Výsledky vyhledávání - "Lerner B. Hinshaw"

PERITONITIS IN THE BABOON: A PRIMATE MODEL WHICH SIMULATES HUMAN SEPSIS

Autor: Gary T. Kinasewitz, Fletcher B. Taylor, G. Peer, Lerner B. Hinshaw, Alvin C. K. Chang

Publikováno v: Shock. 13:100-109

The physiological, hemostatic, and immunological responses of 12 chronically instrumented conscious baboons with sepsis due to Escherichia coli peritonitis were compared with that of similarly instrumented controls. Chronic indwelling cannulae were p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b849b9476226a02a12dd34cdb108aa9e
https://doi.org/10.1097/00024382-200013020-00003

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Sepsis/septic shock

Autor: Lerner B. Hinshaw

Publikováno v: Critical Care Medicine. 24:1072-1078

Objective An overview of the importance of understanding mechanisms occurring in the microcirculation during septic and endotoxic shock. The thesis of the paper is to place emphasis on this important vascular network to ultimately benefit the patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d9865addc5ac7807a5365fdfd4ab90fe
https://doi.org/10.1097/00003246-199606000-00031

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Group A Streptococcal Bacteremia: The Role of Tumor Necrosis Factor in Shock and Organ Failure

Autor: Sean P. Hackett, Stanley D. Kosanke, Amy E. Bryant, Dennis L. Stevens, T. Emerson, Chang Ak, Lerner B. Hinshaw, G. Peer

Publikováno v: Journal of Infectious Diseases. 173:619-626

Severe group A streptococcal infections associated with early onset shock and multiorgan failure define the streptococcal toxic shock syndrome. In the United States, group A streptococcal strains most commonly isolated are M types 1 and 3, which prod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8420c7afafa4954436875c38f9447d
https://doi.org/10.1093/infdis/173.3.619

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Continuous arteriovenous hemofiltration therapy for Staphylococcus aureus-induced septicemia in immature swine

Autor: James R. Matson, Lerner B. Hinshaw, Robert W. Pryor, Patrice A. Lee

Publikováno v: Critical Care Medicine. 21:914-924

Objectives. The goals of this study were: a) to evaluate the efficacy of controlled, continuous arteriovenous hemofiltration in improving morbidity and mortality rates in an immature swine model of Staphylococcus aureus-induced septicemia; b) to dete

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5be2505de0857090eaae01b41f484fa
https://doi.org/10.1097/00003246-199306000-00022

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LETHAL STAPHYLOCOCCUS AUREUS-INDUCED SHOCK IN PRIMATES

Autor: Dale J. Flournoy, Michael A. Fournel, Richard B. Passey, Alvin C. K. Chang, Fletcher B. Taylor, G. Peer, Cynthia K. Murray, Melinda Duerr, Stanley D. Kosanke, Lerner B. Hinshaw, Thomas E. Emerson, Gary L. White, Robert Xu

Publikováno v: The Journal of Trauma: Injury, Infection, and Critical Care. 33:568-573

A successful experimental treatment for gram-positive sepsis to our knowledge has not been achieved. The objectives of this study were to develop a nonhuman primate model of lethal gram-positive sepsis employing the micro-organism Staphytococcus aure

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f18742a67dbd1a5dbeae02a7a835dff3
https://doi.org/10.1097/00005373-199210000-00013

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Impact of encephalopathy on mortality in the sepsis syndrome

Autor: Charles L. Sprung, Clayton H. Shatney, Roland M. H. Schein, Michael F. Wilson, John N. Sheagren, Peter Peduzzi, Lerner B. Hinshaw

Publikováno v: Critical Care Medicine. 18:801-806

Sepsis, an important cause of hospital mortality, continues to be a diagnostic and therapeutic challenge. To define more clearly the impact of encephalopathy on the course of sepsis, the various clinical signs of sepsis, blood culture results, and mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6b9b2705638957e2e9b3876bc03070fe
https://doi.org/10.1097/00003246-199008000-00001

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Comparison of the capacity of rhTNF-alpha and Escherichia coli to induce procoagulant activity by baboon mononuclear cells in vivo and in vitro

Autor: Alvin C. K. Chang, Anguo Li, Lerner B. Hinshaw, G. Peer, Fletcher B. Taylor

Publikováno v: Shock (Augusta, Ga.). 5(4)

The procoagulant activity of mononuclear cells (MNCs) may play an important role in the disseminated intravascular coagulation seen in septic shock. This study compares the capacity of Escherichia coli (E. coli) and recombinant human TNF-alpha (rhTNF

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94eabb9814236e933d7eff3e734ef6fc
https://pubmed.ncbi.nlm.nih.gov/8721387

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Preclinical review of anti-tumor necrosis factor monoclonal antibodies

Autor: Michael A. Fournel, Lerner B. Hinshaw, Mark Bodmer

Publikováno v: Critical care medicine. 21

Objective To review the preclinical evidence for the role of tumor necrosis factor (TNF) in the pathogenesis of septic shock and to assess the preclinical efficacy of anti-TNF therapies for this clinical problem. Data sources The international Englis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ef0c45e9c2c0ed75ddf485af0c13a4
https://pubmed.ncbi.nlm.nih.gov/8403982

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