Zobrazeno 1 - 10
of 912
pro vyhledávání: '"Leptomycin"'
Publikováno v:
Oncology Reviews, Vol 18 (2024)
Chromosome Region Maintenance 1 (CRM1), also known as Exportin 1 (XPO1), is a protein that is critical for transport of proteins and RNA to the cytoplasm through the nuclear pore complex. CRM1 inhibition with small molecule inhibitors is currently be
Externí odkaz:
https://doaj.org/article/e5bc8c6adb384b8b8cc22dcfd2c8e2cc
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Temperature is a vital environmental factor affecting organisms’ survival as they determine the mechanisms to tolerate rapid temperature changes. We demonstrate an experimental system for screening chemicals that affect cold tolerance in C
Externí odkaz:
https://doaj.org/article/fdab131b46394911a39206de15073505
Akademický článek
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Autor:
Chuanwen Lu1, Changxia Shao1, Cobos, Everardo2, Singh, Kamaleshwar P.1, Gao, Weimin1,2 weimin.gao@tiehh.ttu.edu
Publikováno v:
PLoS ONE. Mar2012, Vol. 7 Issue 3, p1-12. 12p.
Autor:
Aksu, Metin1, Pleiner, Tino1, Karaca, Samir2, Kappert, Christin1, Dehne, Heinz-Jürgen1, Seibel, Katharina1, Urlaub, Henning2,3, Bohnsack, Markus T.4, Görlich, Dirk1 goerlich@mpibpc.mpg.de
Publikováno v:
Journal of Cell Biology. Jul2018, Vol. 217 Issue 7, p2329-2340. 12p.
Autor:
Feliciano Monterrubio-Ledezma, Fernando Navarro-García, Lourdes Massieu, Ricardo Mondragón-Flores, Luz Adriana Soto-Ponce, Jonathan J. Magaña, Bulmaro Cisneros
Publikováno v:
Cells, Vol 12, Iss 2, p 275 (2023)
Hutchinson-Gilford progeria syndrome (HGPS) is a rare premature aging disorder caused by the expression of progerin, a mutant variant of Lamin A. Recently, HGPS studies have gained relevance because unraveling its underlying mechanism would help to u
Externí odkaz:
https://doaj.org/article/522ab2153bd04ec2928cf2b54562f744
Publikováno v:
Brain Research. Sep2017, Vol. 1670, p14-23. 10p.
Autor:
Rahmani, Khatera1, Dean, David A.1 david_dean@urmc.rochester.edu
Publikováno v:
Biochemical & Biophysical Research Communications. Jun2017, Vol. 488 Issue 2, p253-258. 6p.
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
We have identified triptolide as a novel NRF2 inhibitor, which significantly attenuates ARE-luciferase activity at nanomolar concentrations. Triptolide did not affect the level of NRF2, but significantly inhibited the expression of NRF2 target genes
Externí odkaz:
https://doaj.org/article/ab42e9d9e5b543aa84c8ff0835e89724
Autor:
Kim, Duk-Soo1, Min, Su-Ji2,3, Kim, Min-Ju2,3, Kim, Ji-Eun2,3, Kang, Tae-Cheon2,3 tckang@hallym.ac.kr
Publikováno v:
Brain Research. Nov2016, Vol. 1651, p27-35. 9p.