Zobrazeno 1 - 10
of 2 404
pro vyhledávání: '"Leroy L"'
Autor:
Gary F. Mitchell, Jian Rong, Martin G. Larson, Leroy L. Cooper, Vanessa Xanthakis, Emelia J. Benjamin, Naomi M. Hamburg, Ramachandran S. Vasan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 12 (2023)
Background Systolic blood pressure increases with age after midlife, particularly in women, and contributes to development of wide pulse pressure hypertension in middle‐aged and older adults. Relative contributions of aortic stiffness and premature
Externí odkaz:
https://doaj.org/article/54fe6dd335ef43b8b2476a61e7d7073d
Autor:
Leroy L. Cooper, Jian Rong, Pauline Maillard, Alexa Beiser, Naomi M. Hamburg, Martin G. Larson, Charles DeCarli, Ramachandran S. Vasan, Sudha Seshadri, Gary F. Mitchell
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundDysregulation of compensatory mechanisms to regulate blood pressure (BP) upon postural change is a phenotype of BP variability and an emerging risk factor for cardiovascular outcomes.Materials and methodsWe assessed postural change in BP (s
Externí odkaz:
https://doaj.org/article/604247e7eb5b48738e733059bbf95a7f
Autor:
Harsha S. Nagarajarao, Solomon K. Musani, Keith E. Cobb, James D. Pollard, Leroy L. Cooper, Anshul Anugu, Yuichiro Yano, Josiah A. Moore, Connie W. Tsao, Albert W. Dreisbach, Emelia J. Benjamin, Naomi M. Hamburg, Ramachandran S. Vasan, Gary F. Mitchell, Ervin R. Fox
Publikováno v:
Kidney Medicine, Vol 3, Iss 5, Pp 702-711.e1 (2021)
Rationale & Objective: The relation of vascular stiffness, endothelial function, and kidney function is incompletely elucidated in African Americans. Our hypothesis was that increased vascular stiffness and endothelial dysfunction are associated with
Externí odkaz:
https://doaj.org/article/3cca258a02bc4439ab5a7aab2f19e77e
Autor:
Leroy L. Cooper, Solomon K. Musani, Josiah A. Moore, Victoria A. Clarke, Yuichiro Yano, Keith Cobbs, Connie W. Tsao, Javed Butler, Michael E. Hall, Naomi M. Hamburg, Emelia J. Benjamin, Ramachandran S. Vasan, Gary F. Mitchell, Ervin R. Fox
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 18 (2020)
Background Measures of vascular dysfunction are related to adverse cardiovascular disease (CVD) outcomes in non‐Hispanic, White populations; however, data from Black individuals are limited. We aimed to investigate the associations between novel he
Externí odkaz:
https://doaj.org/article/b673583a15d54eaa9ef544b01030bbdc
Enhancing Autophagy Diminishes Aberrant Ca2+ Homeostasis and Arrhythmogenesis in Aging Rabbit Hearts
Autor:
Kevin R. Murphy, Brett Baggett, Leroy L. Cooper, Yichun Lu, Jin O-Uchi, John M. Sedivy, Dmitry Terentyev, Gideon Koren
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
AimAging in humans is associated with a 10–40-fold greater incidence of sudden cardiac death from malignant tachyarrhythmia. We have reported that thiol oxidation of ryanodine receptors (RyR2s) by mitochondria-derived reactive oxygen species (mito-
Externí odkaz:
https://doaj.org/article/28f8dbb9fc3242e4974f494ea275273f
Autor:
Connie W. Tsao, Floyd Washington, Solomon K. Musani, Leroy L. Cooper, Avnish Tripathi, Naomi M. Hamburg, Emelia J. Benjamin, Ramachandran S. Vasan, Gary F. Mitchell, Ervin R. Fox
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 21 (2018)
Background Black individuals have greater risk for cardiovascular disease (CVD) than whites. Identifying CVD risk factors associated with abnormal aortic hemodynamics in blacks may optimize CVD prevention and treatment strategies. Methods and Results
Externí odkaz:
https://doaj.org/article/39bfbc86b3c24c4890c0d1908053e217
Autor:
Leroy L. Cooper, Solomon K. Musani, Floyd Washington, Jonathan Moore, Avnish Tripathi, Connie W. Tsao, Naomi M. Hamburg, Emelia J. Benjamin, Ramachandran S. Vasan, Gary F. Mitchell, Ervin R. Fox
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 20 (2018)
Background Blacks have more severe endothelial dysfunction and aortic stiffening as compared with whites. We aimed to investigate the association between aortic stiffness and microvascular function in the black community. Methods and Results We asses
Externí odkaz:
https://doaj.org/article/27adaf3b91d64373911b38603231fed9
Autor:
Matthew Nayor, Leroy L. Cooper, Danielle M. Enserro, Vanessa Xanthakis, Martin G. Larson, Emelia J. Benjamin, Jayashri Aragam, Gary F. Mitchell, Ramachandran S. Vasan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 11 (2018)
BackgroundLeft ventricular diastolic dysfunction (DD) is common, particularly in women and older individuals, and it is associated with adverse cardiovascular outcomes. We evaluated the impact of age‐ and sex‐specific diagnostic criteria on the a
Externí odkaz:
https://doaj.org/article/4386fae6104a4f1dbce49db51452f58f
Autor:
Leroy L. Cooper, Jayandra J. Himali, Alyssa Torjesen, Connie W. Tsao, Alexa Beiser, Naomi M. Hamburg, Charles DeCarli, Ramachandran S. Vasan, Sudha Seshadri, Matthew P. Pase, Gary F. Mitchell
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 8 (2017)
BackgroundRelations of orthostatic change in blood pressure with brain structure and function have not been studied thoroughly, particularly in younger, healthier individuals. Elucidation of factors that contribute to early changes in brain integrity
Externí odkaz:
https://doaj.org/article/592439608d1d4e2484cff488c923386a