Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Leora Witkowski"'
Autor:
Leora Witkowski, Laura Palma, Evan Weber, Alexandre Rouette, Loubna Jouan, Andrea Liliam Gomez Corredor, Lara Reichman, Thai-Hoa Tran, Sonia Cellot, William Foulkes, Anne-Marie Laberge, Vincent-Philippe Lavallée, Catherine Goudie
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 100997- (2024)
Externí odkaz:
https://doaj.org/article/ebf1af968d5f4f378976fe7da83e82b5
Publikováno v:
Genetics in Medicine Open, Vol 1, Iss 1, Pp 100634- (2023)
Externí odkaz:
https://doaj.org/article/b2a41b6c5d6f4c1abea5bdaff2229ec9
Autor:
Mark Sorin, Sophie Camilleri-Broët, Emilie Pichette, Justin-Pierre Lorange, Nasim Haghandish, Laurie-Rose Dubé, André Lametti, Caroline Huynh, Leora Witkowski, George Zogopoulos, Yifan Wang, Hangjun Wang, Jonathan Spicer, Logan A. Walsh, Roni Rayes, Guy Rouleau, Alan Spatz, Andrea Liliam Gomez Corredor, Pierre Olivier Fiset
Publikováno v:
Cancer Treatment and Research Communications, Vol 35, Iss , Pp 100696- (2023)
Background: Lung cancer is the leading cause of cancer death in both men and women. Quebec has the highest lung cancer mortality out of all provinces in Canada, believed to be caused by higher smoking rates. Molecular testing for lung cancer is stand
Externí odkaz:
https://doaj.org/article/7240409f90f54785af03197a914fd316
Autor:
Yibo Xue, Jordan L. Morris, Kangning Yang, Zheng Fu, Xianbing Zhu, Fraser Johnson, Brian Meehan, Leora Witkowski, Amber Yasmeen, Tunde Golenar, Mackenzie Coatham, Geneviève Morin, Anie Monast, Virginie Pilon, Pierre Olivier Fiset, Sungmi Jung, Anne V. Gonzalez, Sophie Camilleri-Broet, Lili Fu, Lynne-Marie Postovit, Jonathan Spicer, Walter H. Gotlieb, Marie-Christine Guiot, Janusz Rak, Morag Park, William Lockwood, William D. Foulkes, Julien Prudent, Sidong Huang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
SMARCA4/2 loss in ovarian and lung cancers is associated with chemotherapy resistance. Here, the authors show that SMARCA4/2 deficiency in cancer cells reduces the expression of the ER-Ca2+ channel IP3R3 and subsequently calcium transfer to the mitoc
Externí odkaz:
https://doaj.org/article/bf575d4233b14e5f997658655553d914
Autor:
Yibo Xue, Jordan L. Morris, Kangning Yang, Zheng Fu, Xianbing Zhu, Fraser Johnson, Brian Meehan, Leora Witkowski, Amber Yasmeen, Tunde Golenar, Mackenzie Coatham, Geneviève Morin, Anie Monast, Virginie Pilon, Pierre Olivier Fiset, Sungmi Jung, Anne V. Gonzalez, Sophie Camilleri-Broet, Lili Fu, Lynne-Marie Postovit, Jonathan Spicer, Walter H. Gotlieb, Marie-Christine Guiot, Janusz Rak, Morag Park, William Lockwood, William D. Foulkes, Julien Prudent, Sidong Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/dd155e5301354bdea1495ad9acd130d1
Autor:
Yibo Xue, Brian Meehan, Elizabeth Macdonald, Sriram Venneti, Xue Qing D. Wang, Leora Witkowski, Petar Jelinic, Tim Kong, Daniel Martinez, Geneviève Morin, Michelle Firlit, Atefeh Abedini, Radia M. Johnson, Regina Cencic, Jay Patibandla, Hongbo Chen, Andreas I. Papadakis, Aurelie Auguste, Iris de Rink, Ron M. Kerkhoven, Nicholas Bertos, Walter H. Gotlieb, Blaise A. Clarke, Alexandra Leary, Michael Witcher, Marie-Christine Guiot, Jerry Pelletier, Josée Dostie, Morag Park, Alexander R. Judkins, Ralf Hass, Douglas A. Levine, Janusz Rak, Barbara Vanderhyden, William D. Foulkes, Sidong Huang
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is driven by SMARCA4 loss. Here the authors demonstrate that SCCOHT cells are highly sensitive to CDK4/6 inhibition and provide mechanistic insights, whereby this druggable vulnerability
Externí odkaz:
https://doaj.org/article/a9bfc57c02f44dfc91dacd68ff8a6a66
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 11 (2020)
Background Genetic testing in pediatric primary dilated cardiomyopathy (DCM) patients has identified numerous disease‐causing variants, but few studies have evaluated genetic testing outcomes in this population in the context of patient and familia
Externí odkaz:
https://doaj.org/article/3c734fa390d240348c8a19200a417285
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Background RASopathies are a group of disorders caused by disruptions to the RAS‒MAPK pathway. Despite being in the same pathway, Neurofibromatosis Type 1 (NF1) and Legius syndrome (LS) typically present with phenotypes distinct from Noona
Externí odkaz:
https://doaj.org/article/9fbe2bc5222e4e9e97bdc5d015997dd1
Autor:
Alex Rabinovich, Leora Witkowski, Ruthy Shaco-Levi, Mihai Meirovitz, Martin Hasselblatt, William D. Foulkes
Publikováno v:
Gynecologic Oncology Reports, Vol 12, Iss C, Pp 64-66 (2015)
Externí odkaz:
https://doaj.org/article/43972f7e44f54593993a5cfb2b5998ca
Publikováno v:
Gynecologic Oncology Reports, Vol 12, Iss C, Pp 20-22 (2015)
Externí odkaz:
https://doaj.org/article/2c8d470d1de24798ba31bf8ee7bbd039