Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Leroy W Wheeler"'
Autor:
Yingjuan J. Lu, Leroy W. Wheeler, II, Haiyan Chu, Paul J. Kleindl, Michael Pugh, Fei You, Satish Rao, Gabriela Garcia, Henry Y. Wu, Andre P. da Cunha, Richard Johnson, Elaine Westrick, Vicky Cross, Alex Lloyd, Christina Dircksen, Patrick J. Klein, Iontcho R. Vlahov, Philip S. Low, Christopher P. Leamon
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100422- (2021)
Summary: Provoked by sterile/nonsterile insults, prolonged monocyte mobilization and uncontrolled monocyte/macrophage activation can pose imminent or impending harm to the affected organs. Curiously, folate receptor beta (FRβ), with subnanomolar aff
Externí odkaz:
https://doaj.org/article/e2fda03da1f14baea081c09735a4dc68
Autor:
Yingjuan J. Lu, Haiyan Chu, Leroy W. Wheeler, Melissa Nelson, Elaine Westrick, James F. Matthaei, Ian I. Cardle, Adam Johnson, Joshua Gustafson, Nikki Parker, Marilynn Vetzel, Le-Cun Xu, Emilia Z. Wang, Michael C. Jensen, Patrick J. Klein, Philip S. Low, Christopher P. Leamon
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Chimeric antigen receptor (CAR)-T cell therapy has transformed pediatric oncology by producing high remission rates and potent effects in CD19+ B-cell malignancies. This scenario is ideal as CD19 expression is homogeneous and human blood provides a f
Externí odkaz:
https://doaj.org/article/25853ddcfde5498d880a46edf8747200
Autor:
Philip S. Low, Paul J. Kleindl, Andre P. da Cunha, Satish Rao, Patrick J. Klein, Leroy W Wheeler, Henry Y. Wu, Christopher P. Leamon, Yingjuan J. Lu, Fei You, Alex Lloyd, Christina Dircksen, Chu Haiyan, Michael Pugh, Gabriela E. Garcia, Vicky Cross, Elaine Westrick, Richard J. Johnson, Iontcho R. Vlahov
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 10, Pp 100422-(2021)
Cell Reports Medicine
Cell Reports Medicine
Summary Provoked by sterile/nonsterile insults, prolonged monocyte mobilization and uncontrolled monocyte/macrophage activation can pose imminent or impending harm to the affected organs. Curiously, folate receptor beta (FRβ), with subnanomolar affi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff3f0adb683c62473135f1023e5e206
http://www.sciencedirect.com/science/article/pii/S2666379121002846
http://www.sciencedirect.com/science/article/pii/S2666379121002846
Autor:
Rodney D. Newberry, Keely G. McDonald, Leroy W. Wheeler, Jeremiah R. McDole, Kathryn A. Knoop, Devesha H. Kulkarni, Jenny K. Gustafsson, Mark J. Miller, Ifor R. Williams, Shannon Joerger
Publikováno v:
Immunology. 152:613-627
The intestinal lamina propria (LP) contains antigen‐presenting cells with features of dendritic cells and macrophages, collectively referred to as mononuclear phagocytes (MNPs). Association of MNPs with the epithelium is thought to play an importan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a88acc93f453580e98e73c850494c2d
https://doi.org/10.1111/imm.12801
https://doi.org/10.1111/imm.12801
Autor:
Joshua A. Gustafson, Adam Johnson, Patrick J. Klein, Christopher P. Leamon, Ian I. Cardle, Philip S. Low, Melissa Nelson, Nikki Parker, Yingjuan J. Lu, Marilynn Vetzel, Le-Cun Xu, Matthaei James, Elaine Westrick, Leroy W. Wheeler, Emilia Z. Wang, Haiyan Chu, Michael C. Jensen
Publikováno v:
Frontiers in Oncology
Frontiers in Oncology, Vol 9 (2019)
Frontiers in Oncology, Vol 9 (2019)
Chimeric antigen receptor (CAR)-T cell therapy has transformed pediatric oncology by producing high remission rates and potent effects in CD19+ B-cell malignancies. This scenario is ideal as CD19 expression is homogeneous and human blood provides a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f550c5fe33194fd6fcc376e550b8cce
https://doi.org/10.3389/fonc.2019.00151
https://doi.org/10.3389/fonc.2019.00151
Autor:
Elaine Westrick, Iontcho Radoslavov Vlahov, Le-Cun Xu, Leroy W. Wheeler, Yingjuan Lu, Jeremy F. Vaughn, Christopher P. Leamon, Torian W. Stinnette, Kristin N. Wollak, Vicky A. Cross, Spencer Hahn
Publikováno v:
Clinical Immunology. 150:64-77
EC0746 is a rationally designed anti-inflammatory drug conjugate consisting of a modified folic acid-based ligand linked to a γ-hydrazide analog of aminopterin. In this report, EC0746's effectiveness was evaluated against experimental retinal S-anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d65766fdd1fc20cb502c81979eb0016
https://doi.org/10.1016/j.clim.2013.10.010
https://doi.org/10.1016/j.clim.2013.10.010
Autor:
Jeremiah R. McDole, Kathryn A. Knoop, Baomei Wang, Mark J. Miller, Keely G. McDonald, Rodney D. Newberry, Vjollca Konjufca, Leroy W. Wheeler
Publikováno v:
Nature
The intestinal immune system is exposed to a mixture of foreign antigens from diet, commensal flora and potential pathogens. Understanding how pathogen-specific immunity is elicited while avoiding inappropriate responses to the background of innocuou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d74c3e77d3b11a480ca5c675c5230292
https://doi.org/10.1038/nature10863
https://doi.org/10.1038/nature10863
Functional folate receptor cells within synovium and fluid as therapeutic targets for osteoarthritis
Autor:
Virginia B. Kraus, M.-F. Hsueh, Y. Lu, Michael P. Bolognesi, Samuel S. Wellman, Leroy W. Wheeler
Publikováno v:
Osteoarthritis and Cartilage. 25:S42-S43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1d28cc286c5b90879c75625adb2ae1b
https://doi.org/10.1016/j.joca.2017.02.082
https://doi.org/10.1016/j.joca.2017.02.082
Autor:
Manreet Kaur, Rodney D. Newberry, Elyse K. Hanly, Leroy W. Wheeler, Caihong Wang, Keely G. McDonald
Publikováno v:
Inflammatory Bowel Diseases. 16:1751-1762
Integrins are dimeric cell surface molecules composed of α and β subunits that promote cell–cell interactions and play important roles in the immune system. Within the integrin family, α4β7 displays relative specificity for the mucosal immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4617c4bafc9b527de4d43f7a723a5a09
https://doi.org/10.1002/ibd.21266
https://doi.org/10.1002/ibd.21266
Autor:
Marilynn Vetzel, Christopher P. Leamon, Haiyan Chu, Mellissa Nelson, Yong Gu Lee, Leroy W. Wheeler, Elaine Westrick, Yingjuan Lu, Patrick J. Klein, Philip S. Low
Publikováno v:
Cancer Research. 78:2546-2546
Chimeric antigen receptor modified T cell (CAR-T) therapy has revolutionized personalized cancer treatment. The recent FDA approval of two CAR-T therapies for hematological cancers has marked a pivotal milestone in this new era of cellular therapies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72435d21658b2dbca20d70b093492d09
https://doi.org/10.1158/1538-7445.am2018-2546
https://doi.org/10.1158/1538-7445.am2018-2546