Prefrontal cortex astroglia modulate anhedonia-like behavior.

Autor: Codeluppi SA; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada., Xu M; Department of Psychiatry, Yale University, New Haven, CT, USA., Bansal Y; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada., Lepack AE; Department of Psychiatry, Yale University, New Haven, CT, USA., Duric V; Department of Psychiatry, Yale University, New Haven, CT, USA.; Department of Physiology and Pharmacology, Des Moines University, West Des Moines, IA, USA., Chow M; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada., Muir J; Integrated Program in Neuroscience, McGill University, Montréal, QC, Canada., Bagot RC; Department of Psychology, McGill University, Montreal, QC, Canada.; Ludmer Centre for Neuroinformatics and Mental Health, Montreal, QC, Canada., Licznerski P; Department of Psychiatry, Yale University, New Haven, CT, USA.; Department of Internal Medicine, Section of Endocrinology, Yale University, New Haven, CT, USA., Wilber SL; Department of Psychiatry, Yale University, New Haven, CT, USA., Sanacora G; Department of Psychiatry, Yale University, New Haven, CT, USA., Sibille E; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Duman RS; Department of Psychiatry, Yale University, New Haven, CT, USA., Pittenger C; Department of Psychiatry, Yale University, New Haven, CT, USA., Banasr M; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada. mounira.banasr@camh.ca.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada. mounira.banasr@camh.ca.; Department of Psychiatry, Yale University, New Haven, CT, USA. mounira.banasr@camh.ca.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. mounira.banasr@camh.ca.

Publikováno v: Molecular psychiatry [Mol Psychiatry] 2023 Nov; Vol. 28 (11), pp. 4632-4641. Date of Electronic Publication: 2023 Sep 11.

Prefrontal Cortex Astroglia Modulate Anhedonia-like Behavior.

Autor: Codeluppi SA; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada., Xu M; Department of Psychiatry, Yale University, New Haven, USA., Bansal Y; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada., Lepack AE; Department of Psychiatry, Yale University, New Haven, USA., Duric V; Department of Psychiatry, Yale University, New Haven, USA.; Department of Physiology and Pharmacology, Des Moines University, Iowa, USA., Chow M; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada., Muir J; Integrated Program in Neuroscience, McGill University, Montréal, Canada., Bagot RC; Department of Psychology, McGill University, Montreal, Canada.; Ludmer Centre for Neuroinformatics and Mental Health, Montreal, QC, Canada., Licznerski P; Department of Psychiatry, Yale University, New Haven, USA.; Department of Internal Medicine, Section of Endocrinology, Yale University, New Haven, USA., Wilber SL; Department of Psychiatry, Yale University, New Haven, USA., Sanacora G; Department of Psychiatry, Yale University, New Haven, USA., Sibille E; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada.; Department of Psychiatry, University of Toronto, Toronto, Canada., Duman RS; Department of Psychiatry, Yale University, New Haven, USA., Pittenger C; Department of Psychiatry, Yale University, New Haven, USA., Banasr M; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, Canada.; Department of Psychiatry, Yale University, New Haven, USA.; Department of Psychiatry, University of Toronto, Toronto, Canada.

Publikováno v: Research square [Res Sq] 2023 Jun 30. Date of Electronic Publication: 2023 Jun 30.

ZBTB7A regulates MDD-specific chromatin signatures and astrocyte-mediated stress vulnerability in orbitofrontal cortex.

Autor: Fulton SL; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bendl J; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York City, New York, USA., Gameiro-Ros I; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Fullard JF; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York City, New York, USA., Al-Kachak A; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lepack AE; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Stewart AF; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Singh S; Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; The Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA., Poller WC; Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; The Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA., Bastle RM; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Hauberg ME; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, New York, USA., Fakira AK; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Chen M; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cuttoli RD; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Cathomas F; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ramakrishnan A; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Gleason K; Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA., Shen L; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tamminga CA; Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX, USA., Milosevic A; Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, New York, USA., Russo SJ; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Swirski F; Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Diagnostic, Molecular and Interventional Radiology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; The Cardiovascular Research Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA., Blitzer RD; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, USA., Slesinger PA; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Roussos P; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Center for Dementia Research, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York, USA.; Mental Illness Research Education and Clinical Center (MIRECC), James J. Peters VA Medical Center, Bronx, New York, USA., Maze I; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York City, New York, USA.; Howard Hughes Medical Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 May 04. Date of Electronic Publication: 2023 May 04.

Histone H3 dopaminylation in ventral tegmental area underlies heroin-induced transcriptional and behavioral plasticity in male rats.

Autor: Fulton SL; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Mitra S; Department of Pharmacology and Toxicology, Program in Neuroscience, University at Buffalo, Buffalo, NY, 14214, USA., Lepack AE; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Martin JA; Department of Pharmacology and Toxicology, Program in Neuroscience, University at Buffalo, Buffalo, NY, 14214, USA., Stewart AF; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Converse J; Department of Pharmacology and Toxicology, Program in Neuroscience, University at Buffalo, Buffalo, NY, 14214, USA., Hochstetler M; Department of Pharmacology and Toxicology, Program in Neuroscience, University at Buffalo, Buffalo, NY, 14214, USA., Dietz DM; Department of Pharmacology and Toxicology, Program in Neuroscience, University at Buffalo, Buffalo, NY, 14214, USA. ddietz@buffalo.edu., Maze I; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ian.maze@mssm.edu.; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ian.maze@mssm.edu.; Howard Hughes Medical Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. ian.maze@mssm.edu.

Publikováno v: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2022 Sep; Vol. 47 (10), pp. 1776-1783. Date of Electronic Publication: 2022 Jan 29.

Ubiquitin-proteasomal regulation of chromatin remodeler INO80 in the nucleus accumbens mediates persistent cocaine craving.

Autor: Werner CT; Department of Pharmacology and Toxicology, Program in Neuroscience, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA., Mitra S; Department of Pharmacology and Toxicology, Program in Neuroscience, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA., Martin JA; Department of Pharmacology and Toxicology, Program in Neuroscience, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA., Stewart AF; Department of Pharmacology and Toxicology, Program in Neuroscience, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA., Lepack AE; Fishberg Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ramakrishnan A; Fishberg Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Gobira PH; Department of Pharmacology and Toxicology, Program in Neuroscience, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA.; Department of Physics and Chemistry, School of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo, Brazil., Wang ZJ; Department of Pharmacology and Toxicology, Program in Neuroscience, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA., Neve RL; Gene Delivery Technology Core, Massachusetts General Hospital, Cambridge, MA, USA., Gancarz AM; Department of Psychology, California State University, Bakersfield, Bakersfield, CA, USA., Shen L; Fishberg Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Maze I; Fishberg Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Dietz DM; Department of Pharmacology and Toxicology, Program in Neuroscience, Jacobs School of Medicine and Biomedical Sciences, The State University of New York at Buffalo, Buffalo, NY, USA.; Department of Psychology, The State University of New York at Buffalo, Buffalo, NY, USA.

Publikováno v: Science advances [Sci Adv] 2019 Oct 09; Vol. 5 (10), pp. eaay0351. Date of Electronic Publication: 2019 Oct 09 (Print Publication: 2019).