Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Leroi V. DeSouza"'
Supplementary Figure Legend from Small Interfering RNA Targeting 14-3-3ζ Increases Efficacy of Chemotherapeutic Agents in Head and Neck Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5238198d7640610b6087e09e17d071c0
https://doi.org/10.1158/1535-7163.22485818.v1
https://doi.org/10.1158/1535-7163.22485818.v1
Patients diagnosed in advanced stages of head and neck squamous cell carcinoma often show limited response to chemotherapeutic agents. Recently, we reported the overexpression of 14-3-3ζ protein in head and neck premalignant and cancer tissues using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75bb84459f2572078b807a137904516
https://doi.org/10.1158/1535-7163.c.6532094.v1
https://doi.org/10.1158/1535-7163.c.6532094.v1
Supplementary Figure from Small Interfering RNA Targeting 14-3-3ζ Increases Efficacy of Chemotherapeutic Agents in Head and Neck Cancer Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8967816cb457f1fcd3de49bb384eda94
https://doi.org/10.1158/1535-7163.22485815.v1
https://doi.org/10.1158/1535-7163.22485815.v1
Autor:
Sébastien N Voisin, Olga Krakovska, Ajay Matta, Leroi V DeSouza, Alexander D Romaschin, Terence J Colgan, K W Michael Siu
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16352 (2011)
BACKGROUND: The number of patients with endometrial carcinoma (EmCa) with advanced stage or high histological grade is increasing and prognosis has not improved for over the last decade. There is an urgent need for the discovery of novel molecular ta
Externí odkaz:
https://doaj.org/article/99f6a49d74ff48f182be9fd63b684b09
Autor:
K. W. Michael Siu, Leroi V. DeSouza
Publikováno v:
Clinical Biochemistry. 46:421-431
Objective This review describes the most common methods currently used for mass spectrometry‐based quantification in proteomic applications. Design and methods Quantification can be performed using either labeled or unlabeled approaches. Labeled ap
Autor:
Robert Stewart, Olena Masui, Bishoy Khalil, Kenneth T. Pace, Leroi V. DeSouza, Olga Krakovska, Shereen Metias, George M. Yousef, Alexander D. Romaschin, Ajay Matta, K. W. Michael Siu, Georg A. Bjarnason, R. John D'a. Honey, Nicole M.A. White
Publikováno v:
Molecular & Cellular Proteomics. 12:132-144
Metastatic renal cell carcinoma (RCC) is one of the most treatment-resistant malignancies, and patients have a dismal prognosis, with a
Autor:
Cynthia Hawkins, Ayako Ochi, Lili-Naz Hazrati, Simon X. Wang, Bette K. Kleinschmidt-DeMasters, K. W. Michael Siu, Blair Cappel, Shelly K. Weiss, James T. Rutka, Michael H. Handler, Cristina Go, Hiroshi Otsubo, Harry V. Vinters, Leroi V. DeSouza, Naomi P. Visanji, Janice C. Wong
Publikováno v:
Epilepsia. 53:e50-e54
Summary Cerebral hyaline astrocytic inclusions have been observed in a subset of patients with early onset epilepsy, brain structural anomalies, and developmental delay, which indicates that it may represent a unique clinicopathologic entity. To furt
Autor:
Imogen R. Coe, Nicole M.I. Nivillac, K. W. Michael Siu, Leroi V. DeSouza, Muhammad Zia Karim, German Reyes
Publikováno v:
Molecular Membrane Biology. 28:412-426
Equilibrative Nucleoside Transporters (SLC29) are a family of proteins that transport nucleosides, nucleobases and nucleoside analogue drugs across cellular membranes. ENT1 is expressed ubiquitously in mammalian tissues and responsible for a signific
Publikováno v:
Mass Spectrometry Reviews. 29:945-961
Mass spectrometry (MS)-based proteomics is a rapidly developing technology for both qualitative and quantitative analyses of proteins, and investigations into protein posttranslational modifications, subcellular localization, and interactions. Recent
Publikováno v:
Analytical Chemistry. 81:3462-3470
Multidimensional liquid chromatography with tandem mass spectrometry with iTRAQ-labeling typically used for differential expression analysis in biomarker discovery does not always detect peptides from these biomarkers in all samples analyzed. Herein