Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Leor Zach"'
Autor:
Itzik Cooper, David Last, Orly Ravid, Daniel Rand, Erez Matsree, Liora Omesi, Chen Shemesh, Meir Liberman, Leor Zach, Orit Furman, Dianne Daniels, Sigal Liraz-Zaltsman, Yael Mardor, Shirley Sharabi
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-12 (2023)
Abstract Background Pharmacological treatment of CNS diseases is limited due to the presence of the blood-brain barrier (BBB). Recent years showed significant advancement in the field of CNS drug delivery enablers, with technologies such as MR-guided
Externí odkaz:
https://doaj.org/article/bb56778727ba447385070c29cbca3022
Autor:
Garima Chaturvedi, Avital Sarusi-Portuguez, Olga Loza, Ariel Shimoni-Sebag, Orly Yoron, Yaacov Richard Lawrence, Leor Zach, Ofir Hakim
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 970 (2024)
Radiation therapy is commonly used to treat glioblastoma multiforme (GBM) brain tumors. Ionizing radiation (IR) induces dose-specific variations in transcriptional programs, implicating that they are tightly regulated and critical components in the t
Externí odkaz:
https://doaj.org/article/0b136575a4bc4385927d1c8148333a2c
Neuro-ophthalmologic outcomes of standard versus hypo-fractionated stereotactic radiotherapy of AVPM
Autor:
Leor Zach, Amir Agami, Orit Furman, Moshe Attia, Zvi Cohen, Iris Ben-Bassat Mizrachi, Guy Tam, Zion Zibly, Ouzi Nissim, Roberto Spiegelmann, Ruth Huna-Baron
Publikováno v:
Radiation Oncology, Vol 16, Iss 1, Pp 1-10 (2021)
Abstract Background Most anterior visual pathway meningiomas (AVPM) are benign and slow-growing, but these tumors may affect visual functions, including visual acuity (VA) and visual field (VF). Due to location, most are treated non-surgically by fra
Externí odkaz:
https://doaj.org/article/469e9cfd5319478dbc85dd16064f4dbb
Autor:
Keren Porper, Leor Zach, Yael Shpatz, Bruria Ben-Zeev, Michal Tzadok, Elisheva Jan, Alisa Talianski, Colin E. Champ, Zvi Symon, Yair Anikster, Yaacov R. Lawrence
Publikováno v:
Nutrients, Vol 13, Iss 9, p 3093 (2021)
There is increasing interest in the use of a ketogenic diet for various adult disorders; however, the ability of adults to generate ketones is unknown. Our goal was to challenge the hypothesis that there would be no difference between adults and chil
Externí odkaz:
https://doaj.org/article/33297dd33b9f44c882e781006643c25a
Autor:
Leor Zach, David Guez, David Last, Dianne Daniels, Yuval Grober, Ouzi Nissim, Chen Hoffmann, Dvora Nass, Alisa Talianski, Roberto Spiegelmann, Zvi R Cohen, Yael Mardor
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52008 (2012)
The current standard of care for newly diagnosed glioblastoma multiforme (GBM) is resection followed by radiotherapy with concomitant and adjuvant temozolomide. Recent studies suggest that nearly half of the patients with early radiological deteriora
Externí odkaz:
https://doaj.org/article/494b22cef05649d6ade2b244c6c0f73c
Autor:
Zhichao Wu, Sharika Rajan, Hye-Jung Chung, Mark Raffeld, Pavalan Panneer Selvam, Leonille Schweizer, Arie Perry, David Samuel, Caterina Giannini, Aditya Ragunathan, Matthew P. Frosch, Michael S. Marshall, Daniel R. Boué, Kliment Donev, Stewart G. Neill, Igor Fernandes, Adam Resnick, Brian Rood, Thomas J. Cummings, Anne F. Buckley, Linda Szymanski, Osorio Lopes Abath Neto, Leor Zach, Howard Colman, Samuel Cheshier, Jennifer Ziskin, Manoj Tyagi, David Capper, Zied Abdullaev, Patrick J. Cimino, Martha Quezado, Drew Pratt, Kenneth Aldape
Publikováno v:
Acta Neuropathologica. 144:1175-1178
Autor:
Patrick J. Cimino, Courtney Ketchum, Rust Turakulov, Omkar Singh, Zied Abdullaev, Caterina Giannini, Peter Pytel, Giselle Yvette Lopez, Howard Colman, MacLean P. Nasrallah, Mariarita Santi, Igor Lima Fernandes, Jeff Nirschl, Sonika Dahiya, Stewart Neill, David Solomon, Eilis Perez, David Capper, Haresh Mani, Dario Caccamo, Matthew Ball, Michael Badruddoja, Rati Chkheidze, Sandra Camelo-Piragua, Joseph Fullmer, Sanda Alexandrescu, Gabrielle Yeaney, Charles Eberhart, Maria Martinez-Lage, Jie Chen, Leor Zach, B. K. Kleinschmidt-DeMasters, Marco Hefti, Maria-Beatriz Lopes, Nicholas Nuechterlein, Craig Horbinski, Fausto J. Rodriguez, Martha Quezado, Drew Pratt, Kenneth Aldape
Publikováno v:
Acta Neuropathol
High-grade astrocytoma with piloid features (HGAP) is a recently recognized glioma type whose classification is dependent on its global epigenetic signature. HGAP is characterized by alterations in the mitogen-activated protein kinase (MAPK) pathway,
Autor:
Keren Porper, Yael Mardor, Ariel Shimoni-Sebag, Zvi R. Cohen, Rina Hemi, Uri Amit, Hili Genssin, Yaacov Richard Lawrence, Leor Zach, Yael Shpatz, Hannah Kanety, Luba Plotkin, Orit Furman, Colin E. Champ, Elisheva Jan, Alisa Talianski, Ronit Goldman Pechthold, Zvi Symon, Yair Anikster
Publikováno v:
Journal of Neuro-Oncology. 153:487-496
Animal brain-tumor models have demonstrated a synergistic interaction between radiation therapy and a ketogenic diet (KD). Metformin has in-vitro anti-cancer activity, through AMPK activation and mTOR inhibition. We hypothesized that the metabolic st
Autor:
R. Spiegelman, Kevin Camphausen, Zvi R. Cohen, Zion Zibly, Leor Zach, Moshe Attia, Christian A. Graves, Uzi Nissim, A. Peled
Publikováno v:
J Clin Neurosci
Hemangioblastomas (HB) are benign low grade vascular tumors most frequently occurring in the cerebellum, brain stem, and spinal cord. Often associated with Von Hippel Lindau disease (VHL), the lesions are often multifocal requiring complex resection
Autor:
Jian Campian, Andrew Brenner, Patrick Y. Wen, Shifra Fain Shmueli, John de Groot, Tamar Rachmilewitz Minei, Laurence S. Freedman, Noa Lowenton-Spier, Leor Zach, Nicholas Butowski, Timothy F. Cloughesy, Benjamin M. Ellingson, Yael C Cohen
Publikováno v:
Neuro-Oncology. 22:705-717
BackgroundOfranergene obadenovec (VB-111) is an anticancer viral therapy that demonstrated in a phase II study a survival benefit for patients with recurrent glioblastoma (rGBM) who were primed with VB-111 monotherapy that was continued after progres