Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Leora M Fox"'
Autor:
Joanna M Dragich, Takaaki Kuwajima, Megumi Hirose-Ikeda, Michael S Yoon, Evelien Eenjes, Joan R Bosco, Leora M Fox, Alf H Lystad, Tinmarla F Oo, Olga Yarygina, Tomohiro Mita, Satoshi Waguri, Yoshinobu Ichimura, Masaaki Komatsu, Anne Simonsen, Robert E Burke, Carol A Mason, Ai Yamamoto
Publikováno v:
eLife, Vol 5 (2016)
The regulation of protein degradation is essential for maintaining the appropriate environment to coordinate complex cell signaling events and to promote cellular remodeling. The Autophagy linked FYVE protein (Alfy), previously identified as a molecu
Externí odkaz:
https://doaj.org/article/bebc1d11f6ea4e1fa0d10407c60fe990
Autor:
Tara Leigh Spires-Jones, Leora M Fox, Anete eRozkalne, Rose ePitstick, George A Carlson, Aleksey G. Kazantsev
Publikováno v:
Frontiers in Pharmacology, Vol 3 (2012)
Tauopathies including tau-associated Frontotemporal dementia and Alzheimer’s disease are characterized pathologically by the formation of tau-containing neurofibrillary aggregates and neuronal loss, which contribute to cognitive decline. There are
Externí odkaz:
https://doaj.org/article/2e30408a73d141e98d63ef576c2e5813
Autor:
Kelly M. Andrew, Leora M. Fox
Publikováno v:
Journal of Huntington's Disease. 12:71-76
Recent years have been turbulent ones for the Huntington’s disease (HD) community. Three clinical trials for HD, including the first Phase 3 trial of a potentially disease modifying genetic therapy for HD, were all brought to a halt in March of 202
Autor:
Ai Yamamoto, Leora M. Fox
Publikováno v:
Autophagy
The role protein aggregates play in the pathogenesis of neurodegenerative diseases has been a question since their initial observation. In this autophagic punctum, we discuss our recent findings of how the selectivity scaffold/adaptor WDFY3/Alfy is r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eeef1cf6dc0505421049caef1930365b
https://europepmc.org/articles/PMC7144867/
https://europepmc.org/articles/PMC7144867/
Autor:
Christopher W. Johnson, Andrew S. Yoo, Joanna M. Dragich, Ioannis Dragatsis, Shawei Chen, Joan R Bosco, Leora M. Fox, Kiryung Kim, Katherine R. Croce, Ai Yamamoto, Evelien Eenjes, Lisa K. Randolph, Matheus B. Victor
Publikováno v:
Neuron
Despite being an autosomal dominant disorder caused by a known coding mutation in the gene HTT, Huntington's disease (HD) patients with similar trinucleotide repeat mutations can have an age of onset that varies by decades. One likely contributing fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fca822a79fe4ea3c463aa3db9a0c4e9e
https://europepmc.org/articles/PMC7060123/
https://europepmc.org/articles/PMC7060123/
Autor:
Takaaki Kuwajima, Evelien Eenjes, Megumi Hirose-Ikeda, Joan R Bosco, Satoshi Waguri, Ai Yamamoto, Masaaki Komatsu, Robert E. Burke, Michael S Yoon, Carol A. Mason, Yoshinobu Ichimura, Tinmarla F. Oo, Joanna M. Dragich, Leora M. Fox, Olga Yarygina, Alf Håkon Lystad, Tomohiro Mita, Anne Simonsen
Publikováno v:
eLife
eLife, Vol 5 (2016)
eLife, Vol 5 (2016)
The regulation of protein degradation is essential for maintaining the appropriate environment to coordinate complex cell signaling events and to promote cellular remodeling. The Autophagy linked FYVE protein (Alfy), previously identified as a molecu
Autor:
Robert E. Burke, Joanna M. Dragich, Joan R Bosco, Takaaki Kuwajima, Leora M. Fox, Yoshinobu Ichimura, Alf Håkon Lystad, Anne Simonsen, Evelien Eenjes, Megumi Hirose-Ikeda, Satoshi Waguri, Olga Yarygina, Masaaki Komatsu, Carol A. Mason, Tomohiro Mita, Michael S Yoon, Tinmarla F. Oo, Ai Yamamoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79de7bd7757d13cb72e9e4c25c7a0f52
https://doi.org/10.7554/elife.14810.026
https://doi.org/10.7554/elife.14810.026
Autor:
Marianne Berwick, Joanna Biazik, Angela Cadou, Zhi Chen, Swati Choksi, Zufeng Ding, Eeva-Liisa Eskelinen, Yong-Qi Fang, Leora M. Fox, Marc Francaux, Mitsunori Fukuda, Saeid Ghavami, Adrienne M. Gorman, Eric Hayat, Chien-An A. Hu, Mohammed-Ali Ishak, Koutaro Ishibashi, Richard Jäger, Cécile Jamart, Eija Jokitalo, Michael P. Lisanti, Shijie Liu, Zhenggang Liu, Zhihe Liu, Shin-ei Matsumoto, Hiroshi Matsuura, Andreas Mayer, Jawahar L. Mehta, Yubin Miao, Yumiko Motoi, Mariko Omatsu-Kanbe, Tassula Proikas-Cezanne, Ahmed F. Salem, Afshin Samali, Kohei Shimada, Laurel Sillerud, Larry Sklar, Federica Stogia, Zsuzsanna Takacs, Salina Torres, Helena Vihinen, Xianwei Wang, Kirsten White, Zhenglong Wu, Zhong-Feng Xue, Ai Yamamoto, Behzad Yeganeh, Lu Zhang, Yan Zhang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f05b930c11171f555237224ba549bf2e
https://doi.org/10.1016/b978-0-12-801043-3.00024-8
https://doi.org/10.1016/b978-0-12-801043-3.00024-8
Autor:
Leora M. Fox, Ai Yamamoto
A common feature of neurodegenerative disease is the accumulation of aggregated proteins. While the significance of these structures in pathogenesis is debated, the removal of aggregation-prone proteins may represent a means to counter neuronal dysfu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0426357563bec62032d991d7cd34b929
https://doi.org/10.1016/b978-0-12-801043-3.00007-8
https://doi.org/10.1016/b978-0-12-801043-3.00007-8
Publikováno v:
Journal of neurotrauma. 27(8)
Arginine vasopressin (AVP) has previously been shown to promote disruption of the blood-brain barrier, exacerbate edema, and augment the loss of neural tissue in various forms and models of brain injury. However, the mechanisms underlying these AVP a