Monitoring of argatroban and lepirudin anticoagulation in critically ill patients by conventional laboratory parameters and rotational thromboelastometry – a prospectively controlled randomized double-blind clinical trial

Autor: Martin Beiderlinden, Patrick Werner, Astrid Bahlmann, Johann Kemper, Tobias Brezina, Maximilian Schäfer, Klaus Görlinger, Holger Seidel, Peter Kienbaum, Tanja A. Treschan

Publikováno v: BMC Anesthesiology, Vol 18, Iss 1, Pp 1-15 (2018)

Abstract Background Argatroban or lepirudin anticoagulation therapy in patients with heparin induced thrombocytopenia (HIT) or HIT suspect is typically monitored using the activated partial thromboplastin time (aPTT). Although aPTT correlates well wi

Externí odkaz: https://doaj.org/article/4c7108324b734ddf8f4c726045ecb477

Superior outcomes with Argatroban for heparin-induced thrombocytopenia: a Bayesian network meta-analysis

Autor: Markus Tingart, Heike Schnöring, Giorgia Colarossi, Filippo Migliorini, Nima Hatam, Andromahi Trivellas, Nicola Maffulli

Publikováno v: International journal of clinical pharmacy : IJCP 43(4), 825-838 (2021). doi:10.1007/s11096-021-01260-z
International Journal of Clinical Pharmacy

International journal of clinical pharmacy : IJCP 43(4), 825-838 (2021). doi:10.1007/s11096-021-01260-z
Published by Springer, Dordrecht [u.a.]

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::068c18229a925f7c9136c3b6891413f6
https://doi.org/10.1007/s11096-021-01260-z

Ecarin based coagulation testing

Autor: Robert C. Gosselin, Jonathan Douxfils

Publikováno v: Gosselin, R C & Douxfils, J 2020, ' Ecarin based coagulation testing ', European Medical Journal Hematology, vol. 95, no. 7, pp. 863-869 . https://doi.org/10.1002/ajh.25852

Ecarin is derived from venom of Echis carinatus, and will activate prothrombin into meizothrombin which will then cleave fibrinogen to result in clot formation. Ecarin based testing has been described for decades, but these assays were typically rest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7d2032217e468b1a4de005404cb9600
https://doi.org/10.1002/ajh.25852

New Trends, Advantages and Disadvantages in Anticoagulation and Coating Methods Used in Extracorporeal Life Support Devices

Autor: Helena Pels, Tilman M. Hackeng, Justyna Swol, Silvia Mariani, Jutta Arens, Roberto Lorusso, Anne Willers, Jos G. Maessen

Publikováno v: Membranes, 11(8):617. Molecular Diversity Preservation International
Membranes
Membranes, Vol 11, Iss 617, p 617 (2021)

The use of extracorporeal life support (ECLS) devices has significantly increased in the last decades. Despite medical and technological advancements, a main challenge in the ECLS field remains the complex interaction between the human body, blood, a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26eb5029b73e9b5a2cae4de5f0a1bc97
https://research.utwente.nl/en/publications/77215f24-ede7-4841-b39c-7a5eec923efe

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