway., Hoel H; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Department of Internal Medicine, Lovisenberg Diakonal Hospital, Oslo, Norway., Mathiessen A; Department of Internal Medicine, Diakonhjemmet Hospital, Oslo, Norway., Aaløkken TM; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Radiology and Nuclear Medicine, Oslo University Hospital Ullevål, Oslo, Norway., Fevang B; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, Oslo, Norway., Granerud BK; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Tonby K; Department of Infectious Diseases, Oslo University Hospital Ullevål, Oslo, Norway., Henriksen KN; Hospital Pharmacies, South-Eastern Norway Enterprise, Oslo, Norway.; Department of Hematology, Oslo University Hospital Rikshospitalet, Oslo, Norway., Lerum TV; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pulmonary Medicine, Oslo University Hospital Ullevål, Oslo, Norway., Müller F; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Skjønsberg OH; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Pulmonary Medicine, Oslo University Hospital Ullevål, Oslo, Norway., Barratt-Due A; Division of Critical Care and Emergencies, Oslo University Hospital, Oslo, Norway.; Division of Laboratory Medicine, Department of Immunology, Oslo University Hospital, Oslo, Norway., Dyrhol-Riise AM; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious Diseases, Oslo University Hospital Ullevål, Oslo, Norway., Aukrust P; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Section of Clinical Immunology and Infectious Diseases, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Halvorsen B; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Ueland T; Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Clinical Medicine, Thrombosis Research and Expertise Center (TREC), UiT-The Arctic University of Norway, Tromsø, Norway.

Publikováno v: Journal of internal medicine [J Intern Med] 2022 Nov; Vol. 292 (5), pp. 816-828. Date of Electronic Publication: 2022 Aug 18.