Zobrazeno 1 - 10
of 8 069
pro vyhledávání: '"Leppert A"'
Reinforcement Learning from Human Feedback (RLHF) aims to align language models (LMs) with human values by training reward models (RMs) on binary preferences and using these RMs to fine-tune the base LMs. Despite its importance, the internal mechanis
Externí odkaz:
http://arxiv.org/abs/2408.10270
Autor:
Rowley, Christopher D., Nelson, Mark C., Campbell, Jennifer S. W., Leppert, Ilana R., Pike, G. Bruce, Tardif, Christine L.
Purpose: Magnetization transfer saturation (MTsat) mapping is commonly used to examine the macromolecular content of brain tissue. This study compared variable flip angle (VFA) T1 mapping against compressed sensing (cs)MP2RAGE T1 mapping for accelera
Externí odkaz:
http://arxiv.org/abs/2310.09102
Autor:
Perrine Janiaud, Chiara Zecca, Anke Salmen, Pascal Benkert, Sabine Schädelin, Annette Orleth, Lilian Demuth, Aleksandra Maleska Maceski, Cristina Granziera, Johanna Oechtering, David Leppert, Tobias Derfuss, Lutz Achtnichts, Oliver Findling, Patrick Roth, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Robert Hoepner, Giulio Disanto, Claudio Gobbi, Leila Rooshenas, Matthias Schwenkglenks, Mark J. Lambiris, Ludwig Kappos, Jens Kuhle, Özgür Yaldizli, Lars G. Hemkens
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Treatment decisions for persons with relapsing–remitting multiple sclerosis (RRMS) rely on clinical and radiological disease activity, the benefit-harm profile of drug therapy, and preferences of patients and physicians. However
Externí odkaz:
https://doaj.org/article/2dbdfb286bde4ad5a8fa355b8dcd0b9d
Autor:
Jobsis, Huygen J., Fykouras, Kostas, Reinders, Joost W. C., van Katwijk, Jacco, Dorresteijn, Joren M., Arens, Tjom, Vollmer, Ina, Muscarella, Loreta A., Leppert, Linn, Hutter, Eline M.
Halide double perovskite semiconductors such as Cs2AgBiBr6 are widely investigated as a more stable, less toxic alternative to lead-halide perovskites in light conversion applications including photovoltaics and photoredox catalysis. However, the rel
Externí odkaz:
http://arxiv.org/abs/2307.12747
Halide double perovskites are an emerging class of semiconductors with tremendous chemical and electronic diversity. While their bandstructure features can be understood from frontier-orbital models, chemical intuition for optical excitations remains
Externí odkaz:
http://arxiv.org/abs/2306.11352
Autor:
Biega, Raisa-Ioana, Bokdam, Menno, Herrmann, Kai, Mohanraj, John, Skyrbeck, Dominik, Thelakkat, Mukundan, Retsch, Markus, Leppert, Linn
Ruddlesden-Popper hybrid halide perovskite are quasi-two-dimensional materials with a layered structure and structural dynamics that are determined by the interplay between the organic and inorganic layers. While their optical properties are governed
Externí odkaz:
http://arxiv.org/abs/2303.05852
Autor:
Leppert, Ilana R, Bontempi, Pietro, Rowley, Christopher D, Campbell, Jennifer SW, Nelson, Mark C, Schiavi, Simona, Pike, G Bruce, Daducci, Alessandro, Tardif, Christine L
We present a novel dual-encoded magnetization transfer (MT) and diffusion-weighted sequence and demonstrate its potential to resolve distinct properties of white matter fiber tracts at the sub-voxel level. The sequence was designed and optimized for
Externí odkaz:
http://arxiv.org/abs/2303.03449
Autor:
Jinhui Li, Zhengyi Deng, Simon John Christoph Soerensen, Linda Kachuri, Andres Cardenas, Rebecca E. Graff, John T. Leppert, Marvin E. Langston, Benjamin I. Chung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Exposure to ambient air pollution has significant adverse health effects; however, whether air pollution is associated with urological cancer is largely unknown. We conduct a systematic review and meta-analysis with epidemiological studies,
Externí odkaz:
https://doaj.org/article/06724a96884240748181d3023816ee3d
Autor:
Alfie Wearn, Stéfanie A. Tremblay, Christine L. Tardif, Ilana R. Leppert, Claudine J. Gauthier, Giulia Baracchini, Colleen Hughes, Patrick Hewan, Jennifer Tremblay-Mercier, Pedro Rosa-Neto, Judes Poirier, Sylvia Villeneuve, Taylor W. Schmitz, Gary R. Turner, R. Nathan Spreng, PREVENT-AD Research Group
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract The neuromodulatory subcortical nuclei within the isodendritic core (IdC) are the earliest sites of tauopathy in Alzheimer’s disease (AD). They project broadly throughout the brain’s white matter. We investigated the relationship between
Externí odkaz:
https://doaj.org/article/d8062ce17ab54c72b84934986e6ff3ee
Autor:
Rowley, Christopher D., Campbell, Jennifer S. W., Leppert, Ilana R., Nelson, Mark C., Pike, G. Bruce, Tardif, Christine L.
Purpose: Imaging biomarkers with increased myelin specificity are needed to better understand the complex progression of neurological disorders. Inhomogeneous magnetization transfer (ihMT) imaging is an emergent technique that has a high degree of sp
Externí odkaz:
http://arxiv.org/abs/2302.07297