Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Leroy J. Honkomp"'
Publikováno v:
Gastroenterology. 69:636-640
Pepto-Bismol liquid (primary active constituent, bismuth subsalicy-late) protected the gastric mucosa of rats against the formation of hemorrhagic lesions or erosions in response to cold + restraint stress, to a combination of aspirin and cold + rest
Publikováno v:
Pharmacological Research Communications. 10:13-20
Summary A series of experiments was conducted to determine the efficacy of bismuth subsalicylate slurry in protecting the rat stomach from hemorrhagic lesion or erosion formation resulting from various noxious stimuli. Bismuth subsalicylate slurry (8
Publikováno v:
The American Journal of Digestive Diseases. 20:955-960
The antidiarrheal effectiveness of bismuth subsalicylate was determined in two species of laboratory animals. Doses of castor oil were, at first, found to accelerate significantly the movement of a charcoal test meal along the small intestine of the
Publikováno v:
Journal of Pharmaceutical Sciences. 62:948-951
Dantrolene causes skeletal muscle relaxation in animals without prominent CNS actions, and it has little or no measurable effect on smooth or cardiac muscle. Dantrolene reduces rigidity in decerebrate cats. Unlike centrally acting muscle relaxants, i
Publikováno v:
Journal of Pharmacy and Pharmacology. 17:222-226
Fenfluramine hydrochloride (N-ethyl-α-methyl-3-trifluoromethylphenethylamine hydrochloride; AHR-965) administered orally or intravenously to anaesthetised or unanaesthetised dogs, caused a predominant rise in arterial blood pressure, tachycardia, an
Publikováno v:
Journal of Pharmaceutical Sciences. 67:1022-1024
The synthesis and hypotensive activity in the dog of a series of 2-substituted 5,6-dimethoxyindazoles are reported. Structure-activity relationships for this class of compounds are discussed. Indazoles containing the diethylaminoethyl, 3-pyridyl, and
Publikováno v:
Chemischer Informationsdienst. 9
The synthesis and hypotensive activity in the dog of a series of 2-substituted 5,6-dimethoxyindazoles are reported. Structure-activity relationships for this class of compounds are discussed. Indazoles containing the diethylaminoethyl, 3-pyridyl, and
Publikováno v:
Chemischer Informationsdienst. 9
Publikováno v:
Journal of pharmaceutical sciences. 65(9)
Laboratory and clinical investigations were carried out to determine the effectiveness of bismuth subsalicylate in allaying nausea by preventing the physical symptom of emesis. In normal conscious dogs, a bismuth subsalicylate formulation caused a do