Zobrazeno 1 - 10
of 1 062
pro vyhledávání: '"Leost, M."'
Autor:
Abdel-Mohsen, Heba T.1 (AUTHOR) ht.abdel-mohsen@nrc.sci.eg
Publikováno v:
BMC Chemistry. 9/13/2024, Vol. 18 Issue 1, p1-19. 19p.
Autor:
Janeiro, Ana Margarida1 (AUTHOR) anamcjaneiro@gmail.com, Marques, Carolina S.2 (AUTHOR) carolsmarq@uevora.pt
Publikováno v:
Drugs & Drug Candidates. Sep2024, Vol. 3 Issue 3, p488-511. 24p.
Autor:
Zhao, Zheng1 (AUTHOR), Yuan, Ye2 (AUTHOR), Li, Shuang1 (AUTHOR), Wang, Xiaofeng1 (AUTHOR) 763812729@qq.com, Yang, Xue3 (AUTHOR) yangx@sj‐hospital.org
Publikováno v:
CNS Neuroscience & Therapeutics. Aug2024, Vol. 30 Issue 8, p1-21. 21p.
Indirubin, a bis-indole obtained from various natural sources, is responsible for the reported antileukemia activity of a Chinese Medicinal recipe, Danggui Longhui Wan. However, its molecular mechanism of action is still not well understood. In addit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::fd3b6335d8e3e5a39b2a3cae3b549dd3
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3091356
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3091356
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2004, 23, pp.8206-8215
Oncogene, 2004, 23, pp.8206-8215
Oncogene, Nature Publishing Group, 2004, 23, pp.8206-8215
Oncogene, 2004, 23, pp.8206-8215
Dysregulation of the centrosome duplication cycle has been implicated in tumorigenesis. Our previous work has shown that the human papillomavirus type 16 (HPV-16) E7 oncoprotein rapidly induces aberrant centrosome and centriole duplication in normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4e65410a409b83fd1e6458a66d1dc3b2
https://hal.archives-ouvertes.fr/hal-00018945
https://hal.archives-ouvertes.fr/hal-00018945
Publikováno v:
Trends in pharmacological sciences.
Trends in pharmacological sciences., 2004, 25, pp.471-480
Trends in pharmacological sciences., 2004, 25, pp.471-480
Three closely related forms of glycogen synthase kinase 3 (GSK-3alpha, GSK-3beta and GSK-3beta2) have a major role in Wnt and Hedgehog signaling pathways and regulate the cell-division cycle, stem-cell renewal and differentiation, apoptosis, circadia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0511ab0a67c2d13a8a26f5312484d1ac
https://hal.science/hal-00018947
https://hal.science/hal-00018947
Publikováno v:
Bioorganic and Medicinal Chemistry Letters
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2004, 11, pp.413-416
Bioorganic and Medicinal Chemistry Letters, 2004, 11, pp.413-416
Bioorganic and Medicinal Chemistry Letters, Elsevier, 2004, 11, pp.413-416
Bioorganic and Medicinal Chemistry Letters, 2004, 11, pp.413-416
Kenpaullone derivatives with a modified parent ring system were synthesized in order to develop kinase inhibitors with enhanced selectivity. Among the novel structures, 1-azakenpaullone was found to act as a selective GSK-3beta versus CDK1 inhibitor.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::884c3e2eff0f8de3485cc434e53cac27
https://hal.archives-ouvertes.fr/hal-00020128
https://hal.archives-ouvertes.fr/hal-00020128
Pharmacological inhibitors of glycogen synthase kinase-3 (GSK-3) and cyclin-dependent kinases have a promising potential for applications against several neurodegenerative diseases such as Alzheimer's disease. Indirubins, a family of bis-indoles isol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::5c9effa8752bb1c3ce50fbd3170027f5
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3022685
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3022685
Gastropod mollusks have been used for over 2500 years to produce the "Tyrian purple" dye made famous by the Phoenicians. This dye is constituted of mixed bromine-substituted indigo and indirubin isomers. Among these, the new natural product 6-bromoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::942ffd0460394940706c038337aadd2d
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3022841
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3022841