Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Lequn Li"'
Autor:
Jiazhou Ye, Yan Lin, Zhiling Liao, Xing Gao, Cheng Lu, Lu Lu, Julu Huang, Xi Huang, Shilin Huang, Hongping Yu, Tao Bai, Jie Chen, Xiaobo Wang, Mingzhi Xie, Min Luo, Jinyan Zhang, Feixiang Wu, Guobin Wu, Liang Ma, Bangde Xiang, Lequn Li, Yongqiang Li, Xiaoling Luo, Rong Liang
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-18 (2024)
Abstract This study profiled global single cell-spatial-bulk transcriptome landscapes of hepatocellular carcinoma (HCC) ecosystem from six HCC cases and a non-carcinoma liver control donor. We discovered that intratumoral heterogeneity mainly derived
Externí odkaz:
https://doaj.org/article/b02614148b714a878a0006a476722f4f
Autor:
Zhihong Tang, Tao Bai, Tao Wei, Xiaobo Wang, Jie Chen, Jiazhou Ye, Shangqi Li, Meng Wei, Xingzhi Li, Youzhi Lin, Juan Tang, Lequn Li, Feixiang Wu
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Backgrounds To compare the efficacy and safety of transcatheter arterial chemoembolization (TACE) combined Lenvatinib plus Camrelizumab (TLC) in unresectable hepatocellular carcinoma (uHCC) with those of TACE alone . Methods A retrospective
Externí odkaz:
https://doaj.org/article/ff15c116dd12477cb5724d9bb60072a3
Autor:
Shaojie Hu, Kelin Meng, Tianlai Wang, Rirong Qu, Boyu Wang, Yu Xi, Taiyan Yu, Zhiwei Yuan, Zihao Cai, Yitao Tian, Chenxi Zeng, Xue Wang, Wenbin Zou, Xiangning Fu, Lequn Li
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract Background IL-15 plays a vital role in enhancing NK cell- and T-cell-mediated antitumor immune responses; however, the direct effect of IL-15 on tumor cells has not been fully elucidated. Herein, we investigated the effect of IL-15 on lung a
Externí odkaz:
https://doaj.org/article/5c979793c48a408aa2200abf6493c9e7
Publikováno v:
The Clinical Respiratory Journal, Vol 18, Iss 8, Pp n/a-n/a (2024)
ABSTRACT Background Bazedoxifene is a third‐generation selective estrogen receptor modulator that inhibits the IL6/IL6R/GP130 signaling pathway by inhibiting IL6‐induced homodimerization of GP130. Considering that the IL6/IL6R/GP130 signaling pat
Externí odkaz:
https://doaj.org/article/1a4d5cc3c765470cbf2aecb4d0e851ad
Publikováno v:
Autoimmunity, Vol 57, Iss 1 (2024)
AbstractThymoma is closely associated with myasthenia gravis (MG). However, due to the heterogeneity of thymoma and the intricate pathogenesis of MG, it remains unclear why some patients with thymoma develop MG and others do not. In this study, we co
Externí odkaz:
https://doaj.org/article/3b9493a3216847cbbed9192375592fd5
Publikováno v:
Asian Journal of Surgery, Vol 46, Iss 11, Pp 4863-4865 (2023)
Externí odkaz:
https://doaj.org/article/c50358208daf41db8ed4b4735046fcb1
Publikováno v:
BMC Surgery, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background The intent of this research was to generate and investigate the D-dimer to lymphocyte ratio (DLR) capacity to forecast the risk and prognosis of colorectal cancer liver metastases (CRCLM). Methods From January 2010 to December 201
Externí odkaz:
https://doaj.org/article/ab36e1234afc4a6394d853eba24255d4
Autor:
Xingzhi Li, Jie Chen, Xiaobo Wang, Tao Bai, Shaolong Lu, Tao Wei, Zhihong Tang, Chengwen Huang, Bin Zhang, Bowen Liu, Lequn Li, Feixiang Wu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
PurposeTo evaluate the outcomes and prognostic factors for patients using conversion therapy with lenvatinib combined with transcatheter arterial chemoembolization (TACE) plus programmed cell death protein-1 (PD-1) inhibitors (LTP) for initially unre
Externí odkaz:
https://doaj.org/article/ef3d8a7f44ef49aa9df0d8198ccebd86
Autor:
Hui Xiong, Yu Xi, Zhiwei Yuan, Boyu Wang, Shaojie Hu, Can Fang, Yixin Cai, Xiangning Fu, Lequn Li
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Stimulator of interferon genes (STING) pathway activation predicts the effectiveness of targeting the PD-1/PD-L1 axis in lung cancer. Active IFN-γ signaling is a common feature in tumors that respond to PD-1/PD-L1 blockade. The connection between IF
Externí odkaz:
https://doaj.org/article/7129a3b8a6a24344a12442ff18683b0c
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Tumor metastasis is still an insurmountable obstacle in tumor treatment. Lung cancer represents one of the most common malignancies with high morbidity worldwide. hnRNPA1 has been reported to be involved in the regulation of tumor metastasis, while i
Externí odkaz:
https://doaj.org/article/0de4f17d866e4e698ba14faa6f3e948c