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Akademický článek

Autor: van Saene, J. J. M., van Saene, H. K. F., Lerk, C. F.

Publikováno v: The Journal of Infectious Diseases, 1986 May 01. 153(5), 999-1000.

Externí odkaz: https://www.jstor.org/stable/30105037

THE USE OF A FACTORIAL DESIGN TO EVALUATE THE PHYSICAL STABILITY OF TABLETS PREPARED BY DIRECT COMPRESSION .2. SELECTION OF EXCIPIENTS SUITABLE FOR USE UNDER TROPICAL STORAGE-CONDITIONS

Autor: Bos, C. E., BOLHUIS, G. K., LERK, C. F., de Boer, J. H., DUINEVELD, C. A. A., Smilde, A. K., Doornbos, D. A.

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics, 37(4), 210-215. ELSEVIER SCIENCE BV
European journal of pharmaceutics and biopharmaceutics, 37(4), 210-215. Elsevier

A factorial design has been used to study the influence of disintegrant concentration, storage temperature and relative humidity upon storage on the physical stability of tablets prepared by direct compression. Tablets prepared from a binary mixture

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ad80ecb78eb92d62de06f766102d4383
https://research.rug.nl/en/publications/022c6530-0775-42e1-bc35-0ef2b6815eda

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THE USE OF A FACTORIAL DESIGN TO EVALUATE THE PHYSICAL STABILITY OF TABLETS PREPARED BY DIRECT COMPRESSION .1. A NEW APPROACH BASED ON THE RELATIVE CHANGE IN TABLET PARAMETERS

Autor: Bos, C. E., BOLHUIS, G. K., LERK, C. F., de Boer, J. H., DUINEVELD, C. A. A., Smilde, A. K., Doornbos, D. A.

Publikováno v: European Journal of Pharmaceutics and Biopharmaceutics, 37(4), 204-209. ELSEVIER SCIENCE BV
European journal of pharmaceutics and biopharmaceutics, 37(4), 204-209. Elsevier

A factorial design has been used to study the influence of disintegrant concentration and compression force as well as storage temperature and relative humidity on the physical stability during storage of alpha-lactose monohydrate/rice starch tablets

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f1a73ee9ec38065ce6b5e47bc0d29328
https://research.rug.nl/en/publications/ebddd61b-9216-40d6-8caa-62ee33adf434

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The effects of cyclodextrins on the disposition of intravenously injected drugs in the rat

Autor: Frijlink, H W, Franssen, E J, Eissens, Anko, Oosting, Roelof, Lerk, C F, Meijer, D K

Publikováno v: Pharmaceutical Research, 8(3), 380-384. SPRINGER/PLENUM PUBLISHERS

Naproxen and flurbiprofen form complexes with hydroxypropyl-beta-cyclodextrin; with stability constants of 2207 and 12515 M-1, respectively. However, only small fractions of the drug remain complexed when the drug-cyclodextrin complex is added to pla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::af87a111738c49071d8d0c206aecefa1
https://research.rug.nl/en/publications/a78c2668-3b3b-408f-93aa-ea59705d0f3e

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The effect of parenterally administered cyclodextrins on cholesterol levels in the rat

Autor: Frijlink, H W, Eissens, Anko, Hefting, N R, Poelstra, Klaas, Lerk, C F, Meijer, D K F

Publikováno v: Pharmaceutical Research, 8(1), 9-16. SPRINGER/PLENUM PUBLISHERS

The inclusion complex formation of intravenously administered hydroxypropyl-beta-cyclodextrin and beta-cyclodextrin with endogenous lipids was studied. We tested the hypothesis that complex formation of endogenous cholesterol with cyclodextrins in th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::5fa5bb6c93bf77b7f2327b5f18904c71
https://research.rug.nl/en/publications/8094cc7a-4c15-47ff-adcb-6ad54eedf69a

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