Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Leopoldo Paolo, Pucillo"'
Autor:
Vijay eBahadur, Daniela eMastronicola, Amit Kumar Singh, Hemandra Kumar Tiwari, Leopoldo Paolo Pucillo, Paolo eSarti, Brajendra Kumar Singh, Alessandro eGiuffre
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Giardiasis is a common diarrheal disease worldwide caused by the protozoan parasite Giardia (G.) intestinalis. It is urgent to develop novel drugs to treat giardiasis, due to increasing clinical resistance to the gold standard drug metronidazole (MTZ
Externí odkaz:
https://doaj.org/article/ca38fe203e9f4d8a8e4d389ab89fec7f
Autor:
Daniela Mastronicola, Micol Falabella, Fabrizio Testa, Leopoldo Paolo Pucillo, Miguel Teixeira, Paolo Sarti, Lígia M Saraiva, Alessandro Giuffrè
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 1, p e2631 (2014)
The microaerophilic protozoan parasite Giardia intestinalis, causative of one of the most common human intestinal diseases worldwide, infects the mucosa of the proximal small intestine, where it has to cope with O2 and nitric oxide (NO). Elucidating
Externí odkaz:
https://doaj.org/article/1e06c76655574262b473457aeb3e480a
Autor:
Fabrizio Poccia, Cristiana Gioia, Carla Montesano, Federico Martini, Douglas Horejsh, Concetta Castilletti, Leopoldo Paolo Pucillo, Maria Rosaria Capobianchi, Giuseppe Ippolito
Publikováno v:
Emerging Infectious Diseases, Vol 9, Iss 11, Pp 1468-1470 (2003)
Orthopoxvirus zoonosis or smallpox as result of bioterrorism or biological warfare represents a risk for epidemic spread. By monitoring T-cell responses by flow cytometry, we observed a recall response after recent vaccination against smallpox. When
Externí odkaz:
https://doaj.org/article/40051bca3a3d47ac9736bd4b8a3d2a7b
Autor:
Leopoldo Paolo Pucillo, Andrea Baiocchini, Carmine Mancone, Franca Del Nonno, Marco Tripodi, Vera van Noort, Tonino Alonzi, Claudia Montaldo, Nicolina Rotiroti, Giuseppe Ippolito, Laura Amicone, Alice Conigliaro, Angela Maria Cozzolino, Cecilia Battistelli, Simone Mattei
Publikováno v:
Proteomics
Proteomics, Wiley-VCH Verlag, 2014, 14 (9), pp.1107-15. ⟨10.1002/pmic.201300422⟩
Proteomics, Wiley-VCH Verlag, 2014, 14 (9), pp.1107-15. ⟨10.1002/pmic.201300422⟩
Hepatitis C virus (HCV)-induced iron overload has been shown to promote liver fibrosis, steatosis, and hepatocellular carcinoma. The zonal-restricted histological distribution of pathological iron deposits has hampered the attempt to perform large-sc
Autor:
Eleonora Cimini, Antonio D'Avolio, Massimo Tempestilli, Federica Elisei, Federico Martini, Leopoldo Paolo Pucillo, Tonino Alonzi, Pasquale Narciso, Emanuele Nicastri, Germana Grassi
Publikováno v:
Journal of Antimicrobial Chemotherapy. 69:1760-1766
Received 30 October 2013; returned 17 December 2013; revised 11 February 2014; accepted 17 February 2014Background: Antiretroviral therapy has considerably reduced HIVdisease progression, but complete eradicationofHIVcannotactuallybeachieved.Moreover
Autor:
Pasquale Narciso, Tecla Gasperi, Marzia Montalbano, Gianpiero D'Offizi, Paolo Ascenzi, Leopoldo Paolo Pucillo, Massimo Tempestilli, Antonio D'Avolio, Elisa Milano
Publikováno v:
IUBMB Life. 65:800-805
Telaprevir is a direct acting antiviral agent, used with pegylated interferon and ribavirin for the management of chronic hepatitis C virus (HCV) genotype 1 infection, in patients not responding to therapy with pegylated interferon and ribavirin only
Autor:
Enrico Brunetti, Stefania Pane, Antonino Di Caro, Elisa Busi-Rizzi, Vincenzo Schininà, Enrico Girardi, Linda Petrone, Claudio Angeletti, Leopoldo Paolo Pucillo, Lidia Colace, Giuseppe Maria Ettorre, Edoardo Pozio, Gilda Cuzzi, Antonella Teggi, E. Bordi, Angela Corpolongo, Delia Goletti
Publikováno v:
BioMed Research International
BioMed Research International, Vol 2013 (2013)
BioMed Research International, Vol 2013 (2013)
Background. Cystic echinococcosis (CE) is a chronic, clinically complex, and neglected disease. Its prevalence in Italy, a country of medium to high endemicity, remains poorly defined, as notification has long ceased to be mandatory.Methods. We set u
Autor:
Alessandro Giuffrè, Lígia M. Saraiva, E. Bordi, Leopoldo Paolo Pucillo, Miguel Teixeira, Fabrizio Testa, Daniela Mastronicola, Diane E. Cabelli, Paolo Sarti
Publikováno v:
Free Radical Biology and Medicine
Free Radical Biology and Medicine, Elsevier, 2011, 51 (8), pp.1567-74. ⟨10.1016/j.freeradbiomed.2011.07.017⟩
Free Radical Biology and Medicine, Elsevier, 2011, 51 (8), pp.1567-74. ⟨10.1016/j.freeradbiomed.2011.07.017⟩
Unlike superoxide dismutases (SODs), superoxide reductases (SORs) eliminate superoxide anion (O(2)(*-)) not through its dismutation, but via reduction to hydrogen peroxide (H(2)O(2)) in the presence of an electron donor. The microaerobic protist Giar
Autor:
Paolo Ascenzi, Rita Bellagamba, Stefania Notari, Massimo Tempestilli, Leopoldo Paolo Pucillo, Emanuele Nicastri, Pasquale Narciso, Chiara Tommasi
Publikováno v:
IUBMB Life. 61:470-475
Therapeutic drug monitoring is pivotal to improve the management of HIV infection. Here, a new HPLC–UV method to quantify simultaneously maraviroc and raltegravir levels in human plasma is reported. Remarkably, this is the first method for maraviro
Autor:
Jelena, Ivanovic, Ivanovic, Jelena, Emanuele, Nicastri, Nicastri, Emanuele, Paolo, Ascenzi, Ascenzi, Paolo, Rita, Bellagamba, Bellagamba, Rita, Elisabetta, De Marinis, De Marinis, Elisabetta, Stefania, Notari, Notari, Stefania, Leopoldo Paolo, Pucillo, Pucillo Leopoldo, Paolo, Valerio, Tozzi, Tozzi, Valerio, Giuseppe, Ippolito, Ippolito, Giuseppe, Pasquale, Narciso, Narciso, Pasquale
Publikováno v:
Current Medicinal Chemistry. 15:1925-1939
The rate of HIV-positive patients that fails to reach or to maintain a durable virological suppression under anti-retroviral (ARV) therapy might be as high as 50%, therefore new tools to improve ARV drug efficacy are urgently needed. Among others, th